The NOT, SPT3, and MOT1 genes functionally interact to regulate transcription at core promoters
about
Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits.A human SPT3-TAFII31-GCN5-L acetylase complex distinct from transcription factor IIDCloning and biochemical characterization of TAF-172, a human homolog of yeast Mot1.Cloning of the cDNA for the TATA-binding protein-associated factorII170 subunit of transcription factor B-TFIID reveals homology to global transcription regulators in yeast and DrosophilaNC2alpha interacts with BTAF1 and stimulates its ATP-dependent association with TATA-binding proteinDNA damage and replication stress induced transcription of RNR genes is dependent on the Ccr4-Not complex.Ccr4-Not complex: the control freak of eukaryotic cellsCooperative action of NC2 and Mot1p to regulate TATA-binding protein function across the genomeGenetic evidence supports a role for the yeast CCR4-NOT complex in transcriptional elongation.Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme.The Modifier of Transcription 1 (Mot1) ATPase and Spt16 Histone Chaperone Co-regulate Transcription through Preinitiation Complex Assembly and Nucleosome Organization.A SAGA-independent function of SPT3 mediates transcriptional deregulation in a mutant of the Ccr4-not complex in Saccharomyces cerevisiae.Genome wide expression analysis of the CCR4-NOT complex indicates that it consists of three modules with the NOT module controlling SAGA-responsive genes.BUR1 and BUR2 encode a divergent cyclin-dependent kinase-cyclin complex important for transcription in vivo.Molecular analysis of the SNF2/SWI2 protein family member MOT1, an ATP-driven enzyme that dissociates TATA-binding protein from DNAThe CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5.Regulation of rRNA synthesis by TATA-binding protein-associated factor Mot1.The yeast FACT complex has a role in transcriptional initiation.High-affinity DNA binding by a Mot1p-TBP complex: implications for TAF-independent transcription.Inhibition of TATA-binding protein function by SAGA subunits Spt3 and Spt8 at Gcn4-activated promoters.Mot1 activates and represses transcription by direct, ATPase-dependent mechanisms.Functional antagonism between RNA polymerase II holoenzyme and global negative regulator NC2 in vivo.Molecular genetics of the RNA polymerase II general transcriptional machineryMOT1 can activate basal transcription in vitro by regulating the distribution of TATA binding protein between promoter and nonpromoter sites.MOT1-catalyzed TBP-DNA disruption: uncoupling DNA conformational change and role of upstream DNAOne small step for Mot1; one giant leap for other Swi2/Snf2 enzymes?The dynamic personality of TATA-binding proteinSnf2/Swi2-related ATPase Mot1 drives displacement of TATA-binding protein by gripping DNAThe NC2 repressor is dispensable in yeast mutated for the Sin4p component of the holoenzyme and plays roles similar to Mot1p in vivo.Interplay of positive and negative regulators in transcription initiation by RNA polymerase II holoenzyme.Association of distinct yeast Not2 functional domains with components of Gcn5 histone acetylase and Ccr4 transcriptional regulatory complexes.Mot1 associates with transcriptionally active promoters and inhibits association of NC2 in Saccharomyces cerevisiae.Genetic interactions between Nhp6 and Gcn5 with Mot1 and the Ccr4-Not complex that regulate binding