A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase.
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Function, regulation and pathological roles of the Gab/DOS docking proteinsInteraction of the tyrosine phosphatase SHP-2 with Gab2 regulates Rho-dependent activation of the c-fos serum response element by interleukin-2Adapter function of protein-tyrosine phosphatase 1D in insulin receptor/insulin receptor substrate-1 interactionPhosphorylation of receptor protein-tyrosine phosphatase alpha on Tyr789, a binding site for the SH3-SH2-SH3 adaptor protein GRB-2 in vivoCharacterization of phosphotyrosine binding motifs in the cytoplasmic domain of platelet/endothelial cell adhesion molecule-1 (PECAM-1) that are required for the cellular association and activation of the protein-tyrosine phosphatase, SHP-2Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathwayA novel role for Gab1 and SHP2 in epidermal growth factor-induced Ras activationRapid identification of phosphopeptide ligands for SH2 domains. Screening of peptide libraries by fluorescence-activated bead sortingTyrosine phosphorylation of an SH2-containing protein tyrosine phosphatase is coupled to platelet thrombin receptor via a pertussis toxin-sensitive heterotrimeric G-proteinThe LAR transmembrane protein tyrosine phosphatase and a coiled-coil LAR-interacting protein co-localize at focal adhesionsActivation of protein-tyrosine phosphatase SH-PTP2 by a tyrosine-based activation motif of a novel brain moleculeTyrosine phosphorylation of the c-cbl proto-oncogene protein product and association with epidermal growth factor (EGF) receptor upon EGF stimulationGAREM, a novel adaptor protein for growth factor receptor-bound protein 2, contributes to cellular transformation through the activation of extracellular signal-regulated kinase signalingBinding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiationInterleukin-6-type cytokine signalling through the gp130/Jak/STAT pathwayReceptor protein tyrosine phosphatase alpha participates in the m1 muscarinic acetylcholine receptor-dependent regulation of Kv1.2 channel activityTight association of GRB2 with receptor protein-tyrosine phosphatase alpha is mediated by the SH2 and C-terminal SH3 domainsProtein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to RasWiskott-Aldrich syndrome protein is associated with the adapter protein Grb2 and the epidermal growth factor receptor in living cellsTyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activationStimulation of phosphatidylinositol 3-kinase by fibroblast growth factor receptors is mediated by coordinated recruitment of multiple docking proteinsTyrosine phosphorylation of Grb2-associated proteins correlates with phospholipase C gamma 1 activation in T cellsEnhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptorBiochemical and Functional Insights into the Integrated Regulation of Innate Immune Cell Responses by Teleost Leukocyte Immune-Type ReceptorsAssembly and function of a cytosolic form of NADH-specific isocitrate dehydrogenase in yeast.Tyrosyl phosphorylation of Shp2 is required for normal ERK activation in response to some, but not all, growth factorsAssociation of atypical protein kinase C isotypes with the docker protein FRS2 in fibroblast growth factor signalingBrain-derived neurotrophic factor stimulates interactions of Shp2 with phosphatidylinositol 3-kinase and Grb2 in cultured cerebral cortical neuronsThrombopoietin induces phosphoinositol 3-kinase activation through SHP2, Gab, and insulin receptor substrate proteins in BAF3 cells and primary murine megakaryocytesThe transmembranal and cytoplasmic forms of protein tyrosine phosphatase epsilon physically associate with the adaptor molecule Grb2SHP-2 is involved in heterodimer specific loss of phosphorylation of Tyr771 in the PDGF beta-receptorFibroblast growth factor signaling in Caenorhabditis elegansChoice of STATs and other substrates specified by modular tyrosine-based motifs in cytokine receptorsInterleukin-3 induces the association of the inositol 5-phosphatase SHIP with SHP2The platelet-derived growth factor beta receptor triggers multiple cytoplasmic signaling cascades that arrive at the nucleus as distinguishable inputsGrb2 forms an inducible protein complex with CD28 through a Src homology 3 domain-proline interactionThe tyrosine phosphatase PTP1C associates with Vav, Grb2, and mSos1 in hematopoietic cellsPhosphotyrosine 1173 mediates binding of the protein-tyrosine phosphatase SHP-1 to the epidermal growth factor receptor and attenuation of receptor signalingEpidermal growth factor induces coupling of protein-tyrosine phosphatase 1D to GRB2 via the COOH-terminal SH3 domain of GRB2Involvement of SH2-containing phosphotyrosine phosphatase Syp in erythropoietin receptor signal transduction pathways
P2860
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P2860
A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase.
description
1994 nî lūn-bûn
@nan
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
1994年论文
@zh
1994年论文
@zh-cn
name
A new function for a phosphoty ...... to a receptor tyrosine kinase.
@ast
A new function for a phosphoty ...... to a receptor tyrosine kinase.
@en
type
label
A new function for a phosphoty ...... to a receptor tyrosine kinase.
@ast
A new function for a phosphoty ...... to a receptor tyrosine kinase.
@en
prefLabel
A new function for a phosphoty ...... to a receptor tyrosine kinase.
@ast
A new function for a phosphoty ...... to a receptor tyrosine kinase.
@en
P2093
P2860
P356
P1476
A new function for a phosphoty ...... to a receptor tyrosine kinase.
@en
P2093
A G Batzer
A Kashishian
J A Cooper
J Schlessinger
R Nishimura
P2860
P304
P356
10.1128/MCB.14.1.509
P407
P577
1994-01-01T00:00:00Z