Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP.
about
Molecular mechanism for ATP-dependent closure of the K+ channel Kir6.2Phorbol ester impairs electrical excitation of rat pancreatic beta-cells through PKC-independent activation of KATP channelsMapping of the physical interaction between the intracellular domains of an inwardly rectifying potassium channel, Kir6.2Novel nucleotide-binding sites in ATP-sensitive potassium channels formed at gating interfaces.Identification and characterization of a novel member of the ATP-sensitive K+ channel subunit family, Kir6.3, in zebrafish.The I182 region of k(ir)6.2 is closely associated with ligand binding in K(ATP) channel inhibition by ATPConcerted gating mechanism underlying KATP channel inhibition by ATP.Direct interaction of Na-azide with the KATP channel.ATP-dependent interaction of the cytosolic domains of the inwardly rectifying K+ channel Kir6.2 revealed by fluorescence resonance energy transferGating mechanism of KATP channels: function fits form.The role of NH2-terminal positive charges in the activity of inward rectifier KATP channelsDecomposition of slide helix contributions to ATP-dependent inhibition of Kir6.2 channelsCurrent understanding of K ATP channels in neonatal diseases: focus on insulin secretion disorders.Identification of residues contributing to the ATP binding site of Kir6.2.A short motif in Kir6.1 consisting of four phosphorylation repeats underlies the vascular KATP channel inhibition by protein kinase C.ATP sensitivity of ATP-sensitive K+ channels: role of the gamma phosphate group of ATP and the R50 residue of mouse Kir6.2.Molecular determinants of cardiac K(ATP) channel activation by epoxyeicosatrienoic acids.Allosteric modulation of the mouse Kir6.2 channel by intracellular H+ and ATP.Functional analysis of a structural model of the ATP-binding site of the KATP channel Kir6.2 subunit.Anti-diabetic drug binding site in a mammalian KATP channel revealed by Cryo-EM.On the mechanism of ADP-induced alteration of sulphonylurea sensitivity in cardiac ATP-sensitive K(+) channels.The role of lysine 185 in the kir6.2 subunit of the ATP-sensitive channel in channel inhibition by ATP.Involvement of the n-terminus of Kir6.2 in coupling to the sulphonylurea receptor.KCNJ11 activating mutations in Italian patients with permanent neonatal diabetes.Cryo-electron microscopy structures and progress toward a dynamic understanding of KATP channels.Ligand binding and conformational changes of SUR1 subunit in pancreatic ATP-sensitive potassium channels.Functional Analysis of a Mutant Sulfonylurea Receptor, SUR1-R1420C, That Is Responsible for Persistent Hyperinsulinemic Hypoglycemia of Infancy
P2860
Q24308180-9B9354C2-069A-443C-80FC-953C8DD4F9ECQ24804261-C4184C80-22B4-4BA6-9D30-95BDB51C0B49Q28137825-7F28708B-B1AB-4901-B665-E9963320E2ADQ28564824-0803D467-75D4-4AD5-A366-6206C1976C4DQ33228145-C4B7F3DA-57FD-4421-A800-CEF2D82FF9F3Q34173659-BF017377-62CF-49D5-82B6-EBAF4EC16D8EQ34185246-7D7174DD-93A3-4AC2-AF5D-81E2097E243EQ35042895-4A57161D-2E8D-4B91-AC7A-7BF26A2ADD74Q35121325-E04883A7-1163-46FC-97D4-72D312FEE537Q35569293-2058DDA6-F73A-4E9F-B19E-78D541EA5334Q36436454-03EA1B14-4EBB-4943-A232-98D5513A0B56Q37095382-204CEBF4-15AD-496B-A872-B39E2A15BF71Q37878248-172F5F92-CCC4-400E-B1A5-3DB9668B84EFQ39777428-24301C91-1BE4-44A2-9C37-AC0B07D1EEAFQ40042590-C5650016-A679-4CF7-9B68-F91B78DC4AFCQ40372990-5A1C860F-7FEA-4971-9457-3ED49960595AQ40448045-C3F3E260-33EC-4500-B2A3-838E8DDF73DAQ40707353-E6FF586B-68A1-4A90-988E-8CEEC879000CQ40949543-4F06ABE3-3AB5-4323-B446-14770D234F2AQ42637813-49A31C47-61DE-499A-AAE9-E90082164A11Q43264653-4D5C4A79-F9ED-41C9-A1F3-5E14501E9484Q48906684-BDA6F6B9-3851-40EC-AFBD-9DB2CF797C0CQ48914424-DD52C3C1-A02C-4BCD-95A0-0710E1A8DF07Q52085176-D8D4E8C3-31A3-4347-9B11-1DCBC22C8320Q52312167-1B8D6B1D-0CCA-4919-B888-29FB44E62838Q55283497-019146BA-8C4C-40DF-9039-2549B4FFE272Q58449724-E6A0716B-5379-4D3F-922B-3DC7DA57AC82
P2860
Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP.
description
1999 nî lūn-bûn
@nan
1999年の論文
@ja
1999年学术文章
@wuu
1999年学术文章
@zh
1999年学术文章
@zh-cn
1999年学术文章
@zh-hans
1999年学术文章
@zh-my
1999年学术文章
@zh-sg
1999年學術文章
@yue
1999年學術文章
@zh-hant
name
Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP.
@en
Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP.
@nl
type
label
Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP.
@en
Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP.
@nl
prefLabel
Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP.
@en
Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP.
@nl
P2093
P2860
P1476
Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP
@en
P2093
P2860
P356
10.1111/J.1469-7793.1999.019AF.X
P407
P478
514 ( Pt 1)
P577
1999-01-01T00:00:00Z