The nonstructural glycoprotein of rotavirus affects intracellular calcium levels
about
Pathogenesis of intestinal and systemic rotavirus infectionRotaviruses: from pathogenesis to vaccinationRotavirus vaccines and pathogenesis: 2008The rotavirus enterotoxin NSP4 mobilizes intracellular calcium in human intestinal cells by stimulating phospholipase C-mediated inositol 1,4,5-trisphosphate productionViral Membrane Channels: Role and Function in the Virus Life CycleThe actin cytoskeleton as a barrier to virus infection of polarized epithelial cellsMembrane permeabilization by small hydrophobic nonstructural proteins of Japanese encephalitis virus.Evaluation of serum antibody responses against the rotavirus nonstructural protein NSP4 in children after rhesus rotavirus tetravalent vaccination or natural infection.Activation of the endoplasmic reticulum calcium sensor STIM1 and store-operated calcium entry by rotavirus requires NSP4 viroporin activity.Rotavirus infection reduces sucrase-isomaltase expression in human intestinal epithelial cells by perturbing protein targeting and organization of microvillar cytoskeleton.Expression of nonstructural rotavirus protein NSP4 mimics Ca2+ homeostasis changes induced by rotavirus infection in cultured cells.BiP (GRP78) and endoplasmin (GRP94) are induced following rotavirus infection and bind transiently to an endoplasmic reticulum-localized virion componentRotavirus infection induces cytoskeleton disorganization in human intestinal epithelial cells: implication of an increase in intracellular calcium concentration.Rotavirus infection induces an increase in intracellular calcium concentration in human intestinal epithelial cells: role in microvillar actin alteration.NSP4 enterotoxin of rotavirus induces paracellular leakage in polarized epithelial cellsRotavirus stimulates release of serotonin (5-HT) from human enterochromaffin cells and activates brain structures involved in nausea and vomitingNSP4 gene analysis of rotaviruses recovered from infected children with and without diarrhea.How do the rotavirus NSP4 and bacterial enterotoxins lead differently to diarrhea?Immobilization of the early secretory pathway by a virus glycoprotein that binds to microtubulesIntestinal epithelial responses to enteric pathogens: effects on the tight junction barrier, ion transport, and inflammation.The concentration of Ca2+ that solubilizes outer capsid proteins from rotavirus particles is dependent on the strainThe rotavirus nonstructural glycoprotein NSP4 possesses membrane destabilization activity.Poliovirus protein 2BC increases cytosolic free calcium concentrations.Genetic divergence of rotavirus nonstructural protein 4 results in distinct serogroup-specific viroporin activity and intracellular punctate structure morphologies.Rotavirus and Serotonin Cross-Talk in DiarrhoeaThe formation of viroplasm-like structures by the rotavirus NSP5 protein is calcium regulated and directed by a C-terminal helical domainAutophagy hijacked through viroporin-activated calcium/calmodulin-dependent kinase kinase-β signaling is required for rotavirus replicationRotavirus nonstructural glycoprotein NSP4 alters plasma membrane permeability in mammalian cells.Mutational analysis of the rotavirus NSP4 enterotoxic domain that binds to caveolin-1.Silencing of rotavirus NSP4 or VP7 expression reduces alterations in Ca2+ homeostasis induced by infection of cultured cells.Novel pentameric structure of the diarrhea-inducing region of the rotavirus enterotoxigenic protein NSP4.Coxsackievirus protein 2B modifies endoplasmic reticulum membrane and plasma membrane permeability and facilitates virus release.Characterization of a membrane calcium pathway induced by rotavirus infection in cultured cells.Mutations in rotavirus nonstructural glycoprotein NSP4 are associated with altered virus virulence.Carbohydrates facilitate correct disulfide bond formation and folding of rotavirus VP7A functional NSP4 enterotoxin peptide secreted from rotavirus-infected cells.Gene expression pattern in Caco-2 cells following rotavirus infection.Selective depletion of stored calcium by thapsigargin blocks rotavirus maturation but not the cytopathic effect.Enhanced intracellular calcium concentration during poliovirus infection.The rotavirus nonstructural glycoprotein NSP4 mobilizes Ca2+ from the endoplasmic reticulum.
P2860
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P2860
The nonstructural glycoprotein of rotavirus affects intracellular calcium levels
description
1994 nî lūn-bûn
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1994年の論文
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1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
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1994年論文
@zh-tw
1994年论文
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1994年论文
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1994年论文
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name
The nonstructural glycoprotein of rotavirus affects intracellular calcium levels
@ast
The nonstructural glycoprotein of rotavirus affects intracellular calcium levels
@en
type
label
The nonstructural glycoprotein of rotavirus affects intracellular calcium levels
@ast
The nonstructural glycoprotein of rotavirus affects intracellular calcium levels
@en
prefLabel
The nonstructural glycoprotein of rotavirus affects intracellular calcium levels
@ast
The nonstructural glycoprotein of rotavirus affects intracellular calcium levels
@en
P2093
P2860
P1433
P1476
The nonstructural glycoprotein of rotavirus affects intracellular calcium levels
@en
P2093
P2860
P304
P407
P577
1994-01-01T00:00:00Z