Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria
about
Recent clinical and molecular insights into emerging artemisinin resistance in Plasmodium falciparumSpiroindolones, a potent compound class for the treatment of malariaGenome scanning of Amazonian Plasmodium falciparum shows subtelomeric instability and clindamycin-resistant parasitesSynthesis and stereochemical determination of an antiparasitic pseudo-aminal type monoterpene indole alkaloidCholine analogues in malaria chemotherapyDrug resistance genomics of the antimalarial drug artemisininPlasmodium falciparum parasites are killed by a transition state analogue of purine nucleoside phosphorylase in a primate animal modelStructure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors with Clinical Candidate PotentialFluorine Modulates Species Selectivity in the Triazolopyrimidine Class of Plasmodium falciparum Dihydroorotate Dehydrogenase InhibitorsPfCRT and its role in antimalarial drug resistanceDiscovery of a novel and conserved Plasmodium falciparum exported protein that is important for adhesion of PfEMP1 at the surface of infected erythrocytesArtemisinin Action and Resistance in Plasmodium falciparumIdentification of a mutant PfCRT-mediated chloroquine tolerance phenotype in Plasmodium falciparumCure of hookworm infection with a cysteine protease inhibitorAnti-plasmodial polyvalent interactions in Artemisia annua L. aqueous extract--possible synergistic and resistance mechanismsEfficacy and safety of dihydroartemisinin-piperaquine for treatment of Plasmodium vivax malaria in endemic countries: meta-analysis of randomized controlled studiesReal-time imaging of the intracellular glutathione redox potential in the malaria parasite Plasmodium falciparumInhibition of Plasmepsin V activity demonstrates its essential role in protein export, PfEMP1 display, and survival of malaria parasitesAbsence of putative artemisinin resistance mutations among Plasmodium falciparum in Sub-Saharan Africa: a molecular epidemiologic studyGenome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in KenyaDesign, Synthesis, and Antiplasmodial Activity of Hybrid Compounds Based on (2R,3S)-N-Benzoyl-3-phenylisoserineIdentification and optimization of an aminoalcohol-carbazole series with antimalarial properties.A Variant PfCRT Isoform Can Contribute to Plasmodium falciparum Resistance to the First-Line Partner Drug PiperaquineEating at the table of another: metabolomics of host-parasite interactions.Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds.Does the Use of Dihydroartemisinin-Piperaquine in Treating Patients with Uncomplicated falciparum Malaria Reduce the Risk for Recurrent New falciparum Infection More Than Artemether-Lumefantrine?Transmembrane segment 11 appears to line the purine permeation pathway of the Plasmodium falciparum equilibrative nucleoside transporter 1 (PfENT1).Cysteamine, the molecule used to treat cystinosis, potentiates the antimalarial efficacy of artemisinin.Diversity-Oriented Synthesis Yields a Novel Lead for the Treatment of Malaria.Fingerprinting the substrate specificity of M1 and M17 aminopeptidases of human malaria, Plasmodium falciparum.Gibberellin biosynthetic inhibitors make human malaria parasite Plasmodium falciparum cells swell and rupture to death.Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporinAltered temporal response of malaria parasites determines differential sensitivity to artemisininReplication of Plasmodium in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance.Spontaneous mutations in the Plasmodium falciparum sarcoplasmic/ endoplasmic reticulum Ca2+-ATPase (PfATP6) gene among geographically widespread parasite populations unexposed to artemisinin-based combination therapies.Use of the atmospheric generators for capnophilic bacteria Genbag-CO2 for the evaluation of in vitro Plasmodium falciparum susceptibility to standard anti-malarial drugs.Ranking of elimination feasibility between malaria-endemic countries.Evidence that mutant PfCRT facilitates the transmission to mosquitoes of chloroquine-treated Plasmodium gametocytesTreating uncomplicated malaria in children: comparing artemisinin-based combination therapies.The antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation- and chemotherapy-induced cell death.
