The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease - Wikidata - wikimedia - TriplyDB

The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease

The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease

http://www.wikidata.org/entity/Q36537921

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Neuroprotection and remyelination after autoimmune demyelination in mice that inducibly overexpress CXCL1 Th17 Cells Pathways in Multiple Sclerosis and Neuromyelitis Optica Spectrum Disorders: Pathophysiological and Therapeutic Implications Innate immunity in the central nervous system Chemokine receptor CXCR2: physiology regulator and neuroinflammation controller?Functional and pathogenic differences of Th1 and Th17 cells in experimental autoimmune encephalomyelitis The inflammasome pyrin contributes to pertussis toxin-induced IL-1β synthesis, neutrophil intravascular crawling and autoimmune encephalomyelitis Type 1 Diabetes Prone NOD Mice Have Diminished Cxcr1 mRNA Expression in Polymorphonuclear Neutrophils and CD4+ T Lymphocytes CXCR2-positive neutrophils are essential for cuprizone-induced demyelination: relevance to multiple sclerosis Myelin repair is accelerated by inactivating CXCR2 on nonhematopoietic cells.α(M)β(2)-integrin-intercellular adhesion molecule-1 interactions drive the flow-dependent trafficking of Guillain-Barré syndrome patient derived mononuclear leukocytes at the blood-nerve barrier in vitro.Myeloid cell transmigration across the CNS vasculature triggers IL-1β-driven neuroinflammation during autoimmune encephalomyelitis in mice.A protective role for ELR+ chemokines during acute viral encephalomyelitis.CXCR2 signaling protects oligodendrocytes and restricts demyelination in a mouse model of viral-induced demyelination.Interleukin 17A Promotes Lymphocytes Adhesion and Induces CCL2 and CXCL1 Release from Brain Endothelial Cells.ELR(+) chemokine signaling in host defense and disease in a viral model of central nervous system disease Antiviral immune responses: triggers of or triggered by autoimmunity?Trafficking of immune cells in the central nervous system GM-CSF-dependent, CD103+ dermal dendritic cells play a critical role in Th effector cell differentiation after subcutaneous immunization.Th17 cells in autoimmune demyelinating disease.Site-specific chemokine expression regulates central nervous system inflammation and determines clinical phenotype in autoimmune encephalomyelitis Neuronal I kappa B kinase beta protects mice from autoimmune encephalomyelitis by mediating neuroprotective and immunosuppressive effects in the central nervous system.Cytokine-regulated neutrophil recruitment is required for brain but not spinal cord inflammation during experimental autoimmune encephalomyelitis.The therapeutic effects of MSc1 nanocomplex, synthesized by nanochelating technology, on experimental autoimmune encephalomyelitic C57/BL6 mice EAE mediated by a non-IFN-γ/non-IL-17 pathway.Role of chemokines in CNS health and pathology: a focus on the CCL2/CCR2 and CXCL8/CXCR2 networks.Neutrophil contribution to spinal cord injury and repair.Potential immunological consequences of pharmacological suppression of gastric acid production in patients with multiple sclerosis.Neutralization of IL-9 ameliorates experimental autoimmune encephalomyelitis by decreasing the effector T cell population.Initiation and progression of axonopathy in experimental autoimmune encephalomyelitis.Deficiency of CXCR2, but not other chemokine receptors, attenuates autoantibody-mediated arthritis in a murine model Absence of IFN-γ increases brain pathology in experimental autoimmune encephalomyelitis-susceptible DRB1*0301.DQ8 HLA transgenic mice through secretion of proinflammatory cytokine IL-17 and induction of pathogenic monocytes/microglia into the centra RTL therapy for multiple sclerosis: a Phase I clinical study.CNS-targeted production of IL-17A induces glial activation, microvascular pathology and enhances the neuroinflammatory response to systemic endotoxemia.Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE.Central nervous system pathology progresses independently of KC and CXCR2 in globoid-cell leukodystrophy Neutrophil-related factors as biomarkers in EAE and MS.Interleukin-6, produced by resident cells of the central nervous system and infiltrating cells, contributes to the development of seizures following viral infection.CCR4 contributes to the pathogenesis of experimental autoimmune encephalomyelitis by regulating inflammatory macrophage function.Developmental endothelial locus-1 is a homeostatic factor in the central nervous system limiting neuroinflammation and demyelination.IL17 Mediates Pelvic Pain in Experimental Autoimmune Prostatitis (EAP)

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P2860

The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease

http://www.wikidata.org/entity/Q36537921

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2008 nî lūn-bûn

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name

The Th17-ELR+ CXC chemokine pa ...... vous system autoimmune disease

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The Th17-ELR+ CXC chemokine pa ...... vous system autoimmune disease

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type

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The Th17-ELR+ CXC chemokine pa ...... vous system autoimmune disease

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The Th17-ELR+ CXC chemokine pa ...... vous system autoimmune disease

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prefLabel

The Th17-ELR+ CXC chemokine pa ...... vous system autoimmune disease

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The Th17-ELR+ CXC chemokine pa ...... vous system autoimmune disease

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P1433

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P1433

Journal of Experimental Medicine

P1476

The Th17-ELR+ CXC chemokine pa ...... vous system autoimmune disease

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P2093

Mark Kroenke

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Praveen Rao

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Thaddeus Carlson

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Thomas E Lane

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P2860

Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog

Neutral proteases and disruption of the blood-brain barrier in rat

Interleukin-17 family members and inflammation

Absence of monocyte chemoattractant protein 1 in mice leads to decreased local macrophage recruitment and antigen-specific T helper cell type 1 immune response in experimental autoimmune encephalomyelitis

Relative expression software tool (REST©) for group-wise comparison and statistical analysis of relative expression results in real-time PCR

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

Neutrophils induce sequential focal changes in endothelial adherens junction components: role of elastase.

A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica.

P304

811-823

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scholarly article

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10.1084/JEM.20072404

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P433

4

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P478

205

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Benjamin M. Segal

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2008-03-17T00:00:00Z

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5505578

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18347102

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2292221

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