Chromatin structural elements and chromosomal translocations in leukemia.
about
The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesisGenistein induces topoisomerase IIbeta- and proteasome-mediated DNA sequence rearrangements: Implications in infant leukemiaTICdb: a collection of gene-mapped translocation breakpoints in cancerCurrent understanding of the mechanism of benzene-induced leukemia in humans: implications for risk assessmentMMEJ repair of double-strand breaks (director's cut): deleted sequences and alternative endingsThe ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations.Myc dynamically and preferentially relocates to a transcription factory occupied by IghSignatures of selection in fusion transcripts resulting from chromosomal translocations in human cancerMechanism of genomic instability in cells infected with the high-risk human papillomaviruses.Runx1 stabilizes the mammary epithelial cell phenotype and prevents epithelial to mesenchymal transition.The aberrant asynchronous replication - characterizing lymphocytes of cancer patients - is erased following stem cell transplantationRequirement for Parp-1 and DNA ligases 1 or 3 but not of Xrcc1 in chromosomal translocation formation by backup end joining.A novel spliced fusion of MLL with CT45A2 in a pediatric biphenotypic acute leukemia.ATM modulates the loading of recombination proteins onto a chromosomal translocation breakpoint hotspot.Evaluating translocation gene fusions by SNP array data.Molecular analysis of t(15;17) genomic breakpoints in secondary acute promyelocytic leukemia arising after treatment of multiple sclerosisCUX1, a haploinsufficient tumour suppressor gene overexpressed in advanced cancers.The landscape of somatic mutations in infant MLL-rearranged acute lymphoblastic leukemiasCis-regulatory elements are harbored in Intron5 of the RUNX1 gene.Tandem repeats and G-rich sequences are enriched at human CNV breakpointsMolecular pathogenesis of secondary acute promyelocytic leukemiaIdentification of functional cooperative mutations of SETD2 in human acute leukemia.An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathwayECSASB2 mediates MLL degradation during hematopoietic differentiationCytokine-independent growth and clonal expansion of a primary human CD8+ T-cell clone following retroviral transduction with the IL-15 gene.Histone modifications predispose genome regions to breakage and translocation.Stress hematopoiesis reveals abnormal control of self-renewal, lineage bias, and myeloid differentiation in Mll partial tandem duplication (Mll-PTD) hematopoietic stem/progenitor cellsDNA polymerases δ and λ cooperate in repairing double-strand breaks by microhomology-mediated end-joining in Saccharomyces cerevisiaeFaithful after break-up: suppression of chromosomal translocations.MiR-495 is a tumor-suppressor microRNA down-regulated in MLL-rearranged leukemia.PARP1 is required for chromosomal translocations.MYST opportunities for growth control: yeast genes illuminate human cancer gene functions.TAD disruption as oncogenic driver.The PHD fingers of MLL block MLL fusion protein-mediated transformationGenetics of therapy-related myelodysplasia and acute myeloid leukemia.Induction of genetic instability by gain-of-function p53 cancer mutants.DNA structure-induced genomic instability in vivo.Mechanisms of leukemia translocationsCharacterization of human epigenomes.Genomic analysis reveals few genetic alterations in pediatric acute myeloid leukemia
P2860
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P2860
Chromatin structural elements and chromosomal translocations in leukemia.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Chromatin structural elements and chromosomal translocations in leukemia.
@ast
Chromatin structural elements and chromosomal translocations in leukemia.
@en
type
label
Chromatin structural elements and chromosomal translocations in leukemia.
@ast
Chromatin structural elements and chromosomal translocations in leukemia.
@en
prefLabel
Chromatin structural elements and chromosomal translocations in leukemia.
@ast
Chromatin structural elements and chromosomal translocations in leukemia.
@en
P1433
P1476
Chromatin structural elements and chromosomal translocations in leukemia.
@en
P2093
Janet D Rowley
Yanming Zhang
P304
P356
10.1016/J.DNAREP.2006.05.020
P577
2006-08-07T00:00:00Z