about
Alterations of the intracellular peptidome in response to the proteasome inhibitor bortezomibCaspase-8 and caspase-7 sequentially mediate proteolytic activation of acid sphingomyelinase in TNF-R1 receptosomesA pathway sensor for genome-wide screens of intracellular proteolytic cleavageGlobal mapping of the topography and magnitude of proteolytic events in apoptosisCaspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)-mediated inhibition of caspase 9Protease signalling: the cutting edgeStructural basis for executioner caspase recognition of P5 position in substratesMetacaspase Yca1 is required for clearance of insoluble protein aggregates.PAC-1 activates procaspase-3 in vitro through relief of zinc-mediated inhibitionProcaspase-3 activation as an anti-cancer strategy: structure-activity relationship of procaspase-activating compound 1 (PAC-1) and its cellular co-localization with caspase-3Reevesioside F induces potent and efficient anti-proliferative and apoptotic activities through Na⁺/K⁺-ATPase α3 subunit-involved mitochondrial stress and amplification of caspase cascadesVersatile assays for high throughput screening for activators or inhibitors of intracellular proteases and their cellular regulatorsA whole cell assay to measure caspase-6 activity by detecting cleavage of lamin A/CProteome-wide substrate analysis indicates substrate exclusion as a mechanism to generate caspase-7 versus caspase-3 specificityAmplification of CD95 activation by caspase 8-induced endosomal acidification in rat hepatocytesA quantitative method for the specific assessment of caspase-6 activity in cell cultureApoptotic DNA degradation into oligonucleosomal fragments, but not apoptotic nuclear morphology, relies on a cytosolic pool of DFF40/CAD endonucleasePannexin 1 channels mediate 'find-me' signal release and membrane permeability during apoptosisDiffusion is capable of translating anisotropic apoptosis initiation into a homogeneous execution of cell deathLocal caspase activation interacts with Slit-Robo signaling to restrict axonal arborization.A multi-factor model for caspase degradome predictionPhotodynamic therapy combined to cisplatin potentiates cell death responses of cervical cancer cells.A sequence and structure based method to predict putative substrates, functions and regulatory networks of endo proteases.Combined suppression of CASP2 and CASP6 protects retinal ganglion cells from apoptosis and promotes axon regeneration through CNTF-mediated JAK/STAT signalling.Structural and kinetic determinants of protease substratesCaspase-7 cleavage of Kaposi sarcoma-associated herpesvirus ORF57 confers a cellular function against viral lytic gene expression.Protection of retinal ganglion cells by caspase substrate-binding peptide IQACRG from N-methyl-D-aspartate receptor-mediated excitotoxicity.Analysis of mouse brain peptides using mass spectrometry-based peptidomics: implications for novel functions ranging from non-classical neuropeptides to microproteins.Drosophila IAP1-mediated ubiquitylation controls activation of the initiator caspase DRONC independent of protein degradation.Mechanism of tyrosine phosphorylation of procaspase-9 and Apaf-1 in cytosolic fractions of the cerebral cortex of newborn piglets during hypoxia.iGLuc: a luciferase-based inflammasome and protease activity reporter.Caspase-1 recognizes extended cleavage sites in its natural substratesPreparation of the caspase-3/7 substrate Ac-DEVD-pNA by solution-phase peptide synthesisRegulation of the Apaf-1-caspase-9 apoptosomeHLJ1 is a novel caspase-3 substrate and its expression enhances UV-induced apoptosis in non-small cell lung carcinomaGestational diabetes mellitus alters apoptotic and inflammatory gene expression of trophobasts from human term placentaEmerging principles in protease-based drug discovery.Caspase cleavage sites in the human proteome: CaspDB, a database of predicted substrates.TRAIL treatment provokes mutations in surviving cells.Human caspases: activation, specificity, and regulation
P2860
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P2860
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Caspase substrates.
@ast
Caspase substrates.
@en
type
label
Caspase substrates.
@ast
Caspase substrates.
@en
prefLabel
Caspase substrates.
@ast
Caspase substrates.
@en
P356
P1476
Caspase substrates.
@en
P2093
Salvesen GS
P2888
P356
10.1038/SJ.CDD.4402059
P577
2006-11-03T00:00:00Z