The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition.
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Three decades of beta-lactamase inhibitorsDesign and Exploration of Novel Boronic Acid Inhibitors Reveals Important Interactions with a Clavulanic Acid-Resistant Sulfhydryl-Variable (SHV) β-LactamasePenam Sulfones and β-Lactamase Inhibition: SA2-13 and the Importance of the C2 Side Chain Length and CompositionEnzymatic analysis of the effect of naturally occurring Leu138Pro mutation identified in SHV β-lactamase on hydrolysis of penicillin and ampicillin.Role of SHV β-lactamase variants in resistance of clinical Klebsiella pneumoniae strains to β-lactams in an Algerian hospital.Combinatorial active-site variants confer sustained clavulanate resistance in BlaC β-lactamase from Mycobacterium tuberculosis.Characterization of the inhibitor-resistant SHV β-lactamase SHV-107 in a clinical Klebsiella pneumoniae strain coproducing GES-7 enzyme.The evolutionary histories of clinical and environmental SHV β-lactamases are intertwinedDetection of resistance to beta-lactamase inhibitors in strains with CTX-M beta-lactamases: a multicenter external proficiency study using a well-defined collection of Escherichia coli strains.In vitro selection of variants resistant to beta-lactams plus beta-lactamase inhibitors in CTX-M beta-lactamases: predicting the in vivo scenario?Homology modeling and virtual screening of inhibitors against TEM- and SHV-type-resistant mutants: A multilayer filtering approach.Substitutions at position 105 in SHV family β-lactamases decrease catalytic efficiency and cause inhibitor resistance.Biochemical study of a new inhibitor-resistant beta-lactamase, SHV-84, produced by a clinical Escherichia coli strain.Biochemical characterization of SHV-55, an extended-spectrum class A beta-lactamase from Klebsiella pneumoniae.
P2860
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P2860
The Lys234Arg substitution in the enzyme SHV-72 is a determinant for resistance to clavulanic acid inhibition.
description
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2008年の論文
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2008年論文
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2008年論文
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2008年論文
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2008年論文
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2008年論文
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name
The Lys234Arg substitution in ...... to clavulanic acid inhibition.
@ast
The Lys234Arg substitution in ...... to clavulanic acid inhibition.
@en
type
label
The Lys234Arg substitution in ...... to clavulanic acid inhibition.
@ast
The Lys234Arg substitution in ...... to clavulanic acid inhibition.
@en
prefLabel
The Lys234Arg substitution in ...... to clavulanic acid inhibition.
@ast
The Lys234Arg substitution in ...... to clavulanic acid inhibition.
@en
P2093
P2860
P50
P356
P1476
The Lys234Arg substitution in ...... to clavulanic acid inhibition
@en
P2093
Frédéric Robin
M José Salgado
Richard Bonnet
P2860
P304
P356
10.1128/AAC.01381-07
P407
P577
2008-03-03T00:00:00Z