Phentolamine block of KATP channels is mediated by Kir6.2.
about
Identification of the monomeric G-protein, Rhes, as an efaroxan-regulated protein in the pancreatic beta-cellRunning out of time: the decline of channel activity and nucleotide activation in adenosine triphosphate-sensitive K-channelsMechanism of cloned ATP-sensitive potassium channel activation by oleoyl-CoAMechanism of terfenadine block of ATP-sensitive K(+) channelsDual action of ZD6169, a novel K(+) channel opener, on ATP-sensitive K(+) channels in pig urethral myocytesCibenzoline, an ATP-sensitive K(+) channel blocker, binds to the K(+)-binding site from the cytoplasmic side of gastric H(+),K(+)-ATPaseThe effects of flecainide on ATP-sensitive K(+) channels in pig urethral myocytesAltered functional properties of KATP channel conferred by a novel splice variant of SUR1.Phentolamine inhibits exocytosis of glucagon by Gi2 protein-dependent activation of calcineurin in rat pancreatic alpha -cells.Pharmacological stimulation and inhibition of insulin secretion in mouse islets lacking ATP-sensitive K+ channelsImidazolines and pancreatic hormone secretion.Novel targets and techniques in imidazoline receptor research.Hyperinsulinism of infancy: towards an understanding of unregulated insulin release. European Network for Research into Hyperinsulinism in Infancy.Ions, genes and insulin release: from basic science to clinical disease. Based on the 1998 R. D. Lawrence Lecture.Mutations within the P-loop of Kir6.2 modulate the intraburst kinetics of the ATP-sensitive potassium channel.Physiological and pharmacological regulation of insulin release: insights offered through exploitation of insulin-secreting cell lines.Modeling regulation of cardiac KATP and L-type Ca2+ currents by ATP, ADP, and Mg2+Sensitivity of Kir6.2-SUR1 currents, in the absence and presence of sodium azide, to the K(ATP) channel inhibitors, ciclazindol and englitazoneThe antimalarial agent mefloquine inhibits ATP-sensitive K-channels.Inhibition of ATP-sensitive potassium channels by haloperidol.Protection by imidazol(ine) drugs and agmatine of glutamate-induced neurotoxicity in cultured cerebellar granule cells through blockade of NMDA receptor.Pharmacogenomics of cardiovascular complications in diabetes and obesity.Imidazoline receptors: new targets for antihyperglycaemic drugs.Molecular analysis of ATP-sensitive K channel gating and implications for channel inhibition by ATP.Review. SUR1: a unique ATP-binding cassette protein that functions as an ion channel regulator.Pharmacological properties of the central antihypertensive agent, moxonidine.Significance of the imidazoline receptors in toxicology.A new benzoxazine compound blocks KATP channels in pancreatic beta cells: molecular basis for tissue selectivity in vitro and hypoglycaemic action in vivo.Acute and long-term effects of nateglinide on insulin secretory pathways.Induced desensitization of the insulinotropic effects of antidiabetic drugs, BTS 67 582 and tolbutamide.In vitro mechanism of action on insulin release of S-22068, a new putative antidiabetic compound.Imidazolines and the pancreatic B-cell. Actions and binding sites.The sulphonylurea receptor SUR1 regulates ATP-sensitive mouse Kir6.2 K+ channels linked to the green fluorescent protein in human embryonic kidney cells (HEK 293).Multiple effector pathways regulate the insulin secretory response to the imidazoline RX871024 in isolated rat pancreatic islets.Expression of functionally active ATP-sensitive K-channels in insect cells using baculovirus.Novel I1-Imidazoline Agonist S43126 Augment Insulin Secretion in Min6 Cells.Functional and electrophysiological effects of a novel imidazoline-based K(ATP) channel blocker, IMID-4F.Affinity isolation of imidazoline binding proteins from rat brain using 5-amino-efaroxan as a ligand.Involvement of the n-terminus of Kir6.2 in coupling to the sulphonylurea receptor.Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP.
