Late sodium current contributes to the reverse rate-dependent effect of IKr inhibition on ventricular repolarization.
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The role of late I Na in development of cardiac arrhythmiasThe late Na+ current--origin and pathophysiological relevanceLate Na(+) current and protracted electrical recovery are critical determinants of the aging myopathyPost-translational modifications of the cardiac Na channel: contribution of CaMKII-dependent phosphorylation to acquired arrhythmiasExperimentally-Based Computational Investigation into Beat-To-Beat Variability in Ventricular Repolarization and Its Response to Ionic Current Inhibitionα1-Syntrophin Variant Identified in Drug-Induced Long QT Syndrome Increases Late Sodium CurrentPopulation of computational rabbit-specific ventricular action potential models for investigating sources of variability in cellular repolarisationSimulation and mechanistic investigation of the arrhythmogenic role of the late sodium current in human heart failureThe cardiac L-type calcium channel distal carboxy terminus autoinhibition is regulated by calcium.Voltage-Gated Sodium Channel Phosphorylation at Ser571 Regulates Late Current, Arrhythmia, and Cardiac Function In Vivo.18β-Glycyrrhetinic acid preferentially blocks late Na current generated by ΔKPQ Nav1.5 channels.Inhibition of late sodium current suppresses calcium-related ventricular arrhythmias by reducing the phosphorylation of CaMK-II and sodium channel expressionsRestitution slope is principally determined by steady-state action potential duration.Effects of ranolazine on torsades de pointes tachycardias in a healthy isolated rabbit heart modelNonequilibrium reactivation of Na+ current drives early afterdepolarizations in mouse ventricleThe virtual heart as a platform for screening drug cardiotoxicity.The high frequency relationship: implications for torsadogenic hERG blockers.Myocyte repolarization modulates myocardial function in aging dogsProarrhythmic and Torsadogenic Effects of Potassium Channel Blockers in Patients.The arrhythmogenic consequences of increasing late INa in the cardiomyocyte.In silico assessment of drug safety in human heart applied to late sodium current blockersResveratrol protects rabbit ventricular myocytes against oxidative stress-induced arrhythmogenic activity and Ca2+ overload.Ranolazine: an antianginal drug with antiarrhythmic properties.Deranged sodium to sudden death.Geometrical considerations in cardiac electrophysiology and arrhythmogenesis.Role of abnormal repolarization in the mechanism of cardiac arrhythmia.Intracellular calcium attenuates late current conducted by mutant human cardiac sodium channels.Use-Dependent Block of Human Cardiac Sodium Channels by GS967.ICaL and Ito mediate rate-dependent repolarization in rabbit atrial myocytes.Late sodium current associated cardiac electrophysiological and mechanical dysfunction.Inhibition of the α-Subunit of Phosphoinositide 3-Kinase in Heart Increases Late Sodium Current and Is Arrhythmogenic.Late sodium current inhibitors to treat exercise-induced obstruction in hypertrophic cardiomyopathy: an in vitro study in human myocardium.
P2860
Q26823149-11F7E4B5-EBF1-4B8C-9C12-7E1B36AD2CF1Q26864515-78533924-733E-4FA4-8D82-63AE9C9229A5Q27318671-3D51B04E-FBE8-4354-A10A-6A0FC553DC9FQ28292930-7125571D-1755-4959-B112-706FD9ABD547Q28551018-636329F9-4A5A-4071-9EE8-7C2AAC7C7533Q28551060-89556C3C-08C4-4BB1-9488-EB3ABF101680Q28658394-531FA566-EAFD-4143-83A3-7616938DF07AQ28731387-5E8B575F-3513-4C28-94EA-C5A86526AB6FQ30414950-04D90946-4BE4-4535-95C7-EA241859F10AQ30973910-B03E41AF-AF04-44A0-ACCA-E64477EAE22BQ33567494-83C02752-EB1F-41F0-83D9-C3E6B8032D8FQ33681289-A82F47E2-7D69-4F97-9786-15F0EA8353D2Q33705744-7CE985B4-CD20-4458-90E4-26C9A72A9C07Q34853000-90E03CC2-0004-4A07-938D-9FD7DE8CD064Q34994127-D8630F5C-8176-4C1C-9344-115F0B856427Q36342116-6DE84E09-A142-4A80-B77A-D869BC2E3709Q36506873-C550EFED-5D44-4617-89BA-D1FCEC17E0EDQ36902443-264BF197-B26E-4BE0-9516-B46DFD247B8AQ36970774-BC6F23C0-F6A6-41E4-B897-70A16D2597D4Q37345048-94578984-F5F0-4C9A-9EEB-0688CAA7310AQ37706949-97B02D2A-9F48-4907-B48D-93E4F63CFD63Q37729590-F5CACEC4-4CD8-4098-A76F-94FC620A94A2Q37910205-1A054571-61DE-41CB-8AFA-340BB399A7B9Q38378616-82155C4B-808B-4787-8950-B2DBCDF7BBE3Q38639128-E30BCF4C-3D83-4086-8D08-AD96759BBDFBQ39434566-B359CED5-49CE-4217-A511-E0713475BA03Q42234927-E2374726-51F8-43A9-88A6-09CC03806407Q47435102-4F727598-4E33-44FE-B168-5CEC765AF241Q49832660-560707C5-0151-4004-B776-F67F34B39713Q50061975-8127E6C7-FB5B-47D7-BDE2-B4E4BDB227A9Q52644018-D8FD71AE-2F6A-441D-BD2E-5CBD73485724Q55410018-1F66CB7E-733B-4DF0-B11B-93EC87DEB487
P2860
Late sodium current contributes to the reverse rate-dependent effect of IKr inhibition on ventricular repolarization.
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Late sodium current contribute ...... on ventricular repolarization.
@ast
Late sodium current contribute ...... on ventricular repolarization.
@en
type
label
Late sodium current contribute ...... on ventricular repolarization.
@ast
Late sodium current contribute ...... on ventricular repolarization.
@en
prefLabel
Late sodium current contribute ...... on ventricular repolarization.
@ast
Late sodium current contribute ...... on ventricular repolarization.
@en
P2093
P2860
P1433
P1476
Late sodium current contribute ...... on ventricular repolarization.
@en
P2093
John C Shryock
Luiz Belardinelli
Peihua Zhang
P2860
P304
P356
10.1161/CIRCULATIONAHA.110.000661
P407
P577
2011-04-11T00:00:00Z