Defining principles of combination drug mechanisms of action
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Omega-3 Fatty Acids and Cancer Cell Cytotoxicity: Implications for Multi-Targeted Cancer TherapyStructure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewSystems biology approaches for advancing the discovery of effective drug combinationsIdentifying and quantifying heterogeneity in high content analysis: application of heterogeneity indices to drug discoveryDiscovery of Drug Synergies in Gastric Cancer Cells Predicted by Logical ModelingA model-guided analysis and perspective on the evolution and epidemiology of antibiotic resistance and its futureChemogenomics and orthology-based design of antibiotic combination therapiesSystematic Quality Control Analysis of LINCS DataUse of big data in drug development for precision medicine.Intratumor heterogeneity alters most effective drugs in designed combinations.Beyond the androgen receptor: new approaches to treating metastatic prostate cancer. Report of the 2013 Prouts Neck Prostate Cancer MeetingComputational analysis of image-based drug profiling predicts synergistic drug combinations: applications in triple-negative breast cancerDCDB 2.0: a major update of the drug combination database.Synergistic anticancer effect of cisplatin and Chal-24 combination through IAP and c-FLIPL degradation, Ripoptosome formation and autophagy-mediated apoptosis.A streamlined search technology for identification of synergistic drug combinations.A Pt(IV) Pro-drug Preferentially Targets Indoleamine-2,3-dioxygenase, Providing Enhanced Ovarian Cancer Immuno-ChemotherapyMechanistic Studies of the Anticancer Activity of An Octahedral Hexanuclear Pt(II) Cage.VEGF blockade enhances the antitumor effect of BRAFV600E inhibition.Addressing genetic tumor heterogeneity through computationally predictive combination therapy.Untargeted metabolomics analysis reveals key pathways responsible for the synergistic killing of colistin and doripenem combination against Acinetobacter baumannii.Cancer Systems Biology: a peek into the future of patient care?Approaches to in vitro tissue regeneration with application for human disease modeling and drug development.Counteracting antibiotic resistance: breaking barriers among antibacterial strategies.Clinical management of breast cancer heterogeneity.Network pharmacology applications to map the unexplored target space and therapeutic potential of natural products.Recent advances in siRNA delivery.A subset of platinum-containing chemotherapeutic agents kills cells by inducing ribosome biogenesis stress.Looking beyond the cancer cell for effective drug combinations.The Potent Inhibitory Effect of a Naproxen-Appended Cobalt(III)-Cyclam Complex on Cancer Stem Cells.Multi-scale Modeling in Clinical Oncology: Opportunities and Barriers to Success.Exploiting receptor tyrosine kinase co-activation for cancer therapy.Necroptosis-inducing rhenium(V) oxo complexes.A multichannel nanosensor for instantaneous readout of cancer drug mechanisms.Current Trends in Multidrug Optimization.Bidentate ligands on osmium(VI) nitrido complexes control intracellular targeting and cell death pathways.The breast cancer stem cell potency of copper(ii) complexes bearing nonsteroidal anti-inflammatory drugs and their encapsulation using polymeric nanoparticles.Intratumoral heterogeneity of the therapeutical response to gemcitabine and metformin.Drug-repurposing identified the combination of Trolox C and Cytisine for the treatment of type 2 diabetes.Using an RNAi Signature Assay To Guide the Design of Three-Drug-Conjugated Nanoparticles with Validated Mechanisms, In Vivo Efficacy, and Low ToxicityStructure-activity relationships and molecular docking studies of chromene and chromene based azo chromophores: A novel series of potent antimicrobial and anticancer agents.
P2860
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P2860
Defining principles of combination drug mechanisms of action
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Defining principles of combination drug mechanisms of action
@ast
Defining principles of combination drug mechanisms of action
@en
type
label
Defining principles of combination drug mechanisms of action
@ast
Defining principles of combination drug mechanisms of action
@en
prefLabel
Defining principles of combination drug mechanisms of action
@ast
Defining principles of combination drug mechanisms of action
@en
P2093
P2860
P356
P1476
Defining principles of combination drug mechanisms of action
@en
P2093
Justin R Pritchard
Kelsey L Capron
Luke A Gilbert
Michael T Hemann
Peter M Bruno
P2860
P304
P356
10.1073/PNAS.1210419110
P407
P577
2012-12-18T00:00:00Z