Coupling of DNA binding and helicase activity is mediated by a conserved loop in the MCM protein.
about
Archaeal MCM Proteins as an Analog for the Eukaryotic Mcm2-7 Helicase to Reveal Essential Features of Structure and FunctionThe minichromosome maintenance replicative helicaseMCM ring hexamerization is a prerequisite for DNA-binding.Crystal structure of a near-full-length archaeal MCM: Functional insights for an AAA+ hexameric helicaseA conserved MCM single-stranded DNA binding element is essential for replication initiationInsights into the MCM functional mechanism: lessons learned from the archaeal MCM complex.Mutations in subdomain B of the minichromosome maintenance (MCM) helicase affect DNA binding and modulate conformational transitionsThe haloarchaeal MCM proteins: bioinformatic analysis and targeted mutagenesis of the β7-β8 and β9-β10 hairpin loops and conserved zinc binding domain cysteines.Eukaryotic Replicative Helicase Subunit Interaction with DNA and Its Role in DNA Replication.Different residues on the surface of the Methanothermobacter thermautotrophicus MCM helicase interact with single- and double-stranded DNA.Characterization of the MCM homohexamer from the thermoacidophilic euryarchaeon Picrophilus torridus.Steric exclusion and wrapping of the excluded DNA strand occurs along discrete external binding paths during MCM helicase unwinding.Analysis of the crystal structure of an active MCM hexamerThermococcus kodakarensis encodes three MCM homologs but only one is essential.Intersubunit allosteric communication mediated by a conserved loop in the MCM helicaseThe Mcm complex: unwinding the mechanism of a replicative helicase.Structural biology of MCM helicases.G364R mutation of MCM4 detected in human skin cancer cells affects DNA helicase activity of MCM4/6/7 complex.Mechanisms and regulation of DNA replication initiation in eukaryotes.Mutational analysis of conserved aspartic acid residues in the Methanothermobacter thermautotrophicus MCM helicase.Lamin B2 binding to minichromosome maintenance complex component 7 promotes non-small cell lung carcinogenesis.The solution structure of full-length dodecameric MCM by SANS and molecular modeling
P2860
Q26779724-97BC496D-FE9A-403C-B718-2A2FDEFC3327Q27002267-69B17EDB-91FE-473F-BFDB-BDE56FF4A6E2Q27324366-F7639A3E-7CD4-438B-9723-C79D62A61C48Q27653118-E7BDF64C-5A19-4F11-ABBE-63813EEB9F9BQ27682741-536DB201-D26A-481C-8908-58BCAC9A6C5DQ28281309-16DB9936-A259-44E0-9FCD-45F7F68C8F40Q28754382-47313D3A-E945-4573-9502-19740E6E8803Q30361283-22534033-0978-4E60-8641-51D9C78FF676Q33608503-3437A27D-C465-416E-BABF-49E3B0C93DB8Q34382444-4FA111ED-3F2B-4BFE-9204-CA93FF4697B1Q35169513-28D3A79E-994F-4361-A0FC-DAF910DDC487Q35174785-FEE7B109-C7EE-4A4A-AF67-B2B20F705F91Q35176524-CDD286BB-7977-4336-81BC-AA7234FE7455Q35617280-22600462-1EBC-44B2-9D54-877A5398A3C5Q37078991-4A2358AC-2E9D-4C8A-8A66-98CB5D966DC2Q37451513-8BEC59DB-73A3-431C-8502-DD8137E06080Q37603329-B89F41D8-F17D-4E91-91B4-23AB3D30C894Q38911821-D110ABDF-1E11-46D2-BB0C-A40D94771CC3Q39017132-8644E7F9-023B-4DE8-9282-DE2B3C0A6E43Q43030280-09A0993D-A35E-4BA8-9DA7-207A3D50C7EEQ47131489-29D5BC0F-D877-4F2E-B28F-77EB6021AE7CQ57755356-788A4D63-4626-4B51-B635-9A95C36FAB3D
P2860
Coupling of DNA binding and helicase activity is mediated by a conserved loop in the MCM protein.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Coupling of DNA binding and he ...... erved loop in the MCM protein.
@ast
Coupling of DNA binding and he ...... erved loop in the MCM protein.
@en
type
label
Coupling of DNA binding and he ...... erved loop in the MCM protein.
@ast
Coupling of DNA binding and he ...... erved loop in the MCM protein.
@en
prefLabel
Coupling of DNA binding and he ...... erved loop in the MCM protein.
@ast
Coupling of DNA binding and he ...... erved loop in the MCM protein.
@en
P2093
P2860
P356
P1476
Coupling of DNA binding and he ...... erved loop in the MCM protein.
@en
P2093
Eugene Melamud
Frederick P Schwarz
Nozomi Sakakibara
Rajesh Kasiviswanathan
Zvi Kelman
P2860
P304
P356
10.1093/NAR/GKM1160
P407
P577
2008-01-09T00:00:00Z