Metformin selectively affects human glioblastoma tumor-initiating cell viability: A role for metformin-induced inhibition of Akt. - Wikidata - wikimedia - TriplyDB

Metformin selectively affects human glioblastoma tumor-initiating cell viability: A role for metformin-induced inhibition of Akt.

Metformin selectively affects human glioblastoma tumor-initiating cell viability: A role for metformin-induced inhibition of Akt.

http://www.wikidata.org/entity/Q36604614

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PPAR Gamma in Neuroblastoma: The Translational Perspectives of Hypoglycemic Drugs Diabetes, use of antidiabetic drugs, and the risk of glioma Low concentrations of metformin selectively inhibit CD133⁺ cell proliferation in pancreatic cancer and have anticancer action Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma Cancer stem cells: a systems biology view of their role in prognosis and therapy Synthesis and anti-breast cancer evaluation of novel N-(guanidinyl)benzenesulfonamides Opioid receptor activation triggering downregulation of cAMP improves effectiveness of anti-cancer drugs in treatment of glioblastoma Metformin reduces thyroid cancer risk in Taiwanese patients with type 2 diabetes.microRNAs and cancer metabolism reprogramming: the paradigm of metformin Berberine suppresses gero-conversion from cell cycle arrest to senescence.Effects of metformin on retinoblastoma growth in vitro and in vivo.Chemical inhibition of acetyl-CoA carboxylase suppresses self-renewal growth of cancer stem cells.Metformin impairs Rho GTPase signaling to induce apoptosis in neuroblastoma cells and inhibits growth of tumors in the xenograft mouse model of neuroblastoma.Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current Effects of metformin on CD133+ colorectal cancer cells in diabetic patients In vitro and in vivo antiproliferative activity of metformin on stem-like cells isolated from spontaneous canine mammary carcinomas: translational implications for human tumors Metformin inhibits growth of human glioblastoma cells and enhances therapeutic response Fasting induces anti-Warburg effect that increases respiration but reduces ATP-synthesis to promote apoptosis in colon cancer models.Studying Pancreatic Cancer Stem Cell Characteristics for Developing New Treatment Strategies Metformin Increases Sensitivity of Pancreatic Cancer Cells to Gemcitabine by Reducing CD133+ Cell Populations and Suppressing ERK/P70S6K Signaling.Paeoniflorin inhibits human glioma cells via STAT3 degradation by the ubiquitin-proteasome pathway.Metformin and Ara-a Effectively Suppress Brain Cancer by Targeting Cancer Stem/Progenitor Cells.Metformin and temozolomide act synergistically to inhibit growth of glioma cells and glioma stem cells in vitro and in vivo.5-fluorouracil resistant colon cancer cells are addicted to OXPHOS to survive and enhance stem-like traits.Sorafenib selectively depletes human glioblastoma tumor-initiating cells from primary cultures.Tristetraprolin mediates the anti-proliferative effects of metformin in breast cancer cells Temozolomide in combination with metformin act synergistically to inhibit proliferation and expansion of glioma stem-like cells.Bulk pancreatic cancer cells can convert into cancer stem cells(CSCs) in vitro and 2 compounds can target these CSCs Metformin inhibits proliferation and migration of glioblastoma cells independently of TGF-β2.Metformin Enhances the Therapy Effects of Anti-IGF-1R mAb Figitumumab to NSCLC.Inhibition of the Autophagy Pathway Synergistically Potentiates the Cytotoxic Activity of Givinostat (ITF2357) on Human Glioblastoma Cancer Stem Cells.Cellular prion protein controls stem cell-like properties of human glioblastoma tumor-initiating cells Direct inhibition of hexokinase activity by metformin at least partially impairs glucose metabolism and tumor growth in experimental breast cancer.Metformin: On Ongoing Journey across Diabetes, Cancer Therapy and Prevention.Altered gene products involved in the malignant reprogramming of cancer stem/progenitor cells and multitargeted therapies.Dynamic Interactions Between Cancer Stem Cells And Their Stromal Partners.Obesity and melanoma: exploring molecular links.Repositioning metformin in cancer: genetics, drug targets, and new ways of delivery.New molecules and old drugs as emerging approaches to selectively target human glioblastoma cancer stem cells.Glioma stem cells: markers, hallmarks and therapeutic targeting by metformin.

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Metformin selectively affects human glioblastoma tumor-initiating cell viability: A role for metformin-induced inhibition of Akt.

http://www.wikidata.org/entity/Q36604614

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Adirano Bajetto

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Alessandra Pattarozzi

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Alessia Parodi

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Gianluigi Zona

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Systematic Review: Comparative Effectiveness and Safety of Oral Medications for Type 2 Diabetes Mellitus

Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement

Identification of a cancer stem cell in human brain tumors

Identification of selective inhibitors of cancer stem cells by high-throughput screening

Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

Analysis of gene expression and chemoresistance of CD133+ cancer stem cells in glioblastoma

Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

Metformin and reduced risk of cancer in diabetic patients

Monitoring of bone marrow cell homing into the infarcted human myocardium.

Metformin activates an atypical PKC-CBP pathway to promote neurogenesis and enhance spatial memory formation.

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Federica Barbieri

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Gianmario Sambuceti

Michela Massollo

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