P2860
Q24295155-C434837A-1F97-43F3-9665-3852D9225AAEQ26744692-7F91E4D6-D806-4A18-A714-1CCBAE165A2DQ28284068-6A1BB879-39EB-4E64-9181-FF56E96A2E08Q28344540-A9166297-9A09-4542-9A1C-530EDAC66A51Q28363846-F1D41EA4-BD28-447F-9A3A-6A161C40A082Q28366036-EB020B5C-2DC6-4041-9C5B-46BB56B93AAFQ28367900-E67D40ED-197F-432B-8C1E-81D8E5D440A5Q30821155-F82BB980-FC8A-47D7-87A2-AF9F64C76922Q31440408-29C16B7C-D3E0-42AB-8F0E-FD756146E04FQ33685956-87D2B28A-12C1-4D5D-BF7F-9DE0F8ABDC5CQ33693050-11C74C60-5304-4F86-912B-32E6F951DFDCQ33693060-22EE63AC-9655-473F-9068-4C2CC6CBDAFFQ33844331-598ADCC6-C72C-4AEB-B925-2FFE5B2CFA08Q33880824-3B86A420-A715-4A8F-9DA8-4C35962F3688Q34093658-24D2FE9E-85C0-4FC7-8DFC-41CB84101248Q34163136-513A478A-432C-4983-881E-51ABEC5D684AQ34189484-896F616B-95EF-45B6-ACD4-4FF79096A42EQ35042370-FCA87DF1-578E-4539-96E3-335ECB6A03B1Q35042825-3F2148DF-2D9D-49DB-BE67-43DCB7F6D0DFQ35048471-BF9229EA-60FF-459B-B119-39099EE69AECQ35566498-68039D2A-23B1-4535-BEC7-5B1FC10AF135Q35647167-3CDE2205-FF8F-4CB0-ACD8-B059832373FEQ36181333-6DCFF563-3B47-41C0-BA6E-DBEB0A95EF9BQ36436065-45790F29-FDB8-41CF-AC4D-18E42E9D7C11Q37319861-ECABA359-5A94-4883-88FF-81268DC53582Q37925014-C2AC1CB6-0A16-40D8-8F5E-8AE5D4FEF246Q38199190-B1F621DA-6C7B-4B14-A481-6A94593294AEQ40216800-35FFCE89-6274-41C7-ADE4-21C2C47F6BEFQ40553689-B1D917CA-CA15-444A-BF33-902E69E2EA28Q40880365-4097AA22-69BE-49C3-8028-1454A2765C48Q40918880-182FC8A9-FD80-482F-AD10-960564C0B477Q40940376-DE39200A-7CB0-442C-8F6B-DB7D41AE1D3EQ41015961-315B2FA5-C2E6-4563-8E08-1D0AE96F367EQ41859848-0FABE586-F7C0-46E7-988B-8518C9BAB297Q42060324-0AC62281-6B5A-49A5-B292-0D9D89059CBDQ42071939-D00DFBB3-0D8D-41C9-AA42-1FE844486938Q43261611-3B4A07A4-EF28-432B-9D21-286F99BFBBB0Q48226871-6093C158-02CF-48D1-811F-F1F6C143A807Q48914424-B1410BB8-9815-40E6-976F-A527036FE00AQ50741434-AF7E7B0E-F78D-4F46-9D7F-D7B4B5E3F0C7
P2860
Phentolamine block of KATP channels is mediated by Kir6.2.
description
1997 nî lūn-bûn
@nan
1997年の論文
@ja
1997年論文
@yue
1997年論文
@zh-hant
1997年論文
@zh-hk
1997年論文
@zh-mo
1997年論文
@zh-tw
1997年论文
@wuu
1997年论文
@zh
1997年论文
@zh-cn
name
Phentolamine block of KATP channels is mediated by Kir6.2.
@ast
Phentolamine block of KATP channels is mediated by Kir6.2.
@en
type
label
Phentolamine block of KATP channels is mediated by Kir6.2.
@ast
Phentolamine block of KATP channels is mediated by Kir6.2.
@en
prefLabel
Phentolamine block of KATP channels is mediated by Kir6.2.
@ast
Phentolamine block of KATP channels is mediated by Kir6.2.
@en
P2860
P356
P1476
Phentolamine block of KATP channels is mediated by Kir6.2.
@en
P2093
P2860
P304
11716-11720
P356
10.1073/PNAS.94.21.11716
P407
P577
1997-10-01T00:00:00Z