Targeting the Intracellular Environment in Cystic Fibrosis: Restoring Autophagy as a Novel Strategy to Circumvent the CFTR Defect.

Targeting the Intracellular Environment in Cystic Fibrosis: Restoring Autophagy as a Novel Strategy to Circumvent the CFTR Defect.

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http://www.wikidata.org/entity/Q36547077
Manipulating proteostasis to repair the F508del-CFTR defect in cystic fibrosisCFTR: a hub for kinases and crosstalk of cAMP and Ca2+Autophagy enhances bacterial clearance during P. aeruginosa lung infection.Restoration of CFTR function in patients with cystic fibrosis carrying the F508del-CFTR mutationNFκB is a central regulator of protein quality control in response to protein aggregation stresses via autophagy modulation.Reduced caveolin-1 promotes hyperinflammation due to abnormal heme oxygenase-1 localization in lipopolysaccharide-challenged macrophages with dysfunctional cystic fibrosis transmembrane conductance regulator.Autophagic clearance of bacterial pathogens: molecular recognition of intracellular microorganismsCysteamine re-establishes the clearance of Pseudomonas aeruginosa by macrophages bearing the cystic fibrosis-relevant F508del-CFTR mutation.Autophagy is deficient in nasal polyps: implications for the pathogenesis of the disease.Strategies for the etiological therapy of cystic fibrosis.Genetic deletion of keratin 8 corrects the altered bone formation and osteopenia in a mouse model of cystic fibrosis.Integration of botanicals in contemporary medicine: road blocks, checkpoints and go-ahead signals.Peripheral Protein Quality Control as a Novel Drug Target for CFTR Stabilizer
P2860

Targeting the Intracellular Environment in Cystic Fibrosis: Restoring Autophagy as a Novel Strategy to Circumvent the CFTR Defect.

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http://www.wikidata.org/entity/Q36547077
description
2013 nî lūn-bûn
@nan
2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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2013年论文
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2013年论文
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name
Targeting the Intracellular En ...... to Circumvent the CFTR Defect.
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Targeting the Intracellular En ...... to Circumvent the CFTR Defect.
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type
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Targeting the Intracellular En ...... to Circumvent the CFTR Defect.
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Targeting the Intracellular En ...... to Circumvent the CFTR Defect.
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Targeting the Intracellular En ...... to Circumvent the CFTR Defect.
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Targeting the Intracellular En ...... to Circumvent the CFTR Defect.
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Targeting the Intracellular En ...... to Circumvent the CFTR Defect.
@en
P2093
P2860
P304
P31
P356
P478
P50
P577
P5875
P698
P921
P932