The bisphosphonate zoledronic acid impairs Ras membrane [correction of impairs membrane] localisation and induces cytochrome c release in breast cancer cells.
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Enhanced anti-tumor effect of zoledronic acid combined with temozolomide against human malignant glioma cell expressing O6-methylguanine DNA methyltransferaseZoledronic acid treatment impairs protein geranyl-geranylation for biological effects in prostatic cells.Direct antitumour activity of zoledronic acid: preclinical and clinical data.The role of zoledronic acid in the adjuvant treatment of breast cancer: current perspectives.In vivo effects of zoledronic acid on oral mucosal epithelial cellsAdditive growth inhibitory effects of ibandronate and antiestrogens in estrogen receptor-positive breast cancer cell lines.NCCN Task Force Report: Bone Health in Cancer Care.Tumour macrophages as potential targets of bisphosphonates.The use of zoledronic acid in the management of metastatic bone disease and hypercalcaemia.Advances in the use of bisphosphonates in the prostate cancer setting.The enhancing effect of a laser photochemotherapy with cisplatin or zolendronic acid in primary human osteoblasts and osteosarcoma cells in vitro.Zoledronic acid exerts its antitumor effect in multiple myeloma interfering with the bone marrow microenvironment.Zoledronic acid inhibits aromatase activity and phosphorylation: potential mechanism for additive zoledronic acid and letrozole drug interactionBiphosphonates in advanced prostate and renal cell cancer--current status and potential applications.Inhibition of breast cancer cell proliferation in repeated and non-repeated treatment with zoledronic acid.New insights into the actions of bisphosphonate zoledronic acid in breast cancer cells by dual RhoA-dependent and -independent effects.Immunomodulating role of bisphosphonates on human gamma delta T cells: an intriguing and promising aspect of their antitumour activity.Zoledronic acid reverses the epithelial-mesenchymal transition and inhibits self-renewal of breast cancer cells through inactivation of NF-κBApoptosis repressor with caspase recruitment domain enhances survival and promotes osteogenic differentiation of human osteoblast cells under Zoledronate treatment.Zoledronic acid induces antiproliferative and apoptotic effects in human pancreatic cancer cells in vitro.An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis.Zoledronic acid: an unending tale for an antiresorptive agent.New perspectives on zoledronic acid in breast cancer: potential augmentation of anticancer immune response.Antiangiogenic effects of zoledronate on cancer neovasculature.Beyond aspirin-cancer prevention with statins, metformin and bisphosphonates.Effects of bisphosphonates on human esophageal squamous cell carcinoma cell survival.Effects of zoledronic acid and docetaxel on small GTP-binding proteins in prostate cancer.YM-175 induces apoptosis of human native monocyte-lineage cells via inhibition of prenylation.Differential effects of ibandronate, docetaxel and farnesol treatment alone and in combination on the growth of prostate cancer cell lines.The in vitro anti-tumour activity of zoledronic acid and docetaxel at clinically achievable concentrations in prostate cancer.Zoledronic acid (Zometa) enhances the cytotoxic effect of gemcitabine and fluvastatin: in vitro isobologram studies with conventional and nonconventional cytotoxic agents.Zoledronic acid induces apoptosis and inhibits adhesion to mineralized matrix in prostate cancer cells via inhibition of protein prenylation.Bisphosphonates and cancer: what opportunities from nanotechnology?Nitrogen-containing bisphosphonates inhibit cell cycle progression in human melanoma cells.How myeloma cells escape bisphosphonate-mediated killing: development of specific resistance with preserved sensitivity to conventional chemotherapeutics.Zoledronate sensitizes endothelial cells to tumor necrosis factor-induced programmed cell death: evidence for the suppression of sustained activation of focal adhesion kinase and protein kinase B/Akt.Zoledronic acid overcomes chemoresistance by sensitizing cancer stem cells to apoptosis.Are macrophages in tumors good targets for novel therapeutic approaches?
P2860
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P2860
The bisphosphonate zoledronic acid impairs Ras membrane [correction of impairs membrane] localisation and induces cytochrome c release in breast cancer cells.
description
2002 nî lūn-bûn
@nan
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
2002年论文
@zh
2002年论文
@zh-cn
name
The bisphosphonate zoledronic ...... elease in breast cancer cells.
@ast
The bisphosphonate zoledronic ...... elease in breast cancer cells.
@en
type
label
The bisphosphonate zoledronic ...... elease in breast cancer cells.
@ast
The bisphosphonate zoledronic ...... elease in breast cancer cells.
@en
prefLabel
The bisphosphonate zoledronic ...... elease in breast cancer cells.
@ast
The bisphosphonate zoledronic ...... elease in breast cancer cells.
@en
P2093
P2860
P356
P1476
The bisphosphonate zoledronic ...... elease in breast cancer cells.
@en
P2093
K W Colston
S G Senaratne
P2860
P2888
P304
P356
10.1038/SJ.BJC.6600297
P407
P577
2002-05-01T00:00:00Z