Werner syndrome protein interacts functionally with translesion DNA polymerases
about
Separate roles of structured and unstructured regions of Y-family DNA polymerasesHuman premature aging, DNA repair and RecQ helicasesGetting Ready for the Dance: FANCJ Irons Out DNA WrinklesThe Werner syndrome exonuclease facilitates DNA degradation and high fidelity DNA polymerization by human DNA polymerase δWerner syndrome: Clinical features, pathogenesis and potential therapeutic interventionsHuman exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repairBiochemical analysis of DNA polymerase η fidelity in the presence of replication protein ADNA structure and the Werner protein modulate human DNA polymerase delta-dependent replication dynamics within the common fragile site FRA16D.Mutation of the little finger domain in human DNA polymerase η alters fidelity when copying undamaged DNAWRN participates in translesion synthesis pathway through interaction with NBS1Involvement of Werner syndrome protein in MUTYH-mediated repair of oxidative DNA damage.Cellular deficiency of Werner syndrome protein or RECQ1 promotes genotoxic potential of hydroquinone and benzo[a]pyrene exposure.The Werner syndrome protein limits the error-prone 8-oxo-dG lesion bypass activity of human DNA polymerase kappa.Roles of the Werner syndrome RecQ helicase in DNA replication.Escherichia coli Rep DNA helicase and error-prone DNA polymerase IV interact physically and functionallyDNA helicases involved in DNA repair and their roles in cancerMutational heterogeneity in human cancers: origin and consequences.Proteome-wide identification of WRN-interacting proteins in untreated and nuclease-treated samples.Human RecQ helicases in DNA repair, recombination, and replication.Enhancement of human DNA polymerase η activity and fidelity is dependent upon a bipartite interaction with the Werner syndrome proteinMechanism of replicative DNA polymerase delta pausing and a potential role for DNA polymerase kappa in common fragile site replication.Distinct functions of human RECQ helicases WRN and BLM in replication fork recovery and progression after hydroxyurea-induced stalling.Clinical implications of the basic defects in Cockayne syndrome and xeroderma pigmentosum and the DNA lesions responsible for cancer, neurodegeneration and agingBiochemical analysis of active site mutations of human polymerase ηReplication stress and cancer: it takes two to tango.Rising from the RecQ-age: the role of human RecQ helicases in genome maintenanceTelomeres do the (un)twist: helicase actions at chromosome termini.Role of TLS DNA polymerases eta and kappa in processing naturally occurring structured DNA in human cellsTargeting an Achilles' heel of cancer with a WRN helicase inhibitorStrategic role of the ubiquitin-dependent segregase p97 (VCP or Cdc48) in DNA replication.Bloom's syndrome: Why not premature aging?: A comparison of the BLM and WRN helicases.The Werner's Syndrome protein collaborates with REV1 to promote replication fork progression on damaged DNA.The RecQ helicase WRN is required for normal replication fork progression after DNA damage or replication fork arrest.RecQ and Fe-S helicases have unique roles in DNA metabolism dictated by their unwinding directionality, substrate specificity, and protein interactions.
P2860
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P2860
Werner syndrome protein interacts functionally with translesion DNA polymerases
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Werner syndrome protein interacts functionally with translesion DNA polymerases
@ast
Werner syndrome protein interacts functionally with translesion DNA polymerases
@en
Werner syndrome protein interacts functionally with translesion DNA polymerases
@en-gb
Werner syndrome protein interacts functionally with translesion DNA polymerases
@nl
type
label
Werner syndrome protein interacts functionally with translesion DNA polymerases
@ast
Werner syndrome protein interacts functionally with translesion DNA polymerases
@en
Werner syndrome protein interacts functionally with translesion DNA polymerases
@en-gb
Werner syndrome protein interacts functionally with translesion DNA polymerases
@nl
prefLabel
Werner syndrome protein interacts functionally with translesion DNA polymerases
@ast
Werner syndrome protein interacts functionally with translesion DNA polymerases
@en
Werner syndrome protein interacts functionally with translesion DNA polymerases
@en-gb
Werner syndrome protein interacts functionally with translesion DNA polymerases
@nl
P2093
P2860
P921
P3181
P356
P1476
Werner syndrome protein interacts functionally with translesion DNA polymerases
@en
P2093
Akira Yasui
Ashwini S Kamath-Loeb
Lawrence A Loeb
Satoshi Nakajima
P2860
P304
P3181
P356
10.1073/PNAS.0702513104
P407
P577
2007-06-19T00:00:00Z