β-Cell failure in type 2 diabetes: a case of asking too much of too few? - Wikidata - wikimedia - TriplyDB

β-Cell failure in type 2 diabetes: a case of asking too much of too few?

β-Cell failure in type 2 diabetes: a case of asking too much of too few?

http://www.wikidata.org/entity/Q36560568

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Cellular senescence in aging and age-related disease: from mechanisms to therapy β-cell dysfunction: Its critical role in prevention and management of type 2 diabetes.UCHL1 deficiency exacerbates human islet amyloid polypeptide toxicity in β-cells: evidence of interplay between the ubiquitin/proteasome system and autophagy Chaperones ameliorate beta cell dysfunction associated with human islet amyloid polypeptide overexpression Monoconjugation of Human Amylin with Methylpolyethyleneglycol Coordinated Actions of FXR and LXR in Metabolism: From Pathogenesis to Pharmacological Targets for Type 2 Diabetes Reversible changes in pancreatic islet structure and function produced by elevated blood glucose.Abnormal infant islet morphology precedes insulin resistance in PCOS-like monkeys Proinsulin misfolding and endoplasmic reticulum stress during the development and progression of diabetes.Circulating interleukin-1β promotes endoplasmic reticulum stress-induced myocytes apoptosis in diabetic cardiomyopathy via interleukin-1 receptor-associated kinase-2 Type 2 diabetes as a protein misfolding disease.Insulin demand regulates β cell number via the unfolded protein response.Chronic Glucose Exposure Systematically Shifts the Oscillatory Threshold of Mouse Islets: Experimental Evidence for an Early Intrinsic Mechanism of Compensation for Hyperglycemia.Prenatal Testosterone Exposure Leads to Gonadal Hormone-Dependent Hyperinsulinemia and Gonadal Hormone-Independent Glucose Intolerance in Adult Male Rat Offspring CHOP Contributes to, But Is Not the Only Mediator of, IAPP Induced β-Cell Apoptosis Trimeprazine increases IRS2 in human islets and promotes pancreatic β cell growth and function in mice β-Cell Deficit in Obese Type 2 Diabetes, a Minor Role of β-Cell Dedifferentiation and Degranulation.Prevalence and Associated Factors of Insulin Resistance in Adults from Maracaibo City, Venezuela.β Cell-specific increased expression of calpastatin prevents diabetes induced by islet amyloid polypeptide toxicity.Stress and the inflammatory process: a major cause of pancreatic cell death in type 2 diabetes.An Exercise-Only Intervention in Obese Fathers Restores Glucose and Insulin Regulation in Conjunction with the Rescue of Pancreatic Islet Cell Morphology and MicroRNA Expression in Male Offspring.Management of the hospitalized patient with type 1 diabetes mellitus.Is autoimmunity or insulin resistance the primary driver of type 1 diabetes?Residual C-peptide in type 1 diabetes: what do we really know?Synopsis on the linkage of Alzheimer's and Parkinson's disease with chronic diseases.How to make insulin-producing pancreatic β cells for diabetes treatment.Circadian variation of the pancreatic islet transcriptome.Effects of berberine and cinnamic acid on palmitic acid-induced intracellular triglyceride accumulation in NIT-1 pancreatic β cells.Human IAPP-induced pancreatic β cell toxicity and its regulation by autophagy.Increased Hormone-Negative Endocrine Cells in the Pancreas in Type 1 Diabetes.Histone deacetylase regulates insulin signaling via two pathways in pancreatic β cells.Non-neural tyrosine hydroxylase, via modulation of endocrine pancreatic precursors, is required for normal development of beta cells in the mouse pancreas Pathways governing development of stem cell-derived pancreatic β cells: lessons from embryogenesis.Dual role of interleukin-1β in islet amyloid formation and its β-cell toxicity: Implications for type 2 diabetes and islet transplantation.Role of Zinc Homeostasis in the Pathogenesis of Diabetes and Obesity.Circadian Etiology of Type 2 Diabetes Mellitus.Amyloid formation reduces protein kinase B phosphorylation in primary islet β-cells which is improved by blocking IL-1β signaling.Kill two birds with one stone: making multi-transgenic pre-diabetes mouse models through insulin resistance and pancreatic apoptosis pathogenesis.Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid.Islet Amyloid in Whole Pancreas Transplants for Type 1 Diabetes Mellitus (DM): Possible Role of Type 2 DM for Graft Failure.

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β-Cell failure in type 2 diabetes: a case of asking too much of too few?

http://www.wikidata.org/entity/Q36560568

description

2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

β-Cell failure in type 2 diabetes: a case of asking too much of too few?

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β-Cell failure in type 2 diabetes: a case of asking too much of too few?

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β-Cell failure in type 2 diabetes: a case of asking too much of too few?

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β-Cell failure in type 2 diabetes: a case of asking too much of too few?

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β-Cell failure in type 2 diabetes: a case of asking too much of too few?

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Aleksey V Matveyenko

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Ralf Langen

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Safia Costes

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Tatyana Gurlo

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P2860

Wolfram syndrome 1 gene negatively regulates ER stress signaling in rodent and human cells

Pancreatic islet cell toxicity of amylin associated with type-2 diabetes mellitus

Islet amyloid in type 2 diabetes, and the toxic oligomer hypothesis

Endoplasmic reticulum stress and type 2 diabetes

Road to ruin: targeting proteins for degradation in the endoplasmic reticulum

Atomic structure of the cross-β spine of islet amyloid polypeptide (amylin)

Atomic View of a Toxic Amyloid Small Oligomer

The ubiquitin system

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance

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10.2337/DB12-1326

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type-2 diabetes

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