Multilayering and loss of apical polarity in MDCK cells transformed with viral K-ras.
about
Dysregulation of cell polarity proteins synergize with oncogenes or the microenvironment to induce invasive behavior in epithelial cellsErbB2, but not ErbB1, reinitiates proliferation and induces luminal repopulation in epithelial aciniCyr61 promotes epithelial-mesenchymal transition and tumor metastasis of osteosarcoma by Raf-1/MEK/ERK/Elk-1/TWIST-1 signaling pathway.Selective alterations in biosynthetic and endocytic protein traffic in Madin-Darby canine kidney epithelial cells expressing mutants of the small GTPase Rac1.Restoration of tight junction structure and barrier function by down-regulation of the mitogen-activated protein kinase pathway in ras-transformed Madin-Darby canine kidney cells.SOS1 and Ras regulate epithelial tight junction formation in the human airway through EMP1.Heterogeneity of the tumorigenic phenotype expressed by Madin-Darby canine kidney cellsRole of the microtubular system in morphological organization of normal and oncogene-transfected epithelial cells.Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human diseaseAn antiglycolipid antibody inhibits Madin-Darby canine kidney cell adhesion to laminin and interferes with basolateral polarization and tight junction formation.Polo-like kinase 1 induces epithelial-to-mesenchymal transition and promotes epithelial cell motility by activating CRAF/ERK signaling.Activation of both MAP kinase and phosphatidylinositide 3-kinase by Ras is required for hepatocyte growth factor/scatter factor-induced adherens junction disassembly.Polarity proteins regulate mammalian cell-cell junctions and cancer pathogenesisThyroid hormone regulates stromelysin expression, protease secretion and the morphogenetic potential of normal polarized mammary epithelial cellsClaudin family of proteins and cancer: an overview.Induced expression of Rnd3 is associated with transformation of polarized epithelial cells by the Raf-MEK-extracellular signal-regulated kinase pathway.NZO-3 expression causes global changes to actin cytoskeleton in Madin-Darby canine kidney cells: linking a tight junction protein to Rho GTPases.Ras mutation impairs epithelial barrier function to a wide range of nonelectrolytes.Par6-aPKC uncouples ErbB2 induced disruption of polarized epithelial organization from proliferation control.Spontaneously oscillating K+ channel activity in transformed Madin-Darby canine kidney cellsRaf induces TGFbeta production while blocking its apoptotic but not invasive responses: a mechanism leading to increased malignancy in epithelial cells.Rac1, but not RhoA, signaling protects epithelial adherens junction assembly during ATP depletion.Ras and TGF[beta] cooperatively regulate epithelial cell plasticity and metastasis: dissection of Ras signaling pathways.Oncogenic Raf-1 disrupts epithelial tight junctions via downregulation of occludin.Transforming growth factor-alpha abrogates glucocorticoid-stimulated tight junction formation and growth suppression in rat mammary epithelial tumor cells.Slow cellular dynamics in MDCK and R5 cells monitored by time-lapse atomic force microscopy.Nonpolarized surface distribution and delivery of human CD7 in polarized MDCK cells.Requirement for Ras and phosphatidylinositol 3-kinase signaling uncouples the glucocorticoid-induced junctional organization and transepithelial electrical resistance in mammary tumor cells.The establishment of polarity and enhanced transcytosis of transferrin receptors in enterocyte-like Caco-2 cells.Effects of mesenchyme on epithelial tissue architecture revealed by tissue recombination experiments between the submandibular gland and lung of embryonic mice.Cell polarity protein Par3 complexes with DNA-PK via Ku70 and regulates DNA double-strand break repair.
P2860
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P2860
Multilayering and loss of apical polarity in MDCK cells transformed with viral K-ras.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Multilayering and loss of apical polarity in MDCK cells transformed with viral K-ras.
@ast
Multilayering and loss of apical polarity in MDCK cells transformed with viral K-ras.
@en
type
label
Multilayering and loss of apical polarity in MDCK cells transformed with viral K-ras.
@ast
Multilayering and loss of apical polarity in MDCK cells transformed with viral K-ras.
@en
prefLabel
Multilayering and loss of apical polarity in MDCK cells transformed with viral K-ras.
@ast
Multilayering and loss of apical polarity in MDCK cells transformed with viral K-ras.
@en
P2093
P2860
P356
P1476
Multilayering and loss of apical polarity in MDCK cells transformed with viral K-ras.
@en
P2093
C A Schoenenberger
K S Matlin
P2860
P304
P356
10.1083/JCB.112.5.873
P407
P577
1991-03-01T00:00:00Z