P2860
Q21032477-E90B47D0-F497-484C-8D2B-E3827B61081CQ24606915-F4A5E9B4-F0E1-42F4-B561-40C9686EE868Q24625172-5E939E36-4A02-48F1-82F7-4352EF2CE81EQ26744255-18728A6F-C268-402A-B727-F3115A9DDEF4Q26851323-C485C3A6-F248-47A1-ADDA-AAC9F4E7D77AQ26862789-EEF52300-5878-4A40-B454-72546953E812Q27314759-7796F2CE-9591-45F2-B23A-63165BB7000FQ27670499-CC7A7CB0-79D6-4B94-94DE-B6B1ABE781E3Q27683656-5FCEBF01-4AAF-442B-95F2-BEDA82978C82Q27861957-D2410B0C-8802-4F46-A88D-80E9F0CF78D5Q27974160-C5945640-7065-4EEC-B9B6-979EDB50C265Q28276294-24210B72-3A8A-4720-8FAB-E1801425AF77Q28473923-90E8CA82-8286-4293-BD5E-F57824C45FDDQ28480978-ECBA6EDC-0BAB-4D29-9B48-FF1BD63D32F8Q28535139-400341B8-7A53-43CF-9AB9-B9A3B7C49A4FQ28535686-AA22218D-4DC0-4D2B-955F-C077E41F6DB5Q28536670-6252AC5A-C8B1-4471-B886-99F35616428AQ28540204-D0598715-2C65-46C4-80DD-EE2DF057FE46Q30389796-F0C59509-C221-4381-891B-470B7934AD6FQ31076495-348845C6-C53C-4367-94D3-2AC070D979E0Q33635987-0879D6C8-28BA-4028-B019-669BA86EBFFAQ33636074-7FCFC833-192F-433B-BB3E-FE45EEA19DB5Q33654512-189E23D6-5AA6-437E-ABA6-061B6006EF76Q33671828-AED19BE2-27E8-4AA8-9CA8-7263DE2CA476Q33682916-C573DC9F-7DA8-451F-9AF1-F08A09C0E0E5Q33874069-AA27A86A-37E6-45D7-8BAE-CEF79103F23EQ33883226-377626A3-38C7-47B8-AB61-7D72C38B779FQ34045221-CAB5AEAA-7E01-46C9-B3B7-730A3BB23C16Q34157359-75069009-385D-43FA-987E-4647C6148770Q34168471-483C6B26-4088-416C-947E-F8A4D9FD5160Q34193063-32E80FB5-F3EF-4286-9C88-1A2C566E5315Q34306714-59420BCF-C43D-497C-900C-FC6F9B624835Q34329125-9968C509-78CE-4F86-A9C5-74B018827B9FQ34475026-9CDEA7CE-3971-4287-B368-2AB2D951D01CQ34483513-95B1E7C8-8D3E-456B-AA38-6454884B6655Q34541163-3AFD9216-15A6-4052-9376-79AD8F6EB445Q34605561-3B000C2E-21FF-4F1F-B3E3-A927E372369AQ34763527-ED486AEE-352F-4335-B3E8-5BC0DBC4F917Q35004430-EBC5E0C6-A2FB-46AD-AFC8-D057FAB9CF50Q35013756-28713358-FC89-4F45-93C3-E841D524487F
P2860
Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria
@ast
Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria
@en
Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria
@nl
type
label
Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria
@ast
Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria
@en
Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria
@nl
prefLabel
Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria
@ast
Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria
@en
Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria
@nl
P2860
P3181
P356
P1476
Artemisinin-based combination therapies: a vital tool in efforts to eliminate malaria
@en
P2093
Richard T Eastman
P2860
P2888
P304
P3181
P356
10.1038/NRMICRO2239
P407
P577
2009-12-01T00:00:00Z
P5875
P6179
1023651148