of TATA-binding protein in Saccharomyces cerevisiae.Snf1-dependent and Snf1-independent pathways of constitutive ADH2 expression in Saccharomyces cerevisiae.Evidence for the involvement of the Glc7-Reg1 phosphatase and the Snf1-Snf4 kinase in the regulation of INO1 transcription in Saccharomyces cerevisiaeFunctional interaction of CCR4-NOT proteins with TATAA-binding protein (TBP) and its associated factors in yeast.Multiple functions of the nonconserved N-terminal domain of yeast TATA-binding protein.Functional significance of the TATA element major groove in transcription initiation by RNA polymerase IIGenome-wide transcriptional dependence on conserved regions of Mot1TATA-binding protein mutants that are lethal in the absence of the Nhp6 high-mobility-group protein
P2860
Q22011058-44C1B533-4194-49BB-AEED-8BC835C6CC0BQ24310397-791056E1-5573-428B-ADD3-AAB4355F932BQ24314747-11B6A0E7-E1AE-4595-A0AD-85B8610E2875Q24320216-E2BB2264-A5EC-416E-8F0D-1BD2B354F309Q24561740-E268C25B-4F68-41EB-898B-8593AD649920Q24815044-0D1E6143-FC13-404F-9048-9E0902630E4BQ26823940-D0A155E4-7B3D-4BC7-BC69-3CA2CF3232C0Q27930925-848DFD86-E3D1-450D-A499-8AFF19E779A3Q27930971-C4DD3EE6-E37F-4FD4-9D43-011BE22FFD90Q27931693-1D5E3F9F-9E10-4878-9304-C1B8930DB609Q27932238-1188BA0A-2521-4BF4-AC0F-4089D6C95D96Q27932596-6A30CB69-DEA4-4026-AF94-169835653BBDQ27932886-9F112D1D-3486-4078-8423-9AAE26A29EC0Q27933584-7D2C5A44-3EE5-4593-AAB9-C2F3213281BFQ27933720-CEAEF365-4950-45B3-9590-7E1E9BE4FF08Q27935175-92915CC6-6670-4806-A547-58C8CCB96AF4Q27935201-EC78BDD7-3377-4BF0-88CF-19CA633F6090Q27935544-B7AD48EF-1C89-483E-A654-B51535E2DB40Q27936250-BFBDA964-753D-4E7E-8328-1FC24B257171Q27938704-D08C6837-C9AB-40AD-8D32-111B73F52D64Q27939577-0455E231-6930-4471-A623-6418284BE19AQ27939623-05D00747-14BE-4D15-A852-B038A73FEB8BQ29620260-8059816A-2FEF-420B-9E3F-2276C3B6C469Q30303655-769FE9B5-34CF-497C-BA68-147F431D8A7FQ30307201-3A61248F-5115-4EC0-A56F-5D66699D1DE0Q30425105-E748C1CD-B305-4620-B052-67457A2CE590Q30434842-B2879CDB-36AA-499C-98EE-E8182D01F596Q30439794-49DF343A-DB78-467A-B69B-892D7BC5FC51Q30856928-F3ADA364-0FAA-4191-B6EB-844A70FFB44AQ33775117-664603E1-0DBB-4F7C-9D90-9119D2CF8832Q33890055-0216BF6C-90A6-4177-958B-BDF0CEFDE546Q34286865-C6F5474A-ABF8-4407-94C3-5BB8F0A7FCCEQ34587825-9BF83C79-2AD3-4863-9479-B198A83406D8Q34588677-62EC3FE5-13F5-4803-A1F2-F8E296101868Q34606906-15B9BEB0-5510-4444-BC02-BDA590B27B0BQ34609942-54FC1F18-1135-48A6-AF54-4A64F2454AA5Q34612505-DADC8651-ACEE-41E7-A572-CA784C789FECQ34640455-89D90236-DFBB-4C85-AC87-DDFD2CD93C61Q35096308-03A5D9C7-E881-4E94-9153-2439FD38E4B5Q35127002-0B27577E-D7A6-4401-823C-9692662B7F7B
P2860
The NOT, SPT3, and MOT1 genes functionally interact to regulate transcription at core promoters
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
The NOT, SPT3, and MOT1 genes ...... ranscription at core promoters
@ast
The NOT, SPT3, and MOT1 genes ...... ranscription at core promoters
@en
type
label
The NOT, SPT3, and MOT1 genes ...... ranscription at core promoters
@ast
The NOT, SPT3, and MOT1 genes ...... ranscription at core promoters
@en
prefLabel
The NOT, SPT3, and MOT1 genes ...... ranscription at core promoters
@ast
The NOT, SPT3, and MOT1 genes ...... ranscription at core promoters
@en
P2860
P356
P1476
The NOT, SPT3, and MOT1 genes ...... ranscription at core promoters
@en
P2093
Collart MA
P2860
P304
P356
10.1128/MCB.16.12.6668
P407
P577
1996-12-01T00:00:00Z