Bak apoptotic function is not directly regulated by phosphorylation.
about
Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosisApoptotic pore formation is associated with in-plane insertion of Bak or Bax central helices into the mitochondrial outer membraneBid chimeras indicate that most BH3-only proteins can directly activate Bak and Bax, and show no preference for Bak versus Bax.Dissociation of Bak α1 helix from the core and latch domains is required for apoptosis.Disordered clusters of Bak dimers rupture mitochondria during apoptosis.Bak apoptotic pores involve a flexible C-terminal region and juxtaposition of the C-terminal transmembrane domains.Mcl-1 and Bcl-xL sequestration of Bak confers differential resistance to BH3-only proteins.
P2860
Q28300914-9454C869-4CAE-456C-B366-54990EB97D0FQ34314503-6FC07A58-49BD-4AC9-B4E5-B344694A17CDQ36293251-8F8AD87A-B03D-4A48-83B1-55E4B7E65A02Q38886445-0AF15A49-58EF-44E9-B5B4-E540234C9A41Q38969426-39EDAF0B-FE82-4B5F-A170-590A8E6A7D53Q43156404-7896B386-0248-4125-A909-DCC195D65A27Q49830082-2CE2C8F0-074C-40A9-9775-778C1B98BB00
P2860
Bak apoptotic function is not directly regulated by phosphorylation.
description
2013 nî lūn-bûn
@nan
2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
@zh-tw
2013年论文
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2013年论文
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2013年论文
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name
Bak apoptotic function is not directly regulated by phosphorylation.
@ast
Bak apoptotic function is not directly regulated by phosphorylation.
@en
type
label
Bak apoptotic function is not directly regulated by phosphorylation.
@ast
Bak apoptotic function is not directly regulated by phosphorylation.
@en
prefLabel
Bak apoptotic function is not directly regulated by phosphorylation.
@ast
Bak apoptotic function is not directly regulated by phosphorylation.
@en
P2093
P2860
P356
P1476
Bak apoptotic function is not directly regulated by phosphorylation.
@en
P2093
P2860
P2888
P356
10.1038/CDDIS.2012.191
P577
2013-01-10T00:00:00Z
P5875
P6179
1005146376