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The neurotrophic compound J147 reverses cognitive impairment in aged Alzheimer's disease miceProtein phosphatase 5 protects neurons against amyloid-beta toxicityExpression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretaseTransmission and spreading of tauopathy in transgenic mouse brainAmyloids: friend or foe?Induction of tau pathology by intracerebral infusion of amyloid-beta -containing brain extract and by amyloid-beta deposition in APP x Tau transgenic mice18F PET ligands for the early diagnosis of Alzheimer’s disease dementia and other dementias in people with mild cognitive impairment (MCI)Drug Design for CNS Diseases: Polypharmacological Profiling of Compounds Using Cheminformatic, 3D-QSAR and Virtual Screening MethodologiesOverview of Alzheimer's Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal CompoundsDiagnostic Value of microRNA for Alzheimer's Disease: A Systematic Review and Meta-AnalysisThere's Something Wrong with my MAM; the ER-Mitochondria Axis and Neurodegenerative DiseasesTurning On Lights to Stop Neurodegeneration: The Potential of Near Infrared Light Therapy in Alzheimer's and Parkinson's DiseasePET Imaging of Epigenetic Influences on Alzheimer's DiseaseKynurenine 3-Monooxygenase: An Influential Mediator of NeuropathologyDoes neuroinflammation turn on the flame in Alzheimer's disease? Focus on astrocytesEnvironmental pollutants as risk factors for neurodegenerative disorders: Alzheimer and Parkinson diseasesGlu504Lys Single Nucleotide Polymorphism of Aldehyde Dehydrogenase 2 Gene and the Risk of Human DiseasesRaf kinase inhibitory protein (RKIP): functional pleiotropy in the mammalian brainLink between type 2 diabetes and Alzheimer's disease: from epidemiology to mechanism and treatmentPreclinical Alzheimer disease: identification of cases at risk among cognitively intact older individualsDisrupting self-assembly and toxicity of amyloidogenic protein oligomers by "molecular tweezers" - from the test tube to animal modelsThe role of tau in neurodegenerative diseases and its potential as a therapeutic targetInvited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimagingCerebrospinal fluid and blood biomarkers in Alzheimer's diseaseGenome-wide screen for modifiers of ataxin-3 neurodegeneration in DrosophilaNeurodegeneration in a Drosophila model for the function of TMCC2, an amyloid protein precursor-interacting and apolipoprotein E-binding proteinNeuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer's disease model.Behavioral stress fails to accelerate the onset and progression of plaque pathology in the brain of a mouse model of Alzheimer's diseaseStructure of a Protein Phosphatase 2A Holoenzyme: Insights into B55-Mediated Tau DephosphorylationStructure-Based Design of Highly Selective β-Secretase Inhibitors: Synthesis, Biological Evaluation, and Protein–Ligand X-ray Crystal StructureTargeting mRNA for Alzheimer's and related dementias.Spines, plasticity, and cognition in Alzheimer's model miceTau Biology and Tau-Directed Therapies for Alzheimer's DiseaseREM sleep and its Loss-Associated Epigenetic Regulation with Reference to Noradrenaline in ParticularOcular indicators of Alzheimer's: exploring disease in the retinaThe preclinical phase of the pathological process underlying sporadic Alzheimer's diseaseEngineering enhanced protein disaggregases for neurodegenerative diseaseIn vitro Pb exposure disturbs the balance between Aβ production and elimination: the role of AβPP and neprilysinGenetic determinants of human health span and life span: progress and new opportunitiesStructural polymorphism of 441-residue tau at single residue resolution
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
A century of Alzheimer's disease.
@ast
A century of Alzheimer's disease.
@en
type
label
A century of Alzheimer's disease.
@ast
A century of Alzheimer's disease.
@en
prefLabel
A century of Alzheimer's disease.
@ast
A century of Alzheimer's disease.
@en
P356
P1433
P1476
A century of Alzheimer's disease.
@en
P2093
Maria Grazia Spillantini
Michel Goedert
P304
P356
10.1126/SCIENCE.1132814
P407
P577
2006-11-01T00:00:00Z