Specific interaction between the bovine papillomavirus E5 transforming protein and the beta receptor for platelet-derived growth factor in stably transformed and acutely transfected cells
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Association of insulin receptor substrate 1 with simian virus 40 large T antigenPhosphotyrosine binding domain-dependent upregulation of the platelet-derived growth factor receptor alpha signaling cascade by transforming mutants of Cbl: implications for Cbl's function and oncogenicityArtificial transmembrane oncoproteins smaller than the bovine papillomavirus E5 protein redefine sequence requirements for activation of the platelet-derived growth factor beta receptor.Bovine papillomavirus E5 protein induces oligomerization and trans-phosphorylation of the platelet-derived growth factor beta receptor.A single amino acid substitution in a WW-like domain of diverse members of the PDGF receptor subfamily of tyrosine kinases causes constitutive receptor activation.Structural role of the conserved cysteines in the dimerization of the viral transmembrane oncoprotein E5.The E5 proteinsMultiple transmembrane amino acid requirements suggest a highly specific interaction between the bovine papillomavirus E5 oncoprotein and the platelet-derived growth factor beta receptor.Viral miniproteinsPapillomavirus E5: the smallest oncoprotein with many functions.The Epstein-Barr virus LMP1 cytoplasmic carboxy terminus is essential for B-lymphocyte transformation; fibroblast cocultivation complements a critical function within the terminal 155 residues.Mutational analysis of the interaction between the bovine papillomavirus E5 transforming protein and the endogenous beta receptor for platelet-derived growth factor in mouse C127 cells.Mutational analysis of the beta-type platelet-derived growth factor receptor defines the site of interaction with the bovine papillomavirus type 1 E5 transforming protein.Effect of human papillomavirus type 16 oncogenes on MAP kinase activity.E5 oncoprotein transmembrane mutants dissociate fibroblast transforming activity from 16-kilodalton protein binding and platelet-derived growth factor receptor binding and phosphorylation.Identification of amino acids in the transmembrane and juxtamembrane domains of the platelet-derived growth factor receptor required for productive interaction with the bovine papillomavirus E5 protein.Hydrophobic Mismatch Drives the Interaction of E5 with the Transmembrane Segment of PDGF Receptor.Ligand-independent activation of the platelet-derived growth factor beta receptor: requirements for bovine papillomavirus E5-induced mitogenic signaling.The bovine papillomavirus type 1 E5 transforming protein specifically binds and activates the beta-type receptor for the platelet-derived growth factor but not other related tyrosine kinase-containing receptors to induce cellular transformation.The bovine papillomavirus E5 protein and the PDGF beta receptor: it takes two to tango.LMP-1 activates NF-kappa B by targeting the inhibitory molecule I kappa B alpha.Compensatory mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor β receptor reveal a complex direct transmembrane interaction.Polyomavirus large T antigen induces alterations in cytoplasmic signalling pathways involving Shc activation.Role of glutamine 17 of the bovine papillomavirus E5 protein in platelet-derived growth factor beta receptor activation and cell transformation.Human papillomavirus type 16 E5 protein affects cell-cell communication in an epithelial cell lineFailure of the bovine papillomavirus to transform mouse embryo fibroblasts with a targeted disruption of the insulin-like growth factor I receptor genes.Productive interaction between transmembrane mutants of the bovine papillomavirus E5 protein and the platelet-derived growth factor beta receptor.Upregulation of swelling-activated Cl- channel sensitivity to cell volume by activation of EGF receptors in murine mammary cells.Golgi alkalinization by the papillomavirus E5 oncoprotein.Two transmembrane dimers of the bovine papillomavirus E5 oncoprotein clamp the PDGF β receptor in an active dimeric conformation.
P2860
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P2860
Specific interaction between the bovine papillomavirus E5 transforming protein and the beta receptor for platelet-derived growth factor in stably transformed and acutely transfected cells
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1994 nî lūn-bûn
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1994年の論文
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1994年論文
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1994年論文
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1994年論文
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1994年論文
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1994年論文
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1994年论文
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1994年论文
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1994年论文
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name
Specific interaction between t ...... and acutely transfected cells
@ast
Specific interaction between t ...... and acutely transfected cells
@en
type
label
Specific interaction between t ...... and acutely transfected cells
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Specific interaction between t ...... and acutely transfected cells
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prefLabel
Specific interaction between t ...... and acutely transfected cells
@ast
Specific interaction between t ...... and acutely transfected cells
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P2860
P1433
P1476
Specific interaction between t ...... and acutely transfected cells
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P2093
P2860
P304
P407
P577
1994-06-01T00:00:00Z