Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.
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Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infectionRemodeling of the Host Cell Plasma Membrane by HIV-1 Nef and Vpu: A Strategy to Ensure Viral Fitness and PersistenceOropharyngeal Candidiasis in HIV Infection: Analysis of Impaired Mucosal Immune Response to Candida albicans in Mice Expressing the HIV-1 TransgeneSystems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivityOne protein to rule them all: modulation of cell surface receptors and molecules by HIV Nef.Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactionsHuman leukocyte antigens and HIV type 1 viral load in early and chronic infection: predominance of evolving relationshipsHIV-1 Nef inhibits Protease activity and its absence alters protein content of mature viral particlesReconstruction and Function of Ancestral Center-of-Tree Human Immunodeficiency Virus Type 1 ProteinsIn vivo analysis of highly conserved Nef activities in HIV-1 replication and pathogenesis.Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains.Tetherin Antagonism by HIV-1 Group M Nef Proteins.Efficient Vpu-Mediated Tetherin Antagonism by an HIV-1 Group O Strain.The transmembrane domain of HIV-1 Vpu is sufficient to confer anti-tetherin activity to SIVcpz and SIVgor Vpu proteins: cytoplasmic determinants of Vpu functionGuanidine alkaloid analogs as inhibitors of HIV-1 Nef interactions with p53, actin, and p56lck.A flow cytometry-based FRET assay to identify and analyse protein-protein interactions in living cells.Preserved MHC class II antigen processing in monocytes from HIV-infected individualsClass II transactivator (CIITA) enhances cytoplasmic processing of HIV-1 Pr55Gag.Human immunodeficiency virus type 1 inhibits DNA damage-triggered apoptosis by a Nef-independent mechanism.Human immunodeficiency virus-1 Nef expression induces intracellular accumulation of multivesicular bodies and major histocompatibility complex class II complexes: potential role of phosphatidylinositol 3-kinaseExogenous Nef is an inhibitor of Mycobacterium tuberculosis-induced tumor necrosis factor-alpha production and macrophage apoptosis.Nef induces multiple genes involved in cholesterol synthesis and uptake in human immunodeficiency virus type 1-infected T cells.Nef proteins from diverse groups of primate lentiviruses downmodulate CXCR4 to inhibit migration to the chemokine stromal derived factor 1.Primary sooty mangabey simian immunodeficiency virus and human immunodeficiency virus type 2 nef alleles modulate cell surface expression of various human receptors and enhance viral infectivity and replication.Human immunodeficiency virus Nef induces rapid internalization of the T-cell coreceptor CD8alphabetaCounteraction of HLA-C-mediated immune control of HIV-1 by Nef.Neuropathogenic SIVsmmFGb genetic diversity and selection-induced tissue-specific compartmentalization during chronic infection and temporal evolution of viral genes in lymphoid tissues and regions of the central nervous system.Characterization of the alpha interferon-induced postentry block to HIV-1 infection in primary human macrophages and T cells.Nef proteins from simian immunodeficiency virus-infected chimpanzees interact with p21-activated kinase 2 and modulate cell surface expression of various human receptorsThe presence of a vpu gene and the lack of Nef-mediated downmodulation of T cell receptor-CD3 are not always linked in primate lentivirusesHIV-1 pathogenicity and virion production are dependent on the metabolic phenotype of activated CD4+ T cellsA rare missense variant abrogates the signaling activity of tetherin/BST-2 without affecting its effect on virus releaseIntra- and intersubtype alternative Pak2-activating structural motifs of human immunodeficiency virus type 1 NefHIV-1 transcripts use IRES-initiation under conditions where Cap-dependent translation is restricted by poliovirus 2A proteaseMisdirection of membrane trafficking by HIV-1 Vpu and Nef: Keys to viral virulence and persistence.HLA-DR+ CD38+ CD4+ T lymphocytes have elevated CCR5 expression and produce the majority of R5-tropic HIV-1 RNA in vivo.Identification of potential HIV restriction factors by combining evolutionary genomic signatures with functional analysesIL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infectionA Genome-Wide Screen for Machinery Involved in Downregulation of MHC Class I by HIV-1 Nef.Efficient Nef-mediated downmodulation of TCR-CD3 and CD28 is associated with high CD4+ T cell counts in viremic HIV-2 infection
P2860
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P2860
Down-modulation of mature major histocompatibility complex class II and up-regulation of invariant chain cell surface expression are well-conserved functions of human and simian immunodeficiency virus nef alleles.
description
2003 nî lūn-bûn
@nan
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
2003年论文
@zh
2003年论文
@zh-cn
name
Down-modulation of mature majo ...... odeficiency virus nef alleles.
@ast
Down-modulation of mature majo ...... odeficiency virus nef alleles.
@en
type
label
Down-modulation of mature majo ...... odeficiency virus nef alleles.
@ast
Down-modulation of mature majo ...... odeficiency virus nef alleles.
@en
prefLabel
Down-modulation of mature majo ...... odeficiency virus nef alleles.
@ast
Down-modulation of mature majo ...... odeficiency virus nef alleles.
@en
P2093
P2860
P1433
P1476
Down-modulation of mature majo ...... nodeficiency virus nef alleles
@en
P2093
Matthias Brenner
Michael Schindler
Philippa Easterbrook
Rod Daniels
Stephanie Würfl
Thomas C Greenough
P2860
P304
10548-10556
P356
10.1128/JVI.77.19.10548-10556.2003
P407
P577
2003-10-01T00:00:00Z