Clearance of amyloid-beta in Alzheimer's disease: progress, problems and perspectives.
about
Mechanisms of U87 astrocytoma cell uptake and trafficking of monomeric versus protofibril Alzheimer's disease amyloid-β proteinsTransthyretin protects against A-beta peptide toxicity by proteolytic cleavage of the peptide: a mechanism sensitive to the Kunitz protease inhibitor.Selective modulation of amyloid-beta peptide degradation by flurbiprofen, fenofibrate, and related compounds regulates Abeta levels.Alteration of Aβ metabolism-related molecules in predementia induced by AlCl3 and D-galactoseEffects of (-)Epicatechin on the Pathology of APP/PS1 Transgenic MiceProtective role of S-nitrosoglutathione (GSNO) against cognitive impairment in rat model of chronic cerebral hypoperfusion.Iowa variant of familial Alzheimer's disease: accumulation of posttranslationally modified AbetaD23N in parenchymal and cerebrovascular amyloid depositsGenetics and molecular pathogenesis of sporadic and hereditary cerebral amyloid angiopathiesAmyloid-beta: a crucial factor in Alzheimer's disease.Microglia mediate the clearance of soluble Abeta through fluid phase macropinocytosis.Low-density lipoprotein receptor-related protein is decreased in optic neuropathy of Alzheimer diseaseAmyloid-β efflux from the central nervous system into the plasma.Reduced CSF Water Influx in Alzheimer's Disease Supporting the β-Amyloid Clearance Hypothesis.Sequential Amyloid-β Degradation by the Matrix Metalloproteases MMP-2 and MMP-9.Extracting β-amyloid from Alzheimer's disease.Nucleotides released from Aβ₁₋₄₂ -treated microglial cells increase cell migration and Aβ₁₋₄₂ uptake through P2Y₂ receptor activationAn N-terminal antibody promotes the transformation of amyloid fibrils into oligomers and enhances the neurotoxicity of amyloid-beta: the dust-raising effect.Physiological amyloid-beta clearance in the periphery and its therapeutic potential for Alzheimer's diseaseProtective effects of components of the Chinese herb grassleaf sweetflag rhizome on PC12 cells incubated with amyloid-beta42.Oleocanthal enhances amyloid-β clearance from the brains of TgSwDI mice and in vitro across a human blood-brain barrier modelAmyloid burden and sleep blood pressure in amnestic mild cognitive impairment.Extra-virgin olive oil attenuates amyloid-β and tau pathologies in the brains of TgSwDI mice.Role of ABC transporters in the pathogenesis of Alzheimer's diseaseIncreased levels of antigen-bound β-amyloid autoantibodies in serum and cerebrospinal fluid of Alzheimer's disease patients.Plasma Clusterin and the CLU Gene rs11136000 Variant Are Associated with Mild Cognitive Impairment in Type 2 Diabetic Patients.Raft aggregation with specific receptor recruitment is required for microglial phagocytosis of Abeta42.Fibrosis of the Choroid Plexus Filtration Membrane.In vivo Differential Brain Clearance and Catabolism of Monomeric and Oligomeric Alzheimer's Aβ proteinCerebral amyloid angiopathy: a systematic reviewThe role of clusterin in Alzheimer's disease: pathways, pathogenesis, and therapy.The potential mechanisms of Aβ-receptor for advanced glycation end-products interaction disrupting tight junctions of the blood-brain barrier in Alzheimer's disease.CD33 in Alzheimer's disease.Anti-amyloid Aggregation Activity of Natural Compounds: Implications for Alzheimer's Drug Discovery.Reduced beta-amyloid sensitivity for platelet-monocyte aggregates in EDTA blood of alzheimer patients.Development of a dual nanocarrier system as a potential stratagem against amyloid-induced toxicity.Effects of edaravone on amyloid-β precursor protein processing in SY5Y-APP695 cells.The p75NTR extracellular domain: a potential molecule regulating the solubility and removal of amyloid-β.Associations Between Hepatic Functions and Plasma Amyloid-Beta Levels-Implications for the Capacity of Liver in Peripheral Amyloid-Beta Clearance.Treatment with D3 removes amyloid deposits, reduces inflammation, and improves cognition in aged AβPP/PS1 double transgenic mice.Protein kinase C-regulated aβ production and clearance.
P2860
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P2860
Clearance of amyloid-beta in Alzheimer's disease: progress, problems and perspectives.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Clearance of amyloid-beta in Alzheimer's disease: progress, problems and perspectives.
@ast
Clearance of amyloid-beta in Alzheimer's disease: progress, problems and perspectives.
@en
type
label
Clearance of amyloid-beta in Alzheimer's disease: progress, problems and perspectives.
@ast
Clearance of amyloid-beta in Alzheimer's disease: progress, problems and perspectives.
@en
prefLabel
Clearance of amyloid-beta in Alzheimer's disease: progress, problems and perspectives.
@ast
Clearance of amyloid-beta in Alzheimer's disease: progress, problems and perspectives.
@en
P1433
P1476
Clearance of amyloid-beta in Alzheimer's disease: progress, problems and perspectives.
@en
P2093
Hua-Dong Zhou
P304
P356
10.1016/J.DRUDIS.2006.08.004
P577
2006-09-07T00:00:00Z