Interaction of the v-Rel oncoprotein with NF-kappaB and IkappaB proteins: heterodimers of a transformation-defective v-Rel mutant and NF-2 are functional in vitro and in vivo.
about
Mutational analysis of the v-Rel dimerization interface reveals a critical role for v-Rel homodimers in transformationMultiple mutations contribute to the oncogenicity of the retroviral oncoprotein v-Rel.Apoptosis promotes a caspase-induced amino-terminal truncation of IkappaBalpha that functions as a stable inhibitor of NF-kappaB.BMS-345541 targets inhibitor of kappaB kinase and induces apoptosis in melanoma: involvement of nuclear factor kappaB and mitochondria pathways.Malignant transformation of primary chicken spleen cells by human transcription factor c-Rel.Mutant envelope residues confer a transactivation function onto N-terminal sequences of the v-Rel oncoprotein.Deletion of either C-terminal transactivation subdomain enhances the in vitro transforming activity of human transcription factor REL in chicken spleen cells.
P2860
Q24537610-840E8C39-1F7A-47CC-9CAB-06928E7A5442Q33797168-97C0598A-BF7F-4E94-8B7E-5AA02E6D0CDFQ38322916-1A484752-7F16-48A3-92F8-A1D16C3CC821Q40318894-69429C94-B834-4FCF-8E8D-D92132EF3011Q40769231-1170E63F-FF46-4C4E-97D4-2E52B392CAE7Q40896731-6F2D2F7C-F227-479D-87E5-D4E1D395617BQ44611183-F641BE47-65F3-4DC8-8F1C-4330613E934C
P2860
Interaction of the v-Rel oncoprotein with NF-kappaB and IkappaB proteins: heterodimers of a transformation-defective v-Rel mutant and NF-2 are functional in vitro and in vivo.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Interaction of the v-Rel oncop ...... nctional in vitro and in vivo.
@ast
Interaction of the v-Rel oncop ...... nctional in vitro and in vivo.
@en
type
label
Interaction of the v-Rel oncop ...... nctional in vitro and in vivo.
@ast
Interaction of the v-Rel oncop ...... nctional in vitro and in vivo.
@en
prefLabel
Interaction of the v-Rel oncop ...... nctional in vitro and in vivo.
@ast
Interaction of the v-Rel oncop ...... nctional in vitro and in vivo.
@en
P2093
P2860
P356
P1476
Interaction of the v-Rel oncop ...... nctional in vitro and in vivo.
@en
P2093
P2860
P304
P356
10.1128/MCB.16.3.1169
P407
P577
1996-03-01T00:00:00Z