Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy - Wikidata - wikimedia - TriplyDB

Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy

Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy

http://www.wikidata.org/entity/Q36608029

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Profile of suvorexant in the management of insomnia Orexin Neurons Respond Differentially to Auditory Cues Associated with Appetitive versus Aversive Outcomes.GABAB agonism promotes sleep and reduces cataplexy in murine narcolepsy.Conditional ablation of orexin/hypocretin neurons: a new mouse model for the study of narcolepsy and orexin system function.Suvorexant for the treatment of insomnia.Homeostatic sleep pressure is the primary factor for activation of cortical nNOS/NK1 neurons Orexin Receptor Antagonism Improves Sleep and Reduces Seizures in Kcna1-null Mice.Effect of two GABA-ergic drugs on the cognitive functions of rapid eye movement in sleep-deprived and recovered rats A role for cortical nNOS/NK1 neurons in coupling homeostatic sleep drive to EEG slow wave activity.Orexin-1 receptor blockade dysregulates REM sleep in the presence of orexin-2 receptor antagonism.Insights into the pharmacological targeting of the trigeminocervical complex in the context of treatments of migraine.Challenges in the development of therapeutics for narcolepsy.Orexin OX2 Receptor Antagonists as Sleep Aids.Locus Coeruleus and Tuberomammillary Nuclei Ablations Attenuate Hypocretin/Orexin Antagonist-Mediated REM Sleep.Kinetic properties of "dual" orexin receptor antagonists at OX1R and OX2R orexin receptors.Distinct effects of IPSU and suvorexant on mouse sleep architecture.Trace Amine-Associated Receptor 1 Agonists as Narcolepsy Therapeutics.The AWAKEN survey: knowledge of narcolepsy among physicians and the general population.Physiology. The perfect hypnotic?Parallel Arousal Pathways in the Lateral Hypothalamus Orexin Receptor Antagonists

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Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy

http://www.wikidata.org/entity/Q36608029

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2013 nî lūn-bûn

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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2013年论文

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2013年论文

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name

Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy

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Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy

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Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy

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Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy

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Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy

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Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy

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Almorexant promotes sleep and exacerbates cataplexy in a murine model of narcolepsy

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Deepti R Warrier

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Sarah Wurts Black

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Simon P Fisher

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Stephen R Morairty

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Tsui-Ming Chen

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P2860

Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle

Dual hypocretin receptor antagonism is more effective for sleep promotion than antagonism of either receptor alone

Cholinergic modulation of narcoleptic attacks in double orexin receptor knockout mice

The sleep disorder canine narcolepsy is caused by a mutation in the hypocretin (orexin) receptor 2 gene

A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains

Narcolepsy in orexin knockout mice: molecular genetics of sleep regulation

Feeding-elicited cataplexy in orexin knockout mice.

Orexin peptides prevent cataplexy and improve wakefulness in an orexin neuron-ablated model of narcolepsy in mice.

Reduced number of hypocretin neurons in human narcolepsy.

Hypocretin and its emerging role as a target for treatment of sleep disorders.

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325-336

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10.5665/SLEEP.2442

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3

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36

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Thomas S. Kilduff

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2013-03-01T00:00:00Z

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235756431

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