A TALEN genome-editing system for generating human stem cell-based disease models. - Wikidata - wikimedia - TriplyDB

A TALEN genome-editing system for generating human stem cell-based disease models.

A TALEN genome-editing system for generating human stem cell-based disease models.

http://www.wikidata.org/entity/Q36604889

about

Genome engineering using the CRISPR-Cas9 system A Broad Overview and Review of CRISPR-Cas Technology and Stem Cells Site-Specific Genome Engineering in Human Pluripotent Stem Cells Human induced pluripotent stem cells for monogenic disease modelling and therapy Genome Engineering with TALE and CRISPR Systems in Neuroscience Genome-editing Technologies for Gene and Cell Therapy Hematopoietic stem cell expansion and generation: the ways to make a breakthrough Genome Editing and Its Applications in Model Organisms Origins of Programmable Nucleases for Genome Engineering Oligonucleotide-directed mutagenesis for precision gene editing Single-Base Pair Genome Editing in Human Cells by Using Site-Specific Endonucleases Understanding the molecular basis of autism in a dish using hiPSCs-derived neurons from ASD patients Dissecting diabetes/metabolic disease mechanisms using pluripotent stem cells and genome editing tools Modeling Viral Infectious Diseases and Development of Antiviral Therapies Using Human Induced Pluripotent Stem Cell-Derived Systems Reprogramming and transdifferentiation for cardiovascular development and regenerative medicine: where do we stand?Cutting-edge microfabricated biomedical tools for human pluripotent stem cell research Transcription activator-like effectors: a toolkit for synthetic biology Disease modeling and cell based therapy with iPSC: future therapeutic option with fast and safe application Mechanisms and models of endoplasmic reticulum stress in chondrodysplasia New opportunities: harnessing induced pluripotency for discovery in diabetes and metabolism Progress and prospects of engineered sequence-specific DNA modulating technologies for the management of liver diseases Quantifying on- and off-target genome editing Low-Dose Irradiation Enhances Gene Targeting in Human Pluripotent Stem Cells Transcription activator-like effector nuclease (TALEN)-mediated CLYBL targeting enables enhanced transgene expression and one-step generation of dual reporter human induced pluripotent stem cell (iPSC) and neural stem cell (NSC) lines.Bioluminescent imaging of genetically selected induced pluripotent stem cell-derived cardiomyocytes after transplantation into infarcted heart of syngeneic recipients Genome editing: the road of CRISPR/Cas9 from bench to clinic Generation of functional human pancreatic β cells in vitro The position of DNA cleavage by TALENs and cell synchronization influences the frequency of gene editing directed by single-stranded oligonucleotides Simple and efficient methods for enrichment and isolation of endonuclease modified cells Precise gene modification mediated by TALEN and single-stranded oligodeoxynucleotides in human cells Targeted manipulation of the sortilin-progranulin axis rescues progranulin haploinsufficiency Resources for functional genomics studies in Drosophila melanogaster ZFN, TALEN, and CRISPR/Cas-based methods for genome engineering Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity An episomal vector-based CRISPR/Cas9 system for highly efficient gene knockout in human pluripotent stem cells Future translational applications from the contemporary genomics era: a scientific statement from the American Heart Association Genome editing of isogenic human induced pluripotent stem cells recapitulates long QT phenotype for drug testing Broad specificity profiling of TALENs results in engineered nucleases with improved DNA-cleavage specificity Assembly and validation of versatile transcription activator-like effector libraries Systematic screening of isogenic cancer cells identifies DUSP6 as context-specific synthetic lethal target in melanoma.

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A TALEN genome-editing system for generating human stem cell-based disease models.

http://www.wikidata.org/entity/Q36604889

description

2012 nî lūn-bûn

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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name

A TALEN genome-editing system for generating human stem cell-based disease models.

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A TALEN genome-editing system for generating human stem cell-based disease models.

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type

label

A TALEN genome-editing system for generating human stem cell-based disease models.

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A TALEN genome-editing system for generating human stem cell-based disease models.

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prefLabel

A TALEN genome-editing system for generating human stem cell-based disease models.

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A TALEN genome-editing system for generating human stem cell-based disease models.

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J.STEM.2012.11.011

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P1476

A TALEN genome-editing system for generating human stem cell-based disease models.

@en

P2093

Adrian Veres

http://www.w3.org/2001/XMLSchema#string

Alexander Tang

http://www.w3.org/2001/XMLSchema#string

Amy Wann

http://www.w3.org/2001/XMLSchema#string

Annie Moisan

http://www.w3.org/2001/XMLSchema#string

Chad A Cowan

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Daniel L Motola

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Derek T Peters

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Emmanuel Figueroa

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Eric Banks

http://www.w3.org/2001/XMLSchema#string

Esperance A K Schaefer

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P2860

Sortilin is essential and sufficient for the formation of Glut4 storage vesicles in 3T3-L1 adipocytes

TAL nucleases (TALNs): hybrid proteins composed of TAL effectors and FokI DNA-cleavage domain

Targeting DNA double-strand breaks with TAL effector nucleases

Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

Severe diabetes, age-dependent loss of adipose tissue, and mild growth deficiency in mice lacking Akt2/PKB beta

Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins

Apolipoprotein E but Not B Is Required for the Formation of Infectious Hepatitis C Virus Particles

Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA.

Sortilin: a receptor to regulate neuronal viability and function

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238-251

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scholarly article

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10.1016/J.STEM.2012.11.011

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2

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12

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Raymond T Chung

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2012-12-13T00:00:00Z

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233940240

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23246482

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3570604

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