T-bet and Eomes are differentially linked to the exhausted phenotype of CD8+ T cells in HIV infection
about
Effector, Memory, and Dysfunctional CD8(+) T Cell Fates in the Antitumor Immune ResponseTargeting Transcriptional Regulators of CD8+ T Cell Dysfunction to Boost Anti-Tumor ImmunityMolecular and cellular insights into T cell exhaustionMolecular characterization of HCMV-specific immune responses: Parallels between CD8(+) T cells, CD4(+) T cells, and NK cellsOvercoming T cell exhaustion in infection and cancerThe PD1:PD-L1/2 Pathway from Discovery to Clinical ImplementationInnate and Adaptive Immune Regulation During Chronic Viral InfectionsBlimp-1-mediated CD4 T cell exhaustion causes CD8 T cell dysfunction during chronic toxoplasmosis.Infection history determines the differentiation state of human CD8+ T cellsInhibitory Receptors Beyond T Cell Exhaustion.Multidimensional Clusters of CD4+ T Cell Dysfunction Are Primarily Associated with the CD4/CD8 Ratio in Chronic HIV InfectionInitiation of Antiretroviral Therapy (ART) at Different Stages of HIV-1 Disease Is Not Associated with the Proportion of Exhausted CD8+ T CellsCD39 Expression Identifies Terminally Exhausted CD8+ T CellsGenetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cellsDifferential Impact of In Vivo CD8+ T Lymphocyte Depletion in Controller versus Progressor Simian Immunodeficiency Virus-Infected Macaques.Exhaustion of Activated CD8 T Cells Predicts Disease Progression in Primary HIV-1 Infection.Temporal Dynamics of CD8+ T Cell Effector Responses during Primary HIV Infection.Bortezomib enhances expression of effector molecules in anti-tumor CD8+ T lymphocytes by promoting Notch-nuclear factor-κB crosstalk.TGFβ-dependent expression of PD-1 and PD-L1 controls CD8(+) T cell anergy in transplant toleranceCostimulatory and Coinhibitory Receptor Pathways in Infectious DiseaseElevated levels of invariant natural killer T-cell and natural killer cell activation correlate with disease progression in HIV-1 and HIV-2 infections.Clonal Abundance of Tumor-Specific CD4(+) T Cells Potentiates Efficacy and Alters Susceptibility to ExhaustionCD4+ T cells with an activated and exhausted phenotype distinguish immunodeficiency during aviremic HIV-2 infection.Perturbed CD8+ T cell TIGIT/CD226/PVR axis despite early initiation of antiretroviral treatment in HIV infected individuals.Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus.Ageing and latent CMV infection impact on maturation, differentiation and exhaustion profiles of T-cell receptor gammadelta T-cellsCo-inhibitory blockade while preserving tolerance: checkpoint inhibitors for glioblastoma.PSGL-1: A New Player in the Immune Checkpoint Landscape.Transcriptional and epigenetic regulation of T cell hyporesponsiveness.Molecular Dissection of CD8+ T-Cell Dysfunction.IL-21 Receptor Signaling Is Essential for Optimal CD4+ T Cell Function and Control of Mycobacterium tuberculosis Infection in Mice.The Transcription Factor NFAT1 Participates in the Induction of CD4+ T Cell Functional Exhaustion during Plasmodium yoelii Infection.TCF1+ hepatitis C virus-specific CD8+ T cells are maintained after cessation of chronic antigen stimulation.The Balance between CD8+ T Cell-Mediated Clearance of AAV-Encoded Antigen in the Liver and Tolerance Is Dependent on the Vector Dose.Exhaustion-associated regulatory regions in CD8+ tumor-infiltrating T cells.HLA-G+ HIV-1-specific CD8+ T cells are associated with HIV-1 immune control.Apoptotic Epitope-Specific CD8+ T Cells and Interferon Signaling Intersect in Chronic Hepatitis C Virus Infection.mTOR Modulates Lymphocyte Differentiation through T-bet and Eomesodermin in Response to Invasive Pulmonary Aspergillosis in Rats.Fine-tuning of CD8(+) T-cell effector functions by targeting the 2B4-CD48 interaction.HIV-TB coinfection impairs CD8(+) T-cell differentiation and function while dehydroepiandrosterone improves cytotoxic antitubercular immune responses.
P2860
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P2860
T-bet and Eomes are differentially linked to the exhausted phenotype of CD8+ T cells in HIV infection
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2014 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2014 թվականի հուլիսին հրատարակված գիտական հոդված
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2014年の論文
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T-bet and Eomes are differenti ...... CD8+ T cells in HIV infection
@ast
T-bet and Eomes are differenti ...... CD8+ T cells in HIV infection
@en
type
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T-bet and Eomes are differenti ...... CD8+ T cells in HIV infection
@ast
T-bet and Eomes are differenti ...... CD8+ T cells in HIV infection
@en
prefLabel
T-bet and Eomes are differenti ...... CD8+ T cells in HIV infection
@ast
T-bet and Eomes are differenti ...... CD8+ T cells in HIV infection
@en
P2093
P2860
P50
P1433
P1476
T-bet and Eomes are differenti ...... CD8+ T cells in HIV infection
@en
P2093
Annika C Karlsson
Bo Hejdeman
Jakob Michaëlsson
Juliet Frederiksen
Martin A Ivarsson
Michael R Betts
Richard A Koup
P2860
P304
P356
10.1371/JOURNAL.PPAT.1004251
P577
2014-07-17T00:00:00Z