Reduction of mutant ataxin-7 expression restores motor function and prevents cerebellar synaptic reorganization in a conditional mouse model of SCA7 - Wikidata - wikimedia - TriplyDB

Reduction of mutant ataxin-7 expression restores motor function and prevents cerebellar synaptic reorganization in a conditional mouse model of SCA7

Reduction of mutant ataxin-7 expression restores motor function and prevents cerebellar synaptic reorganization in a conditional mouse model of SCA7

http://www.wikidata.org/entity/Q36580728

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Experimental neurotransplantation treatment for hereditary cerebellar ataxias Oligonucleotide-based strategies to combat polyglutamine diseases.Climbing fiber-Purkinje cell synaptic pathology in tremor and cerebellar degenerative diseases.Pulling complexes out of complex diseases: Spinocerebellar Ataxia 7.The ubiquitin-proteasome system in neurodegenerative diseases: precipitating factor, yet part of the solution Transplantation and Stem Cell Therapy for Cerebellar Degenerations.Abnormal climbing fibre-Purkinje cell synaptic connections in the essential tremor cerebellum.RNA interference-based therapy for spinocerebellar ataxia type 7 retinal degeneration.Nonallele specific silencing of ataxin-7 improves disease phenotypes in a mouse model of SCA7.Mutant CAG Repeats Effectively Targeted by RNA Interference in SCA7 Cells.Functions of SAGA in development and disease.From mice to men: lessons from mutant ataxic mice.An understanding of spinocerebellar ataxia.Elevated mutant dynorphin A causes Purkinje cell loss and motor dysfunction in spinocerebellar ataxia type 23.MULTIMODAL IMAGING OF A FAMILY WITH SPINOCEREBELLAR ATAXIA TYPE 7 DEMONSTRATING PHENOTYPIC VARIATION AND PROGRESSION OF RETINAL DEGENERATION.Amyotrophic Lateral Sclerosis: An Aging-Related Disease

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Reduction of mutant ataxin-7 expression restores motor function and prevents cerebellar synaptic reorganization in a conditional mouse model of SCA7

http://www.wikidata.org/entity/Q36580728

description

2012 nî lūn-bûn

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Reduction of mutant ataxin-7 e ...... onditional mouse model of SCA7

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Reduction of mutant ataxin-7 e ...... onditional mouse model of SCA7

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Reduction of mutant ataxin-7 e ...... onditional mouse model of SCA7

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Human Molecular Genetics

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Reduction of mutant ataxin-7 e ...... onditional mouse model of SCA7

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Albert R La Spada

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Bryce L Sopher

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Gwenn A Garden

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Kien-Thiet Nguyen

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Mathini S Mohanachandran

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Sarah M Waldherr

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Stephanie A Furrer

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Travis D Baughn

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Vincent A Damian

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P2860

Mitochondrial dysfunction in NnaD mutant flies and Purkinje cell degeneration mice reveals a role for Nna proteins in neuronal bioenergetics

Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease

Trinucleotide Repeat Disorders

Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse

SCA1-like disease in mice expressing wild-type ataxin-1 with a serine to aspartic acid replacement at residue 776.

PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function.

Molecular pathogenesis and cellular pathology of spinocerebellar ataxia type 7 neurodegeneration

Glial S100B protein modulates mutant ataxin-1 aggregation and toxicity: TRTK12 peptide, a potential candidate for SCA1 therapy

Abnormalities in the climbing fiber-Purkinje cell circuitry contribute to neuronal dysfunction in ATXN1[82Q] mice

Neurotoxic protein oligomerisation associated with polyglutamine diseases.

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10.1093/HMG/DDS495

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5

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22

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2012-11-29T00:00:00Z

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233806354

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23197655

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3561911

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