Palmitoylation of either Cys-3 or Cys-5 is required for the biological activity of the Lck tyrosine protein kinase
about
Binding of HIV-1 Nef to a novel thioesterase enzyme correlates with Nef-mediated CD4 down-regulationDeciphering the cross talk between hnRNP K and c-Src: the c-Src activation domain in hnRNP K is distinct from a second interaction siteThe activated form of the Lck tyrosine protein kinase in cells exposed to hydrogen peroxide is phosphorylated at both Tyr-394 and Tyr-505Localization of the adhesion receptor glycoprotein Ib-IX-V complex to lipid rafts is required for platelet adhesion and activationThe Lck SH3 domain negatively regulates localization to lipid rafts through an interaction with c-Cbl.The Lck binding domain of herpesvirus saimiri tip-484 constitutively activates Lck and STAT3 in T cells.Single-molecule microscopy reveals plasma membrane microdomains created by protein-protein networks that exclude or trap signaling molecules in T cells.Interaction between src family kinases and rho-kinase in agonist-induced Ca2+-sensitization of rat pulmonary artery.Dynamic palmitoylation and the role of DHHC proteins in T cell activation and anergy.S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes.G Protein-regulated inducer of neurite outgrowth (GRIN) modulates Sprouty protein repression of mitogen-activated protein kinase (MAPK) activation by growth factor stimulation.Vpu binds directly to tetherin and displaces it from nascent virions.Transmembrane adapters: attractants for cytoplasmic effectors.Systems Analysis of Protein Fatty Acylation in Herpes Simplex Virus-Infected Cells Using Chemical ProteomicsSubcellular distribution of Lck during CD4 T-cell maturation in the thymic medulla regulates the T-cell activation threshold.Rapid and transient palmitoylation of the tyrosine kinase Lck mediates Fas signalingMultiple features of the p59fyn src homology 4 domain define a motif for immune-receptor tyrosine-based activation motif (ITAM) binding and for plasma membrane localizationExclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains.Intrinsic signals in the unique domain target p56(lck) to the plasma membrane independently of CD4.c-Yes response to growth factor activation.Trafficking of an acylated cytosolic protein: newly synthesized p56(lck) travels to the plasma membrane via the exocytic pathway.CD44 engagement promotes matrix-derived survival through the CD44-SRC-integrin axis in lipid raftsProtein acylation and localization in T cell signaling (Review).The role of membrane rafts in Lck transport, regulation and signalling in T-cells.Hsp90 is essential for the synthesis and subsequent membrane association, but not the maintenance, of the Src-kinase p56(lck).Cleavage of Fyn and Lyn in their N-terminal unique regions during induction of apoptosis: a new mechanism for Src kinase regulation.Lipid-modified, cysteinyl-containing peptides of diverse structures are efficiently S-acylated at the plasma membrane of mammalian cells.Stimulation of phosphorylation of Tyr394 by hydrogen peroxide reactivates biologically inactive, non-membrane-bound forms of Lck.Ultraviolet light-induced stimulation of the JNK mitogen-activated protein kinase in the absence of src family tyrosine kinase activation.Lipid-dependent recruitment of neuronal Src to lipid rafts in the brain.Akr1p-dependent palmitoylation of Yck2p yeast casein kinase 1 is necessary and sufficient for plasma membrane targeting.Posttranslational modification of voltage-dependent potassium channel Kv1.5: COOH-terminal palmitoylation modulates its biological properties.Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies.Targeting palmitoyl acyltransferase ZDHHC21 improves gut epithelial barrier dysfunction resulting from burn-induced systemic inflammation.Lack of Palmitoylation Redirects p59Hckfrom the Plasma Membrane to p61Hck-positive Lysosomes
P2860
Q24321956-AE4D8912-05FB-4D51-9C7C-DFA12124D259Q24337409-1F99BEB7-4989-440A-85ED-F59B79E92938Q28570842-53883777-9107-434C-8DA8-CFD0B539BE11Q28629042-B0CE469F-B5F7-480C-BADA-874677D0B77CQ30167736-1E9EB6E4-D6B8-4316-AA48-44B17D26571EQ30175910-8E5938DF-FE1C-414F-BE4B-E86A5C61BE28Q30493983-5B197FBD-9560-4532-9DD9-2F9585F53DABQ33703906-87F6462E-2D6F-42CA-99AA-AEF632ECD43CQ33779818-096AF90F-5230-4820-A5C2-C155D92BCF22Q33887288-E3B6EA99-1F81-4D35-9948-5BBB753B750EQ34181221-CA198ECA-F521-4252-A938-5C716C553CD9Q34697856-0DC72858-AAF8-4D54-9F55-F68A102E1B2FQ35076700-E4C3411B-F694-4FE9-AA0D-103667C8946FQ35976068-F40A7D79-C4B1-4624-965A-402227E2CC1CQ35982959-851756B8-F77E-44EC-A328-89B1B2013B48Q36103040-DD72286B-F71E-4C9B-9E41-D3FCF6FADF99Q36236925-A6D4BFD3-A4FF-4940-BE2B-ED21694DD7A8Q36257685-9C8C4456-1B5D-4E02-91E1-08E8DF37C292Q36262070-01F22357-C0D7-4CC9-872E-5FB34002A0CCQ36336583-0E63D2D6-C9E0-4338-AF1C-A0FFD54484CFQ36342168-2129F9C8-8E56-498C-806B-CFC6E21CC08AQ36898765-A801BD63-BB37-4B74-87A8-DB3C87AA257CQ37359997-020494B7-5690-4D8D-A1C8-5E3210E69519Q38127836-AFFEB7E4-5D59-4007-A944-FBA2FAD43D52Q38482173-175AEF6D-403C-47BA-9756-907C01019C8EQ40783235-41E10BDA-3622-42CE-8273-42F7CC601418Q41182094-1C4203DD-2D4B-408B-A157-A1A9DCD73640Q41197822-A2B5E148-04EE-4A25-9456-88B3F7EDB25CQ41734780-B3842E35-2244-4F03-B0C7-3C5966E66EC2Q44545603-F68C62DA-A17A-41B4-9C88-8568DC950D14Q44856926-4D14DF00-2E2E-4B27-B3DC-02DA46C882DAQ46698840-849D2FDB-1BDF-4CB9-B5E4-A468E5CF8266Q47239374-1B303CDF-4E76-489E-9300-81962EE7111AQ47909088-7E8CFF43-656C-4750-876F-C6428037222EQ57911562-6656AA1C-8077-4EAE-9161-1F66D1864626
P2860
Palmitoylation of either Cys-3 or Cys-5 is required for the biological activity of the Lck tyrosine protein kinase
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Palmitoylation of either Cys-3 ...... he Lck tyrosine protein kinase
@ast
Palmitoylation of either Cys-3 ...... he Lck tyrosine protein kinase
@en
type
label
Palmitoylation of either Cys-3 ...... he Lck tyrosine protein kinase
@ast
Palmitoylation of either Cys-3 ...... he Lck tyrosine protein kinase
@en
prefLabel
Palmitoylation of either Cys-3 ...... he Lck tyrosine protein kinase
@ast
Palmitoylation of either Cys-3 ...... he Lck tyrosine protein kinase
@en
P2860
P356
P1476
Palmitoylation of either Cys-3 ...... he Lck tyrosine protein kinase
@en
P2093
B M Sefton
L K Yurchak
P2860
P304
P356
10.1128/MCB.15.12.6914
P407
P577
1995-12-01T00:00:00Z