TGFβ-dependent expression of PD-1 and PD-L1 controls CD8(+) T cell anergy in transplant tolerance
about
Anti-CD3 treatment up-regulates programmed cell death protein-1 expression on activated effector T cells and severely impairs their inflammatory capacityProgrammed death-ligand 1 expression at tumor invasive front is associated with epithelial-mesenchymal transition and poor prognosis in esophageal squamous cell carcinoma.Prevention of allograft rejection in heart transplantation through concurrent gene silencing of TLR and Kinase signaling pathways.Blockade of only TGF-β 1 and 2 is sufficient to enhance the efficacy of vaccine and PD-1 checkpoint blockade immunotherapy.Tracking of TCR-Transgenic T Cells Reveals That Multiple Mechanisms Maintain Cardiac Transplant Tolerance in Mice.Immunotherapy of WAP-TNP mice with early stage mammary gland tumors.The Induction and Maintenance of Transplant Tolerance Engages Both Regulatory and Anergic CD4+ T cells.PD-1 expression on CD8+ T cells regulates their differentiation within lung allografts and is critical for tolerance induction.A novel bifunctional anti-PD-L1/TGF-β Trap fusion protein (M7824) efficiently reverts mesenchymalization of human lung cancer cells.Harnessing Apoptotic Cells for Transplantation Tolerance: Current Status and Future Perspectives.MHC-mismatched mixed chimerism restores peripheral tolerance of noncross-reactive autoreactive T cells in NOD mice.Oral histone deacetylase inhibitor synergises with T cell targeted immunotherapy to preserve beta cell metabolic function and induce stable remission of new-onset autoimmune diabetes in NOD mice.PD-L1 serves as a double agent in separating GVL from GVHD.SATB1 Expression Governs Epigenetic Repression of PD-1 in Tumor-Reactive T Cells.Mechanisms of Mixed Chimerism-Based Transplant Tolerance.Interferon-gamma drives programmed death-ligand 1 expression on islet β cells to limit T cell function during autoimmune diabetes.Future of anti-PD-1/PD-L1 applications: Combinations with other therapeutic regimens.Non-Invasive Multiphoton Imaging of Islets Transplanted Into the Pinna of the NOD Mouse Ear Reveals the Immediate Effect of Anti-CD3 Treatment in Autoimmune Diabetes.Single-cell transcriptomics reveal that PD-1 mediates immune tolerance by regulating proliferation of regulatory T cellsBiomarkers for predicting efficacy of PD-1/PD-L1 inhibitorsThe Emerging Role of CD8 Tissue Resident Memory T (T) Cells in Antitumor Immunity: A Unique Functional Contribution of the CD103 Integrin
P2860
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P2860
TGFβ-dependent expression of PD-1 and PD-L1 controls CD8(+) T cell anergy in transplant tolerance
description
2016 nî lūn-bûn
@nan
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
2016年论文
@zh
2016年论文
@zh-cn
name
TGFβ-dependent expression of P ...... anergy in transplant tolerance
@ast
TGFβ-dependent expression of P ...... anergy in transplant tolerance
@en
type
label
TGFβ-dependent expression of P ...... anergy in transplant tolerance
@ast
TGFβ-dependent expression of P ...... anergy in transplant tolerance
@en
prefLabel
TGFβ-dependent expression of P ...... anergy in transplant tolerance
@ast
TGFβ-dependent expression of P ...... anergy in transplant tolerance
@en
P2093
P2860
P50
P356
P1433
P1476
TGFβ-dependent expression of P ...... anergy in transplant tolerance
@en
P2093
Alix Besançon
Benedita Rocha
Emmanuelle Waeckel-Enée
Fabrice Valette
Hans-Dieter Volk
Hideo Yagita
Marije Baas
Tania Goncalves
P2860
P304
P356
10.7554/ELIFE.08133
P407
P577
2016-01-29T00:00:00Z