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Recent advances in isolation, synthesis, and evaluation of bioactivities of bispyrroloquinone alkaloids of marine originEwing's Sarcoma as a Second Malignancy in Long-Term Survivors of Childhood Hematologic MalignanciesCatalytic core of human topoisomerase IIα: insights into enzyme-DNA interactions and drug mechanismFlavonoid intake in European adults (18 to 64 years).Current knowledge and future research directions in treatment-related second primary malignancies.Oxidative Transformation of Demethoxy- and Bisdemethoxycurcumin: Products, Mechanism of Formation, and Poisoning of Human Topoisomerase IIαTackling the Cytotoxic Effect of a Marine Polycyclic Quinone-Type Metabolite: Halenaquinone Induces Molt 4 Cells Apoptosis via Oxidative Stress Combined with the Inhibition of HDAC and Topoisomerase Activities.Effects of Olive Metabolites on DNA Cleavage Mediated by Human Type II Topoisomerases.Ginkgo biloba leaf extract induces DNA damage by inhibiting topoisomerase II activity in human hepatic cellsInterlinked DNA nano-circles for measuring topoisomerase II activity at the level of single decatenation events.Mechanisms of Action and Reduced Cardiotoxicity of Pixantrone; a Topoisomerase II Targeting Agent with Cellular Selectivity for the Topoisomerase IIα Isoform.The ascidian natural product eusynstyelamide B is a novel topoisomerase II poison that induces DNA damage and growth arrest in prostate and breast cancer cellsA comprehensive survey of the mutagenic impact of common cancer cytotoxicsEffects of Secondary Metabolites from the Fungus Septofusidium berolinense on DNA Cleavage Mediated by Human Topoisomerase IIα.A "Double-Edged" Scaffold: Antitumor Power within the Antibacterial Quinolone.Antileukemic Scalarane Sesterterpenoids and Meroditerpenoid from Carteriospongia (Phyllospongia) sp., Induce Apoptosis via Dual Inhibitory Effects on Topoisomerase II and Hsp90.Low Grade Lymphoma Mimicking Metastatic Urothelial Carcinoma: When Do We Need Further Histologic Staging?Effects of mannose-binding lectin on pulmonary gene expression and innate immune inflammatory response to ozone.Chemical exposure and infant leukaemia: development of an adverse outcome pathway (AOP) for aetiology and risk assessment research.Genome-wide TOP2A DNA cleavage is biased toward translocated and highly transcribed loci.Trabectedin for sarcomas in daily clinical practice: analysis of 45 patients treated in a French institution.XPO1 Inhibition using Selinexor Synergizes with Chemotherapy in Acute Myeloid Leukemia by Targeting DNA Repair and Restoring Topoisomerase IIα to the Nucleus.Etoposide quinone is a covalent poison of human topoisomerase IIβ.Nitric oxide inhibits ATPase activity and induces resistance to topoisomerase II-poisons in human MCF-7 breast tumor cells.Role of Protein Linked DNA Breaks in Cancer.Investigation into experimental toxicological properties of plant protection products having a potential link to Parkinson's disease and childhood leukaemia†Novel xanthone-polyamine conjugates as catalytic inhibitors of human topoisomerase IIα.Novel trifluoromethylated 9-amino-3,4-dihydroacridin-1(2H)-ones act as covalent poisons of human topoisomerase IIα.Topoisomerases as anticancer targets.Coupling the core of the anticancer drug etoposide to an oligonucleotide induces topoisomerase II-mediated cleavage at specific DNA sequences.Alternative RNA Processing of Topoisomerase IIα in Etoposide-Resistant Human Leukemia K562 Cells: Intron Retention Results in a Novel C-Terminal Truncated 90-kDa Isoform.A flow cytometry-based method for a high-throughput analysis of drug-stabilized topoisomerase II cleavage complexes in human cells.Progression of chromosomal damage induced by etoposide in G2 phase in a DNA-PKcs-deficient context.Transmembrane TNF-alpha promotes chemoresistance in breast cancer cells.Endophytic Fungi-Alternative Sources of Cytotoxic Compounds: A Review.Polyamine-containing etoposide derivatives as poisons of human type II topoisomerases: Differential effects on topoisomerase IIα and IIβ
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P2860
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 03 February 2014
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Topoisomerase II and leukemia.
@en
Topoisomerase II and leukemia.
@nl
type
label
Topoisomerase II and leukemia.
@en
Topoisomerase II and leukemia.
@nl
prefLabel
Topoisomerase II and leukemia.
@en
Topoisomerase II and leukemia.
@nl
P2093
P2860
P356
P1476
Topoisomerase II and leukemia.
@en
P2093
Carolyn A Felix
David Grimwade
Maryjean Pendleton
Neil Osheroff
R Hunter Lindsey
P2860
P304
P356
10.1111/NYAS.12358
P407
P577
2014-02-03T00:00:00Z