Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts.
about
Restriction beyond the restriction point: mitogen requirement for G2 passageRb induces a proliferative arrest and curtails Brn-2 expression in retinoblastoma cellsCyclin E2, a novel G1 cyclin that binds Cdk2 and is aberrantly expressed in human cancersCloning and characterization of a novel Kruppel-associated box family transcriptional repressor that interacts with the retinoblastoma gene product, RBIdentification of a novel E2F3 product suggests a mechanism for determining specificity of repression by Rb proteinsArrest of G(1)-S progression by the p53-inducible gene PC3 is Rb dependent and relies on the inhibition of cyclin D1 transcriptionThe N-terminal 24 amino acids of the p55 gamma regulatory subunit of phosphoinositide 3-kinase binds Rb and induces cell cycle arrestCDC25A phosphatase is a target of E2F and is required for efficient E2F-induced S phasePAM14, a novel MRG- and Rb-associated protein, is not required for development and T-cell function in miceControl of cell cycle progression by c-Jun is p53 dependentE2f3 is critical for normal cellular proliferationInduction of S-phase entry by E2F transcription factors depends on their nuclear localizationInteraction of D-type cyclins with a novel myb-like transcription factor, DMP1Differential role of RB in response to UV and IR damage.Network calisthenics: control of E2F dynamics in cell cycle entryGene expression and cell cycle arrest mediated by transcription factor DMP1 is antagonized by D-type cyclins through a cyclin-dependent-kinase-independent mechanismRibosomal protein L24 defect in belly spot and tail (Bst), a mouse MinuteThe p53-dependent effects of macrophage migration inhibitory factor revealed by gene targetingRB-dependent S-phase response to DNA damageEffects of p21(Cip1/Waf1) at both the G1/S and the G2/M cell cycle transitions: pRb is a critical determinant in blocking DNA replication and in preventing endoreduplicationRetinoblastoma protein contains a C-terminal motif that targets it for phosphorylation by cyclin-cdk complexesCell size checkpoint control by the retinoblastoma tumor suppressor pathwayThe retinoblastoma tumor-suppressor gene, the exception that proves the ruleEndogenous E2F-1 promotes timely G0 exit of resting mouse embryo fibroblasts.The role of c-myc in cellular growth control.Regulation of exit from quiescence by p27 and cyclin D1-CDK4.Strain-dependent myeloid hyperplasia, growth deficiency, and accelerated cell cycle in mice lacking the Rb-related p107 gene.Cell cycle regulators: mechanisms and their role in aetiology, prognosis, and treatment of cancer.MrgX is not essential for cell growth and development in the mouse.A novel function of adenovirus E1A is required to overcome growth arrest by the CDK2 inhibitor p27(Kip1).Timing of cyclin E gene expression depends on the regulated association of a bipartite repressor element with a novel E2F complex.Expression of cyclins E1 and E2 during mouse development and in neoplasiaMitotic chromosome condensation mediated by the retinoblastoma protein is tumor-suppressiveSerum-induced expression of the cdc25A gene by relief of E2F-mediated repressionp53-mediated DNA repair responses to UV radiation: studies of mouse cells lacking p53, p21, and/or gadd45 genes.Tailoring to RB: tumour suppressor status and therapeutic response.Disruption of the G1/S transition in human papillomavirus type 16 E7-expressing human cells is associated with altered regulation of cyclin ERetinoblastoma protein and MyoD function together to effect the repression of Fra-1 and in turn cyclin D1 during terminal cell cycle arrest associated with myogenesis.Mouse Rad9b is essential for embryonic development and promotes resistance to DNA damageElevated poly-(ADP-ribose)-polymerase activity sensitizes retinoblastoma-deficient cells to DNA damage-induced necrosis
P2860
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P2860
Altered cell cycle kinetics, gene expression, and G1 restriction point regulation in Rb-deficient fibroblasts.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Altered cell cycle kinetics, g ...... n in Rb-deficient fibroblasts.
@ast
Altered cell cycle kinetics, g ...... n in Rb-deficient fibroblasts.
@en
type
label
Altered cell cycle kinetics, g ...... n in Rb-deficient fibroblasts.
@ast
Altered cell cycle kinetics, g ...... n in Rb-deficient fibroblasts.
@en
prefLabel
Altered cell cycle kinetics, g ...... n in Rb-deficient fibroblasts.
@ast
Altered cell cycle kinetics, g ...... n in Rb-deficient fibroblasts.
@en
P2093
P2860
P356
P1476
Altered cell cycle kinetics, g ...... n in Rb-deficient fibroblasts.
@en
P2093
P2860
P304
P356
10.1128/MCB.16.5.2402
P407
P577
1996-05-01T00:00:00Z