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Variations in frequencies of drug resistance in Plasmodium falciparum.

Variations in frequencies of drug resistance in Plasmodium falciparum.

http://www.wikidata.org/entity/Q36567189

about

Recent clinical and molecular insights into emerging artemisinin resistance in Plasmodium falciparum Malaria in the Greater Mekong Subregion: heterogeneity and complexity Declining artesunate-mefloquine efficacy against falciparum malaria on the Cambodia-Thailand border Antimalarial drug resistance Artemisinin and a Series of Novel Endoperoxide Antimalarials Exert Early Effects on Digestive Vacuole Morphology Artemisinin Resistance in Plasmodium falciparum Malaria Comparative whole genome transcriptome analysis of three Plasmodium falciparum strains.Drug targets and mechanisms of resistance in the anaerobic protozoa Spiroindolones, a potent compound class for the treatment of malaria Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria Genome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasites The heat shock protein 90 of Plasmodium falciparum and antimalarial activity of its inhibitor, geldanamycin Concurrence of Plasmodium falciparum dhfr and crt mutations in northern Ghana Assessment of Plasmodium falciparum resistance to ferroquine (SSR97193) in field isolates and in W2 strain under pressure.Global phenotypic screening for antimalarials Resistance mutations at the lipid substrate binding site of Plasmodium falciparum protein farnesyltransferase Structural polymorphism in the promoter ofpfmrp2confersPlasmodium falciparumtolerance to quinoline drugs Genetic architecture of artemisinin-resistant Plasmodium falciparum A systematic map of genetic variation in Plasmodium falciparum Regulatory hotspots in the malaria parasite genome dictate transcriptional variation A genetically hard-wired metabolic transcriptome in Plasmodium falciparum fails to mount protective responses to lethal antifolates Retention and loss of RNA interference pathways in trypanosomatid protozoans Genome wide adaptations of Plasmodium falciparum in response to lumefantrine selective drug pressure In vitro sensitivity of Plasmodium falciparum from China-Myanmar border area to major ACT drugs and polymorphisms in potential target genes Mitotic evolution of Plasmodium falciparum shows a stable core genome but recombination in antigen families Asexual populations of the human malaria parasite, Plasmodium falciparum, use a two-step genomic strategy to acquire accurate, beneficial DNA amplifications Evidence of a Mild Mutator Phenotype in Cambodian Plasmodium falciparum Malaria Parasites Pyrazoleamide compounds are potent antimalarials that target Na+ homeostasis in intraerythrocytic Plasmodium falciparum.Biochemical and functional characterization of Plasmodium falciparum GTP cyclohydrolase I Validation of isoleucine utilization targets in Plasmodium falciparum Topoisomerase II from Human Malaria Parasites: EXPRESSION, PURIFICATION, AND SELECTIVE INHIBITION In vitro adaptation of Plasmodium falciparum reveal variations in cultivability.Gene encoding a deubiquitinating enzyme is mutated in artesunate- and chloroquine-resistant rodent malaria parasites Origin of robustness in generating drug-resistant malaria parasites Shotgun DNA microarrays and stage-specific gene expression in Plasmodium falciparum malaria.Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase.Extreme mutation bias and high AT content in Plasmodium falciparum.In vitro selection of Plasmodium falciparum drug-resistant parasite lines.Plasmodium dihydroorotate dehydrogenase: a promising target for novel anti-malarial chemotherapy.

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P2860

Variations in frequencies of drug resistance in Plasmodium falciparum.

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P2860

Interactions among mutations affecting spontaneous mutation, mitotic recombination, and DNA repair in yeast.

Human malaria parasites in continuous culture

The significance of responses of the genome to challenge

Biochemistry of multidrug resistance mediated by the multidrug transporter

Mefloquine. A review of its antimalarial activity, pharmacokinetic properties and therapeutic efficacy.

Evidence for a switching mechanism in the invasion of erythrocytes by Plasmodium falciparum.

Frequency of drug resistance in Plasmodium falciparum: a nonsynergistic combination of 5-fluoroorotate and atovaquone suppresses in vitro resistance.

Kinetics of Plasmodium falciparum thymidylate synthase: interactions with high-affinity metabolites of 5-fluoroorotate and D1694

Drug resistant malaria, with special reference to Thailand.

Halofantrine. A review of its antimalarial activity, pharmacokinetic properties and therapeutic potential.

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