Distinct functions of human RECQ helicases WRN and BLM in replication fork recovery and progression after hydroxyurea-induced stalling.
about
Werner syndrome: Clinical features, pathogenesis and potential therapeutic interventionsCharacterization of the Caenorhabditis elegans HIM-6/BLM helicase: unwinding recombination intermediatesInduction of homologous recombination following in utero exposure to DNA-damaging agents.The Drosophila Werner exonuclease participates in an exonuclease-independent response to replication stress.Nanobiomotors of archaeal DNA repair machineries: current research status and application potentialCellular deficiency of Werner syndrome protein or RECQ1 promotes genotoxic potential of hydroquinone and benzo[a]pyrene exposure.BLM SUMOylation regulates ssDNA accumulation at stalled replication forks."...Rewritten in the skin": clues to skin biology and aging from inherited disease.Human RecQ helicases in DNA repair, recombination, and replication.Nonenzymatic role for WRN in preserving nascent DNA strands after replication stress.Microwell arrays reveal cellular heterogeneity during the clonal expansion of transformed human cellsReplication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16DEssential role for Cdk2 inhibitory phosphorylation during replication stress revealed by a human Cdk2 knockin mutation.Homozygosity for the WRN Helicase-Inactivating Variant, R834C, does not confer a Werner syndrome clinical phenotype.Replication fork recovery and regulation of common fragile sites stability.Class I Histone Deacetylase HDAC1 and WRN RECQ Helicase Contribute Additively to Protect Replication Forks upon Hydroxyurea-induced Arrest.The WRN exonuclease domain protects nascent strands from pathological MRE11/EXO1-dependent degradation.Bloom's syndrome: Why not premature aging?: A comparison of the BLM and WRN helicases.Mitomycin C reduces abundance of replication forks but not rates of fork progression in primary and transformed human cells.Application of the microfluidic-assisted replication track analysis to measure DNA repair in human and mouse cellsCheckpoint-dependent and independent roles of the Werner syndrome protein in preserving genome integrity in response to mild replication stress.RecQ and Fe-S helicases have unique roles in DNA metabolism dictated by their unwinding directionality, substrate specificity, and protein interactions.PARI Regulates Stalled Replication Fork Processing To Maintain Genome Stability upon Replication Stress in Mice.
P2860
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P2860
Distinct functions of human RECQ helicases WRN and BLM in replication fork recovery and progression after hydroxyurea-induced stalling.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Distinct functions of human RE ...... hydroxyurea-induced stalling.
@ast
Distinct functions of human RE ...... hydroxyurea-induced stalling.
@en
type
label
Distinct functions of human RE ...... hydroxyurea-induced stalling.
@ast
Distinct functions of human RE ...... hydroxyurea-induced stalling.
@en
prefLabel
Distinct functions of human RE ...... hydroxyurea-induced stalling.
@ast
Distinct functions of human RE ...... hydroxyurea-induced stalling.
@en
P2860
P1433
P1476
Distinct functions of human RE ...... r hydroxyurea-induced stalling
@en
P2093
Frances Mao
Raymond Monnat
P2860
P304
P356
10.1016/J.DNAREP.2012.11.005
P577
2012-12-17T00:00:00Z