Augmentation of late sodium current unmasks the proarrhythmic effects of amiodarone.
about
Multiple arrhythmic syndromes in a newborn, owing to a novel mutation in SCN5ADrugs and Brugada syndrome patients: review of the literature, recommendations, and an up-to-date website (www.brugadadrugs.org)The role of late I Na in development of cardiac arrhythmiasRegulation of intracellular Na(+) in health and disease: pathophysiological mechanisms and implications for treatmentClinical and genetic determinants of torsade de pointes riskElectrocardiographic Biomarkers for Detection of Drug-Induced Late Sodium Current BlockAutomated Algorithm for J-Tpeak and Tpeak-Tend Assessment of Drug-Induced Proarrhythmia RiskLate sodium current contributes to the reverse rate-dependent effect of IKr inhibition on ventricular repolarization.Late sodium current block for drug-induced long QT syndrome: Results from a prospective clinical trialInhibition of late sodium current suppresses calcium-related ventricular arrhythmias by reducing the phosphorylation of CaMK-II and sodium channel expressionsElectrophysiologic basis for the antiarrhythmic actions of ranolazine.Novel pharmacological targets for the rhythm control management of atrial fibrillation.Flexible and waterproof micro-sensors to uncover zebrafish circadian rhythms: The next generation of cardiac monitoring for drug screening.Quantitative Profiling of the Effects of Vanoxerine on Human Cardiac Ion Channels and its Application to Cardiac Risk.The virtual heart as a platform for screening drug cardiotoxicity.Role of late sodium current as a potential arrhythmogenic mechanism in the progression of pressure-induced heart disease.Role of late sodium current in modulating the proarrhythmic and antiarrhythmic effects of quinidinePotent antiarrhythmic effects of chronic amiodarone in canine pulmonary vein sleeve preparationsThe arrhythmogenic consequences of increasing late INa in the cardiomyocyte.Population pharmacokinetics and electrocardiographic effects of dihydroartemisinin-piperaquine in healthy volunteers.Effects of Amiodarone and N-desethylamiodarone on Cardiac Voltage-Gated Sodium Channels.Effect of intravenous amiodarone on QT and T peak-T end dispersions in patients with nonischemic heart failure treated with cardiac resynchronization-defibrillator therapy and electrical storm.Mechanistic Model-Informed Proarrhythmic Risk Assessment of Drugs: Review of the "CiPA" Initiative and Design of a Prospective Clinical Validation Study.Turbulent electrical activity at sharp-edged inexcitable obstacles in a model for human cardiac tissue.Inhibition of the K+ conductance and Cole-Moore shift of the oncogenic Kv10.1 channel by amiodarone.Late sodium current associated cardiac electrophysiological and mechanical dysfunction.Beat-to-beat variability of cardiac action potential duration: underlying mechanism and clinical implications.Differentiating drug-induced multichannel block on the electrocardiogram: randomized study of dofetilide, quinidine, ranolazine, and verapamil.Improving the assessment of heart toxicity for all new drugs through translational regulatory science.
P2860
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P2860
Augmentation of late sodium current unmasks the proarrhythmic effects of amiodarone.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Augmentation of late sodium current unmasks the proarrhythmic effects of amiodarone.
@ast
Augmentation of late sodium current unmasks the proarrhythmic effects of amiodarone.
@en
type
label
Augmentation of late sodium current unmasks the proarrhythmic effects of amiodarone.
@ast
Augmentation of late sodium current unmasks the proarrhythmic effects of amiodarone.
@en
prefLabel
Augmentation of late sodium current unmasks the proarrhythmic effects of amiodarone.
@ast
Augmentation of late sodium current unmasks the proarrhythmic effects of amiodarone.
@en
P2093
P2860
P356
P1476
Augmentation of late sodium current unmasks the proarrhythmic effects of amiodarone
@en
P2093
Jeremy Ruskin
John C Shryock
Luiz Belardinelli
Sridharan Rajamani
P2860
P304
P356
10.1093/CVR/CVM069
P577
2007-11-13T00:00:00Z