Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice. - Wikidata - wikimedia - TriplyDB

Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice.

Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice.

http://www.wikidata.org/entity/Q36537972

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Carbamylation-dependent activation of T cells: a novel mechanism in the pathogenesis of autoimmune arthritis Pathogenesis and prevention of rheumatic disease: focus on preclinical RA and SLE The effect of targeted rheumatoid arthritis therapies on anti-citrullinated protein autoantibody levels and B cell responses Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis Infections as a cause of autoimmune rheumatic diseases Loss of CD4 T-cell-dependent tolerance to proteins with modified amino acids Immune recognition of citrullinated epitopes.Preclinical rheumatoid arthritis: identification, evaluation, and future directions for investigation Antibodies to citrullinated protein antigens (ACPAs): clinical and pathophysiologic significance Secretome profiling with antibody microarrays.Peptidylarginine deiminase from Porphyromonas gingivalis citrullinates human fibrinogen and α-enolase: implications for autoimmunity in rheumatoid arthritis Periodontitis, Porphyromonas, and the pathogenesis of rheumatoid arthritis.ACPA-negative RA consists of two genetically distinct subsets based on RF positivity in Japanese N-α-benzoyl-N5-(2-chloro-1-iminoethyl)-L-ornithine amide, a protein arginine deiminase inhibitor, reduces the severity of murine collagen-induced arthritis.A single functional group substitution in c5a breaks B cell and T cell tolerance and protects against experimental arthritis.Epitope analysis of the collagen type V-specific T cell response in lung transplantation reveals an HLA-DRB1*15 bias in both recipient and donor.Bacterial superantigens promote acute nasopharyngeal infection by Streptococcus pyogenes in a human MHC Class II-dependent manner.Specificity and detection of insulin-reactive CD4+ T cells in type 1 diabetes in the nonobese diabetic (NOD) mouse.Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage.Infectomics and autoinfectomics: a tool to study infectious-induced autoimmunity.Prophylactic Injection of Recombinant Alpha-Enolase Reduces Arthritis Severity in the Collagen-Induced Arthritis Mice Model Cytokines pre-determined by genetic factors are involved in pathogenesis of Rheumatoid arthritis.Periodontal disease and rheumatoid arthritis: the evidence accumulates for complex pathobiologic interactions.Detection of autoantibodies to citrullinated BiP in rheumatoid arthritis patients and pro-inflammatory role of citrullinated BiP in collagen-induced arthritis.Quantitative and qualitative characterization of expanded CD4+ T cell clones in rheumatoid arthritis patients.Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies.Autoimmunity against fibrinogen mediates inflammatory arthritis in mice.Recognizing rheumatoid arthritis: oncoprotein survivin opens new possibilities: a population-based case-control study Do MHCII-presented neoantigens drive type 1 diabetes and other autoimmune diseases?T-cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles.Development of synthetic anti-cyclic citrullinated peptide antibody and its arthritogenic role.Citrullination only infrequently impacts peptide binding to HLA class II MHC Citrullinated calreticulin potentiates rheumatoid arthritis shared epitope signaling.Inhibition of peptidyl-arginine deiminases reverses protein-hypercitrullination and disease in mouse models of multiple sclerosis.Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition.Sialylation converts arthritogenic IgG into inhibitors of collagen-induced arthritis.Soluble alpha-enolase activates monocytes by CD14-dependent TLR4 signalling pathway and exhibits a dual function.Citrullination of fibronectin modulates synovial fibroblast behavior Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis

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Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice.

http://www.wikidata.org/entity/Q36537972

description

2008 nî lūn-bûn

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2008年の論文

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2008年論文

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2008年论文

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2008年论文

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name

Arthritis induced by posttrans ...... gen in DR4-IE transgenic mice.

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Arthritis induced by posttrans ...... gen in DR4-IE transgenic mice.

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type

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Arthritis induced by posttrans ...... gen in DR4-IE transgenic mice.

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Arthritis induced by posttrans ...... gen in DR4-IE transgenic mice.

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Arthritis induced by posttrans ...... gen in DR4-IE transgenic mice.

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Arthritis induced by posttrans ...... gen in DR4-IE transgenic mice.

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Arthritis induced by posttrans ...... gen in DR4-IE transgenic mice.

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P2093

Anthony M Jevnikar

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Bret Wehrli

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David A Bell

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David M Lee

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David Yue

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Ewa Cairns

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Jonathan A Hill

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William Brintnell

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William H Robinson

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Wolfgang Hueber

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P2860

Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin

Comparison of enzymatic properties between hPADI2 and hPADI4

Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies

Significance analysis of microarrays applied to the ionizing radiation response

Cluster analysis and display of genome-wide expression patterns

Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset

The relationship between predicted peptide-MHC class II affinity and T-cell activation in a HLA-DRbeta1*0401 transgenic mouse model

Insights into rheumatoid arthritis derived from the Sa immune system.

A combination of autoantibodies to cyclic citrullinated peptide (CCP) and HLA-DRB1 locus antigens is strongly associated with future onset of rheumatoid arthritis

Articular cartilage and changes in arthritis: noncollagenous proteins and proteoglycans in the extracellular matrix of cartilage

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967-979

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10.1084/JEM.20072051

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4

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205

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5461620

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18391064

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2292232

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