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Core signaling pathways in human pancreatic cancers revealed by global genomic analysesReserve stem cells: Differentiated cells reprogram to fuel repair, metaplasia, and neoplasia in the adult gastrointestinal tractHeterogeneity and targeting of pancreatic cancer stem cellsAcute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the nestin cell lineageOncogenic Kras initiates leukemia in hematopoietic stem cellsAnalysis of mRNA profiles after MEK1/2 inhibition in human pancreatic cancer cell lines reveals pathways involved in drug sensitivity.Isoform-specific upregulation of palladin in human and murine pancreas tumors.Genome-scale analysis identifies GJB2 and ERO1LB as prognosis markers in patients with pancreatic cancer.Personalising pancreas cancer treatment: When tissue is the issue.Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras.The epidermal growth factor receptor inhibitor gefitinib prevents the progression of pancreatic lesions to carcinoma in a conditional LSL-KrasG12D/+ transgenic mouse model.p53 mutations change phosphatidylinositol acyl chain compositionInactivation of Brca2 cooperates with Trp53(R172H) to induce invasive pancreatic ductal adenocarcinomas in mice: a mouse model of familial pancreatic cancerActivation of the PIK3CA/AKT pathway suppresses senescence induced by an activated RAS oncogene to promote tumorigenesis.A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesisInactivation of Ink4a/Arf leads to deregulated expression of miRNAs in K-Ras transgenic mouse model of pancreatic cancer.Novel AKT1-GLI3-VMP1 pathway mediates KRAS oncogene-induced autophagy in cancer cells.Cyclin-dependent kinase 5 is amplified and overexpressed in pancreatic cancer and activated by mutant K-RasExomic sequencing of medullary thyroid cancer reveals dominant and mutually exclusive oncogenic mutations in RET and RAS.Histological complexities of pancreatic lesions from transgenic mouse models are consistent with biological and morphological heterogeneity of human pancreatic cancer.Stabilization of beta-catenin induces pancreas tumor formationGLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation.Genetic Diversity of Pancreatic Ductal Adenocarcinoma and Opportunities for Precision MedicineOverexpression of interleukin-1beta in the murine pancreas results in chronic pancreatitis.Regulation of pancreas plasticity and malignant transformation by Akt signaling.The sunset of somatic genetics and the dawn of epigenetics: a new frontier in pancreatic cancer researchChallenges and advances in mouse modeling for human pancreatic tumorigenesis and metastasisRole of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia.Far-Red and Near-Infrared Seminaphthofluorophores for Targeted Pancreatic Cancer Imaging.Dysregulation of Wnt/β-catenin signaling in gastrointestinal cancers.Role of epithelial-mesenchymal transition in pancreatic ductal adenocarcinoma: is tumor budding the missing link?Chromosome instability and carcinogenesis: insights from murine models of human pancreatic cancer associated with BRCA2 inactivationThe impact of hypoxia in pancreatic cancer invasion and metastasis.Pancreatic cancer cell lines as patient-derived avatars: genetic characterisation and functional utility.MicroRNA-206 functions as a pleiotropic modulator of cell proliferation, invasion and lymphangiogenesis in pancreatic adenocarcinoma by targeting ANXA2 and KRAS genes.Expression of E-cadherin repressors SNAIL, ZEB1 and ZEB2 by tumour and stromal cells influences tumour-budding phenotype and suggests heterogeneity of stromal cells in pancreatic cancerA novel experimental model for human mixed acinar-ductal pancreatic cancer.Overexpression of HER2 in the pancreas promotes development of intraductal papillary mucinous neoplasms in mice.
P2860
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P2860
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
2005年论文
@zh
2005年论文
@zh-cn
name
Ductal pancreatic cancer in humans and mice.
@ast
Ductal pancreatic cancer in humans and mice.
@en
type
label
Ductal pancreatic cancer in humans and mice.
@ast
Ductal pancreatic cancer in humans and mice.
@en
prefLabel
Ductal pancreatic cancer in humans and mice.
@ast
Ductal pancreatic cancer in humans and mice.
@en
P2860
P356
P1476
Ductal pancreatic cancer in humans and mice
@en
P2093
Tuveson DA
P2860
P356
10.1101/SQB.2005.70.040
P577
2005-01-01T00:00:00Z