The Wnt pathway regulator DKK1 is preferentially expressed in hormone-resistant breast tumours and in some common cancer types. - Wikidata - wikimedia - TriplyDB

The Wnt pathway regulator DKK1 is preferentially expressed in hormone-resistant breast tumours and in some common cancer types.

The Wnt pathway regulator DKK1 is preferentially expressed in hormone-resistant breast tumours and in some common cancer types.

http://www.wikidata.org/entity/Q36609873

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Mammary Development and Breast Cancer: A Wnt Perspective Potential prognostic, diagnostic and therapeutic markers for human gastric cancer Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer Role of the Wnt/β-catenin pathway in gastric cancer: An in-depth literature review Nuclear PTEN levels and G2 progression in melanoma cells Negative regulation of bone formation by the transmembrane Wnt antagonist Kremen-2.Decreased Circulating Levels of Dickkopf-1 in Patients with Exudative Age-related Macular Degeneration CBX7 negatively regulates migration and invasion in glioma via Wnt/β-catenin pathway inactivation Dickkopf1 regulates fate decision and drives breast cancer stem cells to differentiation: an experimentally supported mathematical model Epigenetic regulation of microRNA genes and the role of miR-34b in cell invasion and motility in human melanoma Elevated levels of Dickkopf-1 are associated with β-catenin accumulation and poor prognosis in patients with chondrosarcoma.Expression of dickkopf-1 and beta-catenin related to the prognosis of breast cancer patients with triple negative phenotype.Sox2 promotes tamoxifen resistance in breast cancer cells.Key signaling nodes in mammary gland development and cancer: β-catenin.Serum Dickkopf-1 (DKK1) is significantly lower in patients with lung cancer but is rapidly normalized after treatment Dickkopf-1 is oncogenic and involved in invasive growth in non small cell lung cancer.Molecular changes in pre-metastatic lymph nodes of esophageal cancer patients.Global Developmental Gene Programing Involves a Nuclear Form of Fibroblast Growth Factor Receptor-1 (FGFR1).Dickkopf1: a tumor suppressor or metastasis promoter?Endocytic Adaptor Protein Tollip Inhibits Canonical Wnt Signaling.Dickkopf-1 expression increases early in prostate cancer development and decreases during progression from primary tumor to metastasis DKK1 is a potential novel mediator of cisplatin-refractoriness in non-small cell lung cancer cell lines The Wnt inhibitor dickkopf-1: a link between breast cancer and bone metastases.Dickkopf-1 expression is a novel prognostic marker for gastric cancer Redox-modulating agents target NOX2-dependent IKKε oncogenic kinase expression and proliferation in human breast cancer cell lines Serum Dickkopf-1 as a Biomarker for the Diagnosis of Hepatocellular Carcinoma.Prostate-derived Ets transcription factor overexpression is associated with nodal metastasis and hormone receptor positivity in invasive breast cancer Serum dickkopf-1 as a biomarker in screening gastrointestinal cancers: a systematic review and meta-analysis.High Dickkopf-1 expression is associated with poor prognosis in patients with advanced urothelial carcinoma.Serum dickkopf-1 is a novel serological biomarker for the diagnosis and prognosis of pancreatic cancer.Wnt signaling in bone development and disease: making stronger bone with Wnts Gene regulatory network inference: evaluation and application to ovarian cancer allows the prioritization of drug targets.The Wnt antagonist Dkk1 regulates intestinal epithelial homeostasis and wound repair.A potential role for Dkk-1 in the pathogenesis of osteosarcoma predicts novel diagnostic and treatment strategies Downregulation of MicroRNA-152 contributes to high expression of DKK1 in multiple myeloma miR-493 mediated DKK1 down-regulation confers proliferation, invasion and chemo-resistance in gastric cancer cells.DNAJB6 governs a novel regulatory loop determining Wnt/β-catenin signalling activity.Understanding signaling cascades in melanoma Wnt and Wnt inhibitors in bone metastasis.The role of Dickkopf-1 in bone development, homeostasis, and disease

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P2860

The Wnt pathway regulator DKK1 is preferentially expressed in hormone-resistant breast tumours and in some common cancer types.

http://www.wikidata.org/entity/Q36609873

description

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British Journal of Cancer

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P2860

Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling

Head inducer Dickkopf-1 is a ligand for Wnt coreceptor LRP6

Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling

Dickkopf1 is required for embryonic head induction and limb morphogenesis in the mouse

The role of the Wnt-signaling antagonist DKK1 in the development of osteolytic lesions in multiple myeloma

Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer

Inhibition of Wnt activity induces heart formation from posterior mesoderm

Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

Quantitative in situ analysis of beta-catenin expression in breast cancer shows decreased expression is associated with poor outcome.

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10.1038/SJ.BJC.6603579

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1026471157

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