Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis
about
BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition poretBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome cTumor necrosis factor-alpha induces Bax-Bak interaction and apoptosis, which is inhibited by adenovirus E1B 19KBAK multimerization for apoptosis, but not bid binding, is inhibited by negatively charged residue in the BAK hydrophobic grooveEndoplasmic reticulum stress-induced apoptosis: multiple pathways and activation of p53-up-regulated modulator of apoptosis (PUMA) and NOXA by p53Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.Heterodimerization of BAK and MCL-1 activated by detergent micellesBH3 domains other than Bim and Bid can directly activate Bax/BakHSpin1, a transmembrane protein interacting with Bcl-2/Bcl-xL, induces a caspase-independent autophagic cell deathThe vaccinia virus protein F1L interacts with Bim and inhibits activation of the pro-apoptotic protein BaxThe tyrosine kinase Lck is a positive regulator of the mitochondrial apoptosis pathway by controlling Bak expressionMitochondrial carrier homolog 2 is a target of tBID in cells signaled to die by tumor necrosis factor alpha.Loss of Bif-1 suppresses Bax/Bak conformational change and mitochondrial apoptosisChlamydia inhibit host cell apoptosis by degradation of proapoptotic BH3-only proteinsIdentification of a novel topoisomerase inhibitor effective in cells overexpressing drug efflux transportersThe mitochondrial fission protein hFis1 requires the endoplasmic reticulum gateway to induce apoptosisThe role of BH3-mimetic drugs in the treatment of pediatric hepatoblastomaStructural Insight into BH3 Domain Binding of Vaccinia Virus Antiapoptotic F1LBuilding blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosisDamage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate.Mono- or double-site phosphorylation distinctly regulates the proapoptotic function of BaxBax activation initiates the assembly of a multimeric catalyst that facilitates Bax pore formation in mitochondrial outer membranesSpatial and temporal changes in Bax subcellular localization during anoikisThe mitochondrial protein Bak is pivotal for gliotoxin-induced apoptosis and a critical host factor of Aspergillus fumigatus virulence in miceEvaluating cytochrome c diffusion in the intermembrane spaces of mitochondria during cytochrome c releaseBax and Bak can localize to the endoplasmic reticulum to initiate apoptosisBid induces the oligomerization and insertion of Bax into the outer mitochondrial membraneProteomic analysis of apoptosis initiation induced by all-trans retinoic acid in human acute promyelocytic leukemia cells.Study of apoptosis in human liver cancers.Charting calcium-regulated apoptosis pathways using chemical biology: role of calmodulin kinase IIDynamical systems analysis of mitochondrial BAK activation kinetics predicts resistance to BH3 domains.Escherichia coli subtilase cytotoxin induces apoptosis regulated by host Bcl-2 family proteins Bax/Bak.Degradation of the proapoptotic proteins Bik, Puma, and Bim with Bcl-2 domain 3 homology in Chlamydia trachomatis-infected cells.Mcl-1 promotes survival of thymocytes by inhibition of Bak in a pathway separate from Bcl-2.Overexpression of mcl-1 attenuates liver injury and fibrosis in the bile duct-ligated mouse.Post-cytochrome C protection from apoptosis conferred by a MAPK pathway in Xenopus egg extractsApoptosis in the vasculature: mechanisms and functional importance.Regulation of mitochondrial apoptotic events by p53-mediated disruption of complexes between antiapoptotic Bcl-2 members and Bim.Bid, a widely expressed proapoptotic protein of the Bcl-2 family, displays lipid transfer activity.Noxa mediates hepatic stellate cell apoptosis by proteasome inhibition.
