about
Modern antiepileptic drug development has failed to deliver: ways out of the current dilemma.In vivo pharmacology of BIIR 561 CL, a novel combined antagonist of AMPA receptors and voltage-dependent Na(+) channelsStem cells and modeling of autism spectrum disorders.Lateralization of temporal lobe epilepsy (TLE) and discrimination of TLE from extra-TLE using pattern analysis of magnetic resonance spectroscopic and volumetric data.Posttraumatic seizures in children with severe traumatic brain injury.Experimental and clinical evidence for loss of effect (tolerance) during prolonged treatment with antiepileptic drugs.Asymmetric accumulation of hippocampal 7S SNARE complexes occurs regardless of kindling paradigm.Temporal sequence of ictal discharges propagation in the corticolimbic basal ganglia system during amygdala kindled seizures in freely moving rats.The Spatiotemporal Dynamics of Phase Synchronization during Epileptogenesis in Amygdala-Kindling Mice.Low-frequency stimulation of the external globus palladium produces anti-epileptogenic and anti-ictogenic actions in rats.Defective function of GABA-containing synaptic vesicles in mice lacking the AP-3B clathrin adaptor.Benefits and risks of intranigral transplantation of GABA-producing cells subsequent to the establishment of kindling-induced seizures.Levetiracetam prevents kindling-induced asymmetric accumulation of hippocampal 7S SNARE complexes.Animal Models of Seizures and Epilepsy: Past, Present, and Future Role for the Discovery of Antiseizure Drugs.Chemogenetic silencing of the midline and intralaminar thalamus blocks amygdala-kindled seizures.Febrile convulsions induced by the combination of lipopolysaccharide and low-dose kainic acid enhance seizure susceptibility, not epileptogenesis, in rats.Self-reported illness from chemical odors in young adults without clinical syndromes or occupational exposures.The molecular basis of kindling.Comparing the anticonvulsant effects of low frequency stimulation of different brain sites on the amygdala kindling acquisition in rats.Modulation of c-Fos and BDNF protein expression in pentylenetetrazole-kindled mice following the treatment with novel antiepileptic compound HHL-6.Kindling increases the sensitivity of rats to adverse effects of certain antiepileptic drugs.Low Frequency Electrical Stimulation Either Prior to Or after Rapid Kindling Stimulation Inhibits the Kindling-Induced Epileptogenesis.Low-frequency stimulation inhibits epileptogenesis by modulating the early network of the limbic system as evaluated in amygdala kindling model.Accumulation of 7S SNARE complexes in hippocampal synaptosomes from chronically kindled rats.Unidirectional cross-tolerance from levetiracetam to carbamazepine in amygdala-kindled seizures.Neurobehavioral impairment and seizures from formaldehyde.Differential GABA(A) subunit expression following status epilepticus in seizure-prone and seizure-resistant rats: a putative mechanism for refractory drug response.Effects of Nefiracetam, a novel pyrrolidone-type nootropic agent, on the amygdala-kindled seizures in rats.Amygdaloid kindling elicits persistent changes in pertussis toxin-catalyzed ADP-ribosylation.The Pro-inflammatory Cytokine Interleukin-1β is a Key Regulatory Factor for the Postictal Suppression in Mice.Tetrodotoxin prevents posttraumatic epileptogenesis in rats.EEG sensitization during chemical exposure in women with and without chemical sensitivity of unknown etiology.Induced down-regulation of neuropeptide Y-Y1 receptors delays initiation of kindling.Histamine H1 receptor binding capacities in the amygdalas of the amygdaloid kindled rat.Selection of phenytoin responders and nonresponders in male and female amygdala-kindled Sprague-Dawley rats.Amygdala adenosine A1 receptors have no anticonvulsant effect on piriform cortex-kindled seizures in rat.Amygdala-kindling induces a lasting reduction of GABA-immunoreactive neurons in a discrete area of the ipsilateral piriform cortex.Seizure patterns of Mongolian gerbils subjected to a prolonged weekly test schedule: evidence for a kindling-like phenomenon in the adult population.Antiepileptic effects of tiagabine, a selective GABA uptake inhibitor, in the rat kindling model of temporal lobe epilepsy.The Search for New Screening Models of Pharmacoresistant Epilepsy: Is Induction of Acute Seizures in Epileptic Rodents a Suitable Approach?
P2860
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P2860
description
1990 nî lūn-bûn
@nan
1990年の論文
@ja
1990年論文
@yue
1990年論文
@zh-hant
1990年論文
@zh-hk
1990年論文
@zh-mo
1990年論文
@zh-tw
1990年论文
@wuu
1990年论文
@zh
1990年论文
@zh-cn
name
Kindling: basic mechanisms and clinical validity.
@ast
Kindling: basic mechanisms and clinical validity.
@en
type
label
Kindling: basic mechanisms and clinical validity.
@ast
Kindling: basic mechanisms and clinical validity.
@en
prefLabel
Kindling: basic mechanisms and clinical validity.
@ast
Kindling: basic mechanisms and clinical validity.
@en
P2093
P1476
Kindling: basic mechanisms and clinical validity.
@en
P2093
P304
P356
10.1016/0013-4694(90)90099-6
P577
1990-11-01T00:00:00Z