Kinase domain of the muscle-specific receptor tyrosine kinase (MuSK) is sufficient for phosphorylation but not clustering of acetylcholine receptors: required role for the MuSK ectodomain?
about
Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junctionA single pulse of agrin triggers a pathway that acts to cluster acetylcholine receptorsDistinct domains of MuSK mediate its abilities to induce and to associate with postsynaptic specializationsCostameric proteins in human skeletal muscle during muscular inactivityAnalysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinaseLRP4 serves as a coreceptor of agrinCrystal structure of the agrin-responsive immunoglobulin-like domains 1 and 2 of the receptor tyrosine kinase MuSKRin-like, a novel regulator of endocytosis, acts as guanine nucleotide exchange factor for Rab5a and Rab22Spatio-temporally regulated expression of receptor tyrosine kinases, mRor1, mRor2, during mouse development: implications in development and function of the nervous systemThe actin-driven movement and formation of acetylcholine receptor clustersInduction of myasthenia by immunization against muscle-specific kinase.STAT3 activation in skeletal muscle links muscle wasting and the acute phase response in cancer cachexia.Formation of the neuromuscular junction. Agrin and its unusual receptors.The agrin/muscle-specific kinase pathway: new targets for autoimmune and genetic disorders at the neuromuscular junction.A mutation causes MuSK reduced sensitivity to agrin and congenital myasthenia.Altered active zones, vesicle pools, nerve terminal conductivity, and morphology during experimental MuSK myasthenia gravisGuanylate cyclase and cyclic GMP-dependent protein kinase regulate agrin signaling at the developing neuromuscular junctionTo muster a cluster: anchoring neurotransmitter receptors at synapses.The FGF receptor-1 tyrosine kinase domain regulates myogenesis but is not sufficient to stimulate proliferation.Seeking long-term relationship: axon and target communicate to organize synaptic differentiation.Molecular control of neuromuscular junction developmentGlobal analysis of muscle-specific kinase signaling by quantitative phosphoproteomics.Musk Kinase Activity is Modulated By A Serine Phosphorylation Site in The Kinase LoopThe formation of complex acetylcholine receptor clusters requires MuSK kinase activity and structural information from the MuSK extracellular domain.Agrin-induced phosphorylation of the acetylcholine receptor regulates cytoskeletal anchoring and clustering.MuSK induces in vivo acetylcholine receptor clusters in a ligand-independent manner.A minigene of neural agrin encoding the laminin-binding and acetylcholine receptor-aggregating domains is sufficient to induce postsynaptic differentiation in muscle fibres.Dual role for calcium in agrin signaling and acetylcholine receptor clustering.The Ig1/2 domain of MuSK binds to muscle surface and is involved in acetylcholine receptor clustering.Novel role for prepatterned nicotinic acetylcholine receptors during myogenesis.Shp2 is dispensable in the formation and maintenance of the neuromuscular junction.Agrin Receptors at the Skeletal Neuromuscular Junction
P2860
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P2860
Kinase domain of the muscle-specific receptor tyrosine kinase (MuSK) is sufficient for phosphorylation but not clustering of acetylcholine receptors: required role for the MuSK ectodomain?
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Kinase domain of the muscle-sp ...... role for the MuSK ectodomain?
@ast
Kinase domain of the muscle-sp ...... role for the MuSK ectodomain?
@en
type
label
Kinase domain of the muscle-sp ...... role for the MuSK ectodomain?
@ast
Kinase domain of the muscle-sp ...... role for the MuSK ectodomain?
@en
prefLabel
Kinase domain of the muscle-sp ...... role for the MuSK ectodomain?
@ast
Kinase domain of the muscle-sp ...... role for the MuSK ectodomain?
@en
P2093
P2860
P356
P1476
Kinase domain of the muscle-sp ...... role for the MuSK ectodomain?
@en
P2093
G D Yancopoulos
T M DeChiara
P2860
P304
P356
10.1073/PNAS.94.16.8848
P407
P577
1997-08-01T00:00:00Z