Etoposide and illegitimate DNA double-strand break repair in the generation of MLL translocations: new insights and new questions.
about
Revisiting the biology of infant t(4;11)/MLL-AF4+ B-cell acute lymphoblastic leukemiaBRG1 promotes the repair of DNA double-strand breaks by facilitating the replacement of RPA with RAD51.Replication-dependent and transcription-dependent mechanisms of DNA double-strand break induction by the topoisomerase 2-targeting drug etoposideUntangling the relationships between DNA repair pathways by silencing more than 20 DNA repair genes in human stable clones.Signatures of selection in fusion transcripts resulting from chromosomal translocations in human cancerGEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombinationEvidence for direct involvement of epirubicin in the formation of chromosomal translocations in t(15;17) therapy-related acute promyelocytic leukemiaATM modulates the loading of recombination proteins onto a chromosomal translocation breakpoint hotspot.Myeloperoxidase-dependent oxidation of etoposide in human myeloid progenitor CD34+ cellsDouble-strand break repair by interchromosomal recombination: an in vivo repair mechanism utilized by multiple somatic tissues in mammals.Molecular pathogenesis of secondary acute promyelocytic leukemiaFaithful after break-up: suppression of chromosomal translocations.DNA topoisomerase II, genotoxicity, and cancerEtoposide sensitivity does not predict MLL rearrangements or risk of therapy-related acute myeloid leukemia.Recognition of DNA double strand breaks by the BRCA1 tumor suppressor network.A role for epigenetics in the formation of chromosome translocations in acute leukemia.Etoposide-initiated MLL rearrangements detected at high frequency in human primitive hematopoietic stem cells with in vitro and in vivo long-term repopulating potential.Topoisomerase II and leukemia.Long-term effects of chromatin remodeling and DNA damage in stem cells induced by environmental and dietary agents.Deleterious effects of reactive metabolites.Dietary factors and the risk for acute infant leukemia: evaluating the effects of cocoa-derived flavanols on DNA topoisomerase activity.Prenatal exposure to flavonoids: implication for cancer risk.AML1/RUNX1 gene point mutations in childhood myeloid malignancies.Ovarian Aging in Women With BRCA Germline Mutations.
P2860
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P2860
Etoposide and illegitimate DNA double-strand break repair in the generation of MLL translocations: new insights and new questions.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Etoposide and illegitimate DNA ...... ew insights and new questions.
@ast
Etoposide and illegitimate DNA ...... ew insights and new questions.
@en
type
label
Etoposide and illegitimate DNA ...... ew insights and new questions.
@ast
Etoposide and illegitimate DNA ...... ew insights and new questions.
@en
prefLabel
Etoposide and illegitimate DNA ...... ew insights and new questions.
@ast
Etoposide and illegitimate DNA ...... ew insights and new questions.
@en
P2093
P1433
P1476
Etoposide and illegitimate DNA ...... ew insights and new questions.
@en
P2093
P304
P356
10.1016/J.DNAREP.2006.05.018
P577
2006-06-30T00:00:00Z