The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress.
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Quantitative proteomics identifies the Myb-binding protein p160 as a novel target of the von Hippel-Lindau tumor suppressorProlyl 4-hydroxylaseThe structure and regulation of Cullin 2 based E3 ubiquitin ligases and their biological functionsPHD2: from hypoxia regulation to disease progressionThe putative RNA helicase HELZ promotes cell proliferation, translation initiation and ribosomal protein S6 phosphorylationIntermittent hypoxia regulates RNA polymerase II in hippocampus and prefrontal cortexiTRAQ proteomic identification of pVHL-dependent and -independent targets of Egln1 prolyl hydroxylase knockdown in renal carcinoma cells.Hypoxia inactivates the VHL tumor suppressor through PIASy-mediated SUMO modification.Prolyl hydroxylase 2: a novel regulator of β2 -adrenoceptor internalization.The function of hypoxia-inducible factor (HIF) is independent of the endoplasmic reticulum protein OS-9Involvement of net and Hif1alpha in distinct yet intricately linked hypoxia-induced signaling pathways.The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR.Ubiquitin/SUMO modification regulates VHL protein stability and nucleocytoplasmic localization.Proteomic dissection of the von Hippel-Lindau (VHL) interactome.VHL, the story of a tumour suppressor gene.Folliculin contributes to VHL tumor suppressing activity in renal cancer through regulation of autophagy.Complex cellular functions of the von Hippel-Lindau tumor suppressor gene: insights from model organisms.The Role of Elongin BC-Containing Ubiquitin Ligases.Hypoxia-inducible factor prolyl hydroxylase inhibition: robust new target or another big bust for stroke therapeutics?ERK5/BMK1 is a novel target of the tumor suppressor VHL: implication in clear cell renal carcinoma.Hypoxia-inducible factor prolyl hydroxylases as targets for neuroprotection by "antioxidant" metal chelators: From ferroptosis to stroke.Prolyl 4-hydroxylases, master regulators of the hypoxia response.Von hippel-lindau disease: a genetic and clinical review.Genetic modification of hypoxia signaling in animal models and its effect on cancer.Requirements for Skp1 processing by cytosolic prolyl 4(trans)-hydroxylase and α-N-acetylglucosaminyltransferase enzymes involved in O₂ signaling in dictyostelium.PHD1 regulates p53-mediated colorectal cancer chemoresistance.Hypoxic Adaptation in the Nervous System: Promise for Novel Therapeutics for Acute and Chronic Neurodegeneration.TRPM3 and miR-204 establish a regulatory circuit that controls oncogenic autophagy in clear cell renal cell carcinoma.Prolyl hydroxylase domain enzymes: important regulators of cancer metabolism.Ubiquitination and regulation of AURKA identifies a hypoxia-independent E3 ligase activity of VHL.In vivo HIF-mediated reductive carboxylation is regulated by citrate levels and sensitizes VHL-deficient cells to glutamine deprivation.In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation.The von Hippel-Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C.Prolyl hydroxylase EGLN3 regulates skeletal myoblast differentiation through an NF-kappaB-dependent pathway.von Hippel-Lindau-dependent patterns of RNA polymerase II hydroxylation in human renal clear cell carcinomasUtilization of an in vivo reporter for high throughput identification of branched small molecule regulators of hypoxic adaptation.Epigenome Aberrations: Emerging Driving Factors of the Clear Cell Renal Cell Carcinoma.Novel interactions of the von Hippel-Lindau (pVHL) tumor suppressor with the CDKN1 family of cell cycle inhibitors.The Roles of VHL-Dependent Ubiquitination in Signaling and Cancer.Inhibition of HIF-prolyl-4-hydroxylases prevents mitochondrial impairment and cell death in a model of neuronal oxytosis.
P2860
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P2860
The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
The von Hippel-Lindau tumor su ...... response to oxidative stress.
@ast
The von Hippel-Lindau tumor su ...... response to oxidative stress.
@en
type
label
The von Hippel-Lindau tumor su ...... response to oxidative stress.
@ast
The von Hippel-Lindau tumor su ...... response to oxidative stress.
@en
prefLabel
The von Hippel-Lindau tumor su ...... response to oxidative stress.
@ast
The von Hippel-Lindau tumor su ...... response to oxidative stress.
@en
P2093
P2860
P50
P356
P1476
The von Hippel-Lindau tumor su ...... response to oxidative stress.
@en
P2093
Katie Van Geyte
Maria F Czyzyk-Krzeska
Martin Schneider
Michael Wyder
Monica P Revelo
Monika L Ignacak
Olga Mikhaylova
Svetlana V Harbaugh
Teresa J Barankiewicz
P2860
P304
P356
10.1128/MCB.01231-07
P407
P577
2008-02-19T00:00:00Z