Induced expression of Rnd3 is associated with transformation of polarized epithelial cells by the Raf-MEK-extracellular signal-regulated kinase pathway.
about
The hematopoiesis-specific GTP-binding protein RhoH is GTPase deficient and modulates activities of other Rho GTPases by an inhibitory functionSTAT1 is required for redifferentiation during Madin-Darby canine kidney tubulogenesisDirect interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cellsThe atypical Rho GTPase Wrch1 collaborates with the nonreceptor tyrosine kinases Pyk2 and Src in regulating cytoskeletal dynamicsPak1 and PIX regulate contact inhibition during epithelial wound healingSocius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers.RhoE binds to ROCK I and inhibits downstream signalingPak1 regulates the orientation of apical polarization and lumen formation by distinct pathwaysCrystal structure of Rnd3/RhoE: functional implicationsMechanism of multi-site phosphorylation from a ROCK-I:RhoE complex structureReciprocal inhibition between MyoD and STAT3 in the regulation of growth and differentiation of myoblastsB-RAF regulation of Rnd3 participates in actin cytoskeletal and focal adhesion organizationIntegrin-dependent actomyosin contraction regulates epithelial cell scattering.Rnd3 regulation of the actin cytoskeleton promotes melanoma migration and invasive outgrowth in three dimensionsRSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells.Inhibitors of Ras/Raf-1 interaction identified by two-hybrid screening revert Ras-dependent transformation phenotypes in human cancer cells.The RhoA GEF Syx is a target of Rnd3 and regulated via a Raf1-like ubiquitin-related domain.Beta1-integrin orients epithelial polarity via Rac1 and laminin.Cadherins and Pak1 control contact inhibition of proliferation by Pak1-betaPIX-GIT complex-dependent regulation of cell-matrix signaling.Regulation of Rnd3 localization and function by protein kinase C alpha-mediated phosphorylation.Induction of beta3-integrin gene expression by sustained activation of the Ras-regulated Raf-MEK-extracellular signal-regulated kinase signaling pathway.Direct interaction of Rnd1 with FRS2 beta regulates Rnd1-induced down-regulation of RhoA activity and is involved in fibroblast growth factor-induced neurite outgrowth in PC12 cells.ROCK1 is a potential combinatorial drug target for BRAF mutant melanomaFunction and regulation of Rnd proteins in cortical projection neuron migrationPKCα promotes the mesenchymal to amoeboid transition and increases cancer cell invasiveness.Analysis of transcriptional responses in the mouse dorsal striatum following acute 3,4-methylenedioxymethamphetamine (ecstasy): identification of extracellular signal-regulated kinase-controlled genes.The GTPase-deficient Rnd proteins are stabilized by their effectors.Interface between breast cancer cells and the tumor microenvironment using platelet-rich plasma to promote tumor angiogenesis - influence of platelets and fibrin bundles on the behavior of breast tumor cells.RhoE Is required for keratinocyte differentiation and stratification.An essential role for p120-catenin in Src- and Rac1-mediated anchorage-independent cell growth.Rho GTPases control specific cytoskeleton-dependent functions of hematopoietic stem cells.Modulation of RhoA-Rho kinase-mediated Ca2+ sensitization of rabbit myometrium during pregnancy - role of Rnd3.Rho GTPases, their post-translational modifications, disease-associated mutations and pharmacological inhibitors.Fractalkine-induced endothelial cell migration requires MAP kinase signaling.Simian virus 40 small tumor antigen induces deregulation of the actin cytoskeleton and tight junctions in kidney epithelial cells.RhoE inhibits cell cycle progression and Ras-induced transformation.RhoE controls myoblast alignment prior fusion through RhoA and ROCK.PDK1 regulates cancer cell motility by antagonising inhibition of ROCK1 by RhoE.Matrix metalloproteinase 13 (MMP13) and tissue inhibitor of matrix metalloproteinase 1 (TIMP1), regulated by the MAPK pathway, are both necessary for Madin-Darby canine kidney tubulogenesis.Intracellular signaling via ERK/MAPK completes the pathway for tubulogenic fibronectin in MDCK cells.
P2860
Q24292225-EE3CA430-0F1A-463A-90C9-2504697998D5Q24300702-E5C630FF-3B33-4254-8DFC-40181B457116Q24301058-634070BC-857E-4081-9E30-CA2B8698D484Q24304033-915D7134-330C-44CD-B887-A7AE652BFD47Q24314659-B70C1710-4F57-4375-8CE6-12637729869EQ24537280-8EDA47F4-256E-4917-84A7-5C6E74302223Q24675619-898F5B4E-6E52-4E5E-AC2D-2C6BB0554507Q27333195-9424BD43-EFF9-4971-8DD5-768E45E8055CQ27639465-23F5F4C7-1DC9-447F-97E4-6FF1924A5FC9Q27652622-64D97540-8867-4272-934C-FD765B164AB6Q28204258-A6B44884-E4D3-4D44-AF2E-680DC5B09486Q30443185-A92ED6D4-6B39-452E-B549-8A51CEF78CD2Q30443410-C75704A1-5E60-466F-95BC-CE1EBD06D5DFQ30486572-30D6283D-589F-488D-BEF8-858E844D460BQ30547051-4D09C4FA-0D81-4569-A527-7E9BC214EA7CQ31115129-FF3B42E5-D0FB-4474-A1F3-FE79BFD78933Q33682232-E583D73D-9659-4097-84A9-4933FB9D55A8Q33763545-AE9FEE2C-4F49-42BE-858F-33F3BEF7301AQ33769261-1B3B7D57-1403-4A7F-AFD6-748C11010D41Q33847070-AE7060C3-85F9-4C58-B13F-589F0EEF42D7Q33968056-5F254A64-DD85-4B1A-905C-6038691ED0DBQ34398837-2F2C8312-0576-4F5D-A3E2-8A695E7B317AQ34990555-67D92C95-F99E-4C8B-AAE2-843D8554E7DCQ35056615-0FE75431-C50E-4A3F-B62A-83CFB45EF278Q35618066-93D4B441-252A-408B-B6A9-9E1976BE8376Q36012516-A64F1689-B7BE-478B-B9CE-59D8A58FC3E9Q36234368-77523C1B-9B3A-4F0F-8DE7-F07D5A5DFD6DQ36277239-4F684B6E-DDE3-4714-837F-E64832CA48DEQ37035089-F74C4B5E-EE0A-47ED-9469-498253EC6616Q37106705-15B251E5-080F-4CA4-9B47-4134FE9B571BQ38151855-0FBB9726-99FC-4B90-B0CE-2A3D09DCE567Q38349188-84AC903E-3C3E-4C3E-84E2-5E230428E077Q38933808-F036AA91-2A7A-43FE-974E-26B5A7D51B4BQ39664954-76C158FA-A0B5-421A-B79F-7B38089C193EQ39733486-0B50E45D-9695-4D35-9620-EC78F7C0849AQ39961437-A104E98D-4A00-4034-9C67-D9FA6C3BE1FCQ39998131-827EAB16-D370-477B-8E68-7207E82F904AQ40023259-85C45960-CA34-4E61-8525-6A78BE68B37CQ40044475-A6295882-66FF-4C62-9052-0850400330A9Q40188747-D0881A78-E64A-4777-848E-DB195F85A77F
P2860
Induced expression of Rnd3 is associated with transformation of polarized epithelial cells by the Raf-MEK-extracellular signal-regulated kinase pathway.
description
2000 nî lūn-bûn
@nan
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
2000年论文
@zh
2000年论文
@zh-cn
name
Induced expression of Rnd3 is ...... gnal-regulated kinase pathway.
@en
Induced expression of Rnd3 is ...... gnal-regulated kinase pathway.
@nl
type
label
Induced expression of Rnd3 is ...... gnal-regulated kinase pathway.
@en
Induced expression of Rnd3 is ...... gnal-regulated kinase pathway.
@nl
prefLabel
Induced expression of Rnd3 is ...... gnal-regulated kinase pathway.
@en
Induced expression of Rnd3 is ...... gnal-regulated kinase pathway.
@nl
P2093
P2860
P1476
Induced expression of Rnd3 is ...... gnal-regulated kinase pathway.
@en
P2093
K E Mostov
P Rodriguez-Viciana
S H Hansen
P2860
P304
P356
10.1128/MCB.20.24.9364-9375.2000
P407
P577
2000-12-01T00:00:00Z