Antiviral therapy during primary simian immunodeficiency virus infection fails to prevent acute loss of CD4+ T cells in gut mucosa but enhances their rapid restoration through central memory T cells
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Targeted DNA mutagenesis for the cure of chronic viral infectionsTreatment with IL-7 prevents the decline of circulating CD4+ T cells during the acute phase of SIV infection in rhesus macaquesTherapeutic DNA vaccine induces broad T cell responses in the gut and sustained protection from viral rebound and AIDS in SIV-infected rhesus macaquesImpact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infectionAntiretroviral treatment start-time during primary SIV(mac) infection in macaques exerts a different impact on early viral replication and disseminationIn vivo CD8+ T-cell suppression of siv viremia is not mediated by CTL clearance of productively infected cells.Intestinal epithelial barrier disruption through altered mucosal microRNA expression in human immunodeficiency virus and simian immunodeficiency virus infectionsImmune dysregulation in human immunodeficiency virus infection: know it, fix it, prevent it?Heterogeneous memory T cells in antiviral immunity and immunopathologyEnhanced innate antiviral gene expression, IFN-α, and cytolytic responses are predictive of mucosal immune recovery during simian immunodeficiency virus infection.Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activationPartial efficacy of a VSV-SIV/MVA-SIV vaccine regimen against oral SIV challenge in infant macaquesDysregulation of anti-inflammatory annexin A1 expression in progressive Crohns DiseaseChronic binge alcohol consumption does not diminish effectiveness of continuous antiretroviral suppression of viral load in simian immunodeficiency virus-infected macaques.Early short-term antiretroviral therapy is associated with a reduced prevalence of CD8(+)FoxP3(+) T cells in simian immunodeficiency virus-infected controller rhesus macaques.The gut mucosal viral reservoir in HIV-infected patients is not the major source of rebound plasma viremia following interruption of highly active antiretroviral therapy.Disruption of intestinal CD4+ T cell homeostasis is a key marker of systemic CD4+ T cell activation in HIV-infected individuals.Selective HDAC inhibition for the disruption of latent HIV-1 infection.Cannabinoid neuroimmune modulation of SIV disease.Site-specific differences in T cell frequencies and phenotypes in the blood and gut of HIV-uninfected and ART-treated HIV+ adults.CD4 T cell depletion at the cervix during HIV infection is associated with accumulation of terminally differentiated T cells.Chronic HIV Infection Is Associated with Upregulation of Proinflammatory Cytokine and Chemokine and Alpha Defensin Gene Expression in Colorectal MucosaSIV-infection-driven changes of pattern recognition receptor expression in mesenteric lymph nodes and gut microbiota dysbiosis.Reduced inflammation and CD4 loss in acute SHIV infection during oral pre-exposure prophylaxisCharacterization of peripheral and mucosal immune responses in rhesus macaques on long-term tenofovir and emtricitabine combination antiretroviral therapy.Dynamics of memory B-cell populations in blood, lymph nodes, and bone marrow during antiretroviral therapy and envelope boosting in simian immunodeficiency virus SIVmac251-infected rhesus macaques.Chronic alcohol increases CD8+ T-cell immunosenescence in simian immunodeficiency virus-infected rhesus macaques.Selective targeting of the repressive transcription factors YY1 and cMyc to disrupt quiescent human immunodeficiency viruses.Microbial translocation in the pathogenesis of HIV infection and AIDS.Gut immune dysfunction through impaired innate pattern recognition receptor expression and gut microbiota dysbiosis in chronic SIV infectionAntiretroviral therapy prior to acute viral replication preserves CD4 T cells in the periphery but not in rectal mucosa during acute simian immunodeficiency virus infection.Heightened cytotoxic responses and impaired biogenesis contribute to early pathogenesis in the oral mucosa of simian immunodeficiency virus-infected rhesus macaques.Macrophages in vaginal but not intestinal mucosa are monocyte-like and permissive to human immunodeficiency virus type 1 infection.Divergent Annexin A1 expression in periphery and gut is associated with systemic immune activation and impaired gut immune response during SIV infection.Effect of combination antiretroviral therapy on Chinese rhesus macaques of simian immunodeficiency virus infectionHIV/AIDS vaccines: a need for new concepts?Alcohol's role in HIV transmission and disease progression.HIV persistence and the prospect of long-term drug-free remissions for HIV-infected individuals.Clinical management of acute HIV infection: best practice remains unknown.A simian immunodeficiency virus macaque model of highly active antiretroviral treatment: viral latency in the periphery and the central nervous system.
P2860
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P2860
Antiviral therapy during primary simian immunodeficiency virus infection fails to prevent acute loss of CD4+ T cells in gut mucosa but enhances their rapid restoration through central memory T cells
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
Antiviral therapy during prima ...... through central memory T cells
@ast
Antiviral therapy during prima ...... through central memory T cells
@en
type
label
Antiviral therapy during prima ...... through central memory T cells
@ast
Antiviral therapy during prima ...... through central memory T cells
@en
prefLabel
Antiviral therapy during prima ...... through central memory T cells
@ast
Antiviral therapy during prima ...... through central memory T cells
@en
P2093
P2860
P356
P1433
P1476
Antiviral therapy during prima ...... through central memory T cells
@en
P2093
Melanie Silvey
Satya Dandekar
Sumathi Sankaran
P2860
P304
P356
10.1128/JVI.02164-07
P407
P577
2008-02-13T00:00:00Z