P2860
Q22254597-635843F3-D007-4FD1-88B3-F3ED6B91EEC5Q24290118-18540266-895A-48D7-92C9-281E401CF74DQ24291723-9224333C-433D-417A-97B7-5C08B15B7B42Q24295530-92206831-8394-4BCF-AEB2-1E88CB91A8E4Q24300781-34910D32-188B-4461-8AD1-9B83ADCB035BQ24302494-4328A7E0-F633-49C3-AB6D-9B7413A58949Q24305060-9C0C8C31-1E03-473F-AC07-48406EDFB5A2Q24305138-E31FFA0E-A619-4EBC-9398-58DBC9BCD372Q24305591-918B4016-D22B-41A5-A291-41A4ACA6D2E9Q24310440-BD325FD0-19A0-4A48-A619-357C9E6722CCQ24317331-4AA5065F-75D4-44CE-8BBD-433F7F2A459EQ24529078-4499C8E2-567B-4908-8129-0324F7007EDBQ24534937-AA644001-D163-42EB-86A9-2B49856EC983Q24645975-D43C36AD-7DC0-4E63-A0BF-A756C2DBE09BQ24648348-64191AFF-3713-4128-8196-927E040B8011Q24673883-898D1872-2CE9-456C-B02C-D8BBC8ACF9CDQ26827928-AE9CF474-A5DC-428A-8AF4-7FCC0D9C246BQ27683883-C36E0BA2-DE2C-4B07-AF59-35BE131C8566Q28300914-601F6E1F-DC60-4D0D-8765-6C64BFDD9BAFQ28364008-9F8E38BF-E156-4CF7-80FD-19FB80A940EDQ28475783-5C181EB1-0813-4F27-8B8F-2AF6D04AF132Q28483986-96DBC993-24A8-4C00-B922-99804F623475Q28507532-A2CEA2B3-0BFC-4BC4-AE57-1988769A58DFQ28511677-EAB5AE39-AB68-4A21-BBEF-A8B2195FBA80Q28569153-BA91BBEB-E2CD-48B8-A21F-D8F51185EE90Q28588618-6D5420B7-8481-4231-93C4-7ED350F01B18Q28647586-72B8344B-1337-4BAC-90E2-2FBE8AE10B2BQ30724109-5D238618-2A86-4D7F-8229-E7B6568A50D2Q31046923-48F375D1-06C6-4E2A-9209-6FBDDFB83FE4Q33357029-1A140E27-EE3E-44B9-945A-B9B2AD2ADA1FQ33363105-666E50A3-41EA-4413-8039-6AED47A4861FQ33659904-AE3C9C83-45F1-4E29-82BE-6D1EF63BF478Q33716144-CD5D3ED2-B6D0-4178-8CF3-AFD00B206464Q33838448-F0A7DAE2-A282-4114-97AA-8CFF44A19C13Q33889618-FDBE4B62-86DE-45A5-8007-ECFA22AAB76FQ33953642-5F668790-EEC7-4E73-BDE5-B58EEA2C47FAQ33959479-9757428B-5688-40FC-9BF6-98EBFCCE64E0Q33990989-47F5D163-200B-4950-B151-21D217B04D3BQ34012615-304D3A85-187E-43FF-AB4B-6804F5686B89Q34070935-2EC38D54-25FE-4F6F-9E92-02BB10FCF6AB
P2860
Cell damage-induced conformational changes of the pro-apoptotic protein Bak in vivo precede the onset of apoptosis
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Cell damage-induced conformati ...... precede the onset of apoptosis
@ast
Cell damage-induced conformati ...... precede the onset of apoptosis
@en
Cell damage-induced conformati ...... precede the onset of apoptosis
@nl
type
label
Cell damage-induced conformati ...... precede the onset of apoptosis
@ast
Cell damage-induced conformati ...... precede the onset of apoptosis
@en
Cell damage-induced conformati ...... precede the onset of apoptosis
@nl
prefLabel
Cell damage-induced conformati ...... precede the onset of apoptosis
@ast
Cell damage-induced conformati ...... precede the onset of apoptosis
@en
Cell damage-induced conformati ...... precede the onset of apoptosis
@nl
P2093
P2860
P356
P1476
Cell damage-induced conformati ...... precede the onset of apoptosis
@en
P2093
C P Morgan
G J Griffiths
J A Hickman
J Whitehouse
P2860
P304
P356
10.1083/JCB.144.5.903
P407
P577
1999-03-08T00:00:00Z