Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency. - Wikidata - wikimedia - TriplyDB

Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency.

Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency.

http://www.wikidata.org/entity/Q36648238

about

Macro histone variants are critical for the differentiation of human pluripotent cells Induced Pluripotent Stem Cells: Generation Strategy and Epigenetic Mystery behind Reprogramming Chromatin dynamics during cellular reprogramming Every amino acid matters: essential contributions of histone variants to mammalian development and disease Reprogramming of cell fate: epigenetic memory and the erasure of memories past A system for genome-wide histone variant dynamics in ES cells reveals dynamic MacroH2A2 replacement at promoters MacroH2A histone variants act as a barrier upon reprogramming towards pluripotency Heterochromatin Protein 1β (HP1β) has distinct functions and distinct nuclear distribution in pluripotent versus differentiated cells.Histone variants: emerging players in cancer biology.The histone variant H2A.Bbd is enriched at sites of DNA synthesis.Increased macroH2A1.1 expression correlates with poor survival of triple-negative breast cancer patients The histone variant MacroH2A1 regulates target gene expression in part by recruiting the transcriptional coregulator PELP1.Molecular control of induced pluripotency.Hierarchical molecular events driven by oocyte-specific factors lead to rapid and extensive reprogramming Mice without macroH2A histone variants.X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency Reprogramming the genome to totipotency in mouse embryos Epigenetic mechanisms of induced pluripotency.Maternal histone variants and their chaperones promote paternal genome activation and boost somatic cell reprogramming.MacroH2A1 associates with nuclear lamina and maintