Pharmacogenomic and structural analysis of constitutive g protein-coupled receptor activity.
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Characterization of an orphan G protein-coupled receptor, GPR20, that constitutively activates Gi proteinsThe role of opiorphins (endogenous neutral endopeptidase inhibitors) in urogenital smooth muscle biologyInternational Union of Basic and Clinical Pharmacology. XCVIII. Histamine ReceptorsG-protein-coupled receptors targeting: the allosteric approachHigh-resolution crystal structure of human protease-activated receptor 1Stabilized G protein binding site in the structure of constitutively active metarhodopsin-IIUnderstanding functional residues of the cannabinoid CB1.Structural role of the T94I rhodopsin mutation in congenital stationary night blindnessChemogenomic analysis of G-protein coupled receptors and their ligands deciphers locks and keys governing diverse aspects of signallingActivation of G protein-coupled receptors: beyond two-state models and tertiary conformational changes.Activation of GABA(B) receptors inhibits protein kinase B/glycogen synthase kinase 3 signaling.SEB-3, a CRF receptor-like GPCR, regulates locomotor activity states, stress responses and ethanol tolerance in Caenorhabditis elegansThe Fog signaling pathway: insights into signaling in morphogenesis.Structural heterogeneity of the μ-opioid receptor's conformational ensemble in the apo statePrinciples and determinants of G-protein coupling by the rhodopsin-like thyrotropin receptor.Regulation of GPR54 signaling by GRK2 and {beta}-arrestinThe emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer.Structural and dynamic effects of cholesterol at preferred sites of interaction with rhodopsin identified from microsecond length molecular dynamics simulations.Molecular basis of ligand dissociation in β-adrenergic receptorsA knockout mutation of a constitutive GPCR in Tetrahymena decreases both G-protein activity and chemoattraction.Allosteric modulation of β-arrestin-biased angiotensin II type 1 receptor signaling by membrane stretch.The role of Cysteine 6.47 in class A GPCRsRemote control of neuronal signaling.Modulation of cellular signaling by herpesvirus-encoded G protein-coupled receptors.Quantifying conformational changes in GPCRs: glimpse of a common functional mechanism.Ensemble of G protein-coupled receptor active states.Constitutive formation of an RXFP1-signalosome: a novel paradigm in GPCR function and regulation.Insights into Basal Signaling Regulation, Oligomerization, and Structural Organization of the Human G-Protein Coupled Receptor 83.Identification and characterization of distinct C-terminal domains of the human hydroxycarboxylic acid receptor-2 that are essential for receptor export, constitutive activity, desensitization, and internalization.Desensitization of herpesvirus-encoded G protein-coupled receptors.Structure, function and physiological consequences of virally encoded chemokine seven transmembrane receptorsConstitutive somatostatin receptor subtype 2 activity attenuates GH synthesis.Stimulation of proglucagon gene expression by human GPR119 in enteroendocrine L-cell line GLUTag.Evolutionary survey of druggable protein targets with respect to their subcellular localizations.Agonist binding, agonist affinity and agonist efficacy at G protein-coupled receptorsLigands raise the constraint that limits constitutive activation in G protein-coupled opioid receptors.Novel insights on thyroid-stimulating hormone receptor signal transduction.Constitutive somatostatin receptor activity determines tonic pituitary cell response.The end of a myth: cloning and characterization of the ovine melatonin MT(2) receptor.Structure and dynamics of a constitutively active neurotensin receptor.
P2860
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P2860
Pharmacogenomic and structural analysis of constitutive g protein-coupled receptor activity.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Pharmacogenomic and structural ...... ein-coupled receptor activity.
@ast
Pharmacogenomic and structural ...... ein-coupled receptor activity.
@en
type
label
Pharmacogenomic and structural ...... ein-coupled receptor activity.
@ast
Pharmacogenomic and structural ...... ein-coupled receptor activity.
@en
prefLabel
Pharmacogenomic and structural ...... ein-coupled receptor activity.
@ast
Pharmacogenomic and structural ...... ein-coupled receptor activity.
@en
P2093
P1476
Pharmacogenomic and structural ...... tein-coupled receptor activity
@en
P2093
Aldo Jongejan
Henk Timmerman
Henry F Vischer
Martine J Smit
Remko A Bakker
P356
10.1146/ANNUREV.PHARMTOX.47.120505.105126
P577
2007-01-01T00:00:00Z