about
A comparative analysis of the aggregation behavior of amyloid-β peptide variantsOverview of Alzheimer's Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal CompoundsNeuropsychiatric Disturbances in Alzheimer's Disease: What Have We Learned from Neuropathological Studies?Toxin-Induced Experimental Models of Learning and Memory ImpairmentCopper chelator induced efficient episodic memory recovery in a non-transgenic Alzheimer's mouse modelPharmacological characterization of memoquin, a multi-target compound for the treatment of Alzheimer's diseaseAnimal models for Alzheimer's disease and frontotemporal dementia: a perspectiveRemoving obstacles in neuroscience drug discovery: the future path for animal models.Factor V activator from Daboia russelli russelli venom destabilizes β-amyloid aggregate, the hallmark of Alzheimer disease.Differences in memory development among C57BL/6NCrl, 129S2/SvPasCrl, and FVB/NCrl mice after delay and trace fear conditioning.Role of the macrophage inflammatory protein-1alpha/CC chemokine receptor 5 signaling pathway in the neuroinflammatory response and cognitive deficits induced by beta-amyloid peptideAlzheimer's disease: pathophysiology and applications of magnetic nanoparticles as MRI theranostic agents.In vivo 1H-magnetic resonance spectroscopy can detect metabolic changes in APP/PS1 mice after donepezil treatmentConvergence of amyloid-beta and tau pathologies on mitochondria in vivo.7.0T nuclear magnetic resonance evaluation of the amyloid beta (1-40) animal model of Alzheimer's disease: comparison of cytology verification.Increased Cerebrospinal Fluid Production as a Possible Mechanism Underlying Caffeine's Protective Effect against Alzheimer's DiseaseAnimal models in the drug discovery pipeline for Alzheimer's diseaseUnfolded Protein Response and PERK Kinase as a New Therapeutic Target in the Pathogenesis of Alzheimer's Disease3,6'-Dithiothalidomide, a new TNF-α synthesis inhibitor, attenuates the effect of Aβ1-42 intracerebroventricular injection on hippocampal neurogenesis and memory deficit.Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau proteinAmyloid-beta aggregation.Modeling Alzheimer's disease: from past to futureAn update of animal models of Alzheimer disease with a reevaluation of plaque depositions.Pharmacogenetic basis for therapeutic optimization in Alzheimer's disease.A longitudinal study of behavioral deficits in an AβPP transgenic mouse model of Alzheimer's disease.Advances on the understanding of the origins of synaptic pathology in AD.Comparative neurotoxicity screening in human iPSC-derived neural stem cells, neurons and astrocytesImpairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model.The role of adenosine in Alzheimer's diseaseDevelopment of an in-vivo active reversible butyrylcholinesterase inhibitor.Cross currents in protein misfolding disorders: interactions and therapy.Emerging cognitive enhancing drugs.APP transgenic mice: their use and limitations.Combating neurodegenerative disease with chemical probes and model systems.Battling Alzheimer's Disease: Targeting SUMOylation-Mediated Pathways.Mitochondrial dysfunction: the missing link between aging and sporadic Alzheimer's disease.Non human primate models for Alzheimer's disease-related research and drug discovery.Challenges with in vitro and in vivo experimental models of urinary bladder cancer for novel drug discovery.Intranasal H102 Peptide-Loaded Liposomes for Brain Delivery to Treat Alzheimer's Disease.Rosiglitazone rescues memory impairment in Alzheimer's transgenic mice: mechanisms involving a reduced amyloid and tau pathology.
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Drug discovery in dementia: the role of rodent models.
@ast
Drug discovery in dementia: the role of rodent models.
@en
type
label
Drug discovery in dementia: the role of rodent models.
@ast
Drug discovery in dementia: the role of rodent models.
@en
prefLabel
Drug discovery in dementia: the role of rodent models.
@ast
Drug discovery in dementia: the role of rodent models.
@en
P356
P1476
Drug discovery in dementia: the role of rodent models.
@en
P2093
Debby Van Dam
Peter Paul De Deyn
P2888
P304
P356
10.1038/NRD2075
P577
2006-11-01T00:00:00Z