A gradient of ATP affinities generates an asymmetric power stroke driving the chaperonin TRIC/CCT folding cycle.
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Contribution of the Type II Chaperonin, TRiC/CCT, to OncogenesisThe Crystal Structures of the Eukaryotic Chaperonin CCT Reveal Its Functional PartitioningDynamics, flexibility, and allostery in molecular chaperoninsThe structural basis of substrate recognition by the eukaryotic chaperonin TRiC/CCTxTract: software for characterizing conformational changes of protein complexes by quantitative cross-linking mass spectrometryReprogramming an ATP-driven protein machine into a light-gated nanocageAsymmetry in the function and dynamics of the cytosolic group II chaperonin CCT/TRiCSequential allosteric mechanism of ATP hydrolysis by the CCT/TRiC chaperone is revealed through Arrhenius analysisA direct regulatory interaction between chaperonin TRiC and stress-responsive transcription factor HSF1.Folding of large multidomain proteins by partial encapsulation in the chaperonin TRiC/CCT.Human CCT4 and CCT5 chaperonin subunits expressed in Escherichia coli form biologically active homo-oligomers.Chaperonin TRiC/CCT Recognizes Fusion Oncoprotein AML1-ETO through Subunit-Specific Interactions.The chaperonin CCT inhibits assembly of α-synuclein amyloid fibrils by a specific, conformation-dependent interaction.ATP-driven molecular chaperone machines.Internal (His)₆-tagging delivers a fully functional hetero-oligomeric class II chaperonin in high yield.The Mechanism and Function of Group II Chaperonins.Staggered ATP binding mechanism of eukaryotic chaperonin TRiC (CCT) revealed through high-resolution cryo-EM.Chaperone-client interactions: Non-specificity engenders multifunctionality.Regulation of GPCR expression through an interaction with CCT7, a subunit of the CCT/TRiC complex.The TCP1γ subunit of Leishmania donovani forms a biologically active homo-oligomeric complex.Chaperonin Containing TCP-1 Protein Level in Breast Cancer Cells Predicts Therapeutic Application of a Cytotoxic Peptide.Chaperonin containing TCP1 subunit 5 is a tumor associated antigen of non-small cell lung cancer.An information theoretic framework reveals a tunable allosteric network in group II chaperonins.Intraring allostery controls the function and assembly of a hetero-oligomeric class II chaperonin.Molecular determinants of the ATP hydrolysis asymmetry of the CCT chaperonin complexProtein folding in the cell, from atom to organism
P2860
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P2860
A gradient of ATP affinities generates an asymmetric power stroke driving the chaperonin TRIC/CCT folding cycle.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
A gradient of ATP affinities g ...... eronin TRIC/CCT folding cycle.
@ast
A gradient of ATP affinities g ...... eronin TRIC/CCT folding cycle.
@en
type
label
A gradient of ATP affinities g ...... eronin TRIC/CCT folding cycle.
@ast
A gradient of ATP affinities g ...... eronin TRIC/CCT folding cycle.
@en
prefLabel
A gradient of ATP affinities g ...... eronin TRIC/CCT folding cycle.
@ast
A gradient of ATP affinities g ...... eronin TRIC/CCT folding cycle.
@en
P2093
P2860
P1433
P1476
A gradient of ATP affinities g ...... eronin TRIC/CCT folding cycle.
@en
P2093
Anne S Meyer
Bryan Chen
Lukasz A Joachimiak
Stefanie Reissmann
P2860
P304
P356
10.1016/J.CELREP.2012.08.036
P577
2012-10-04T00:00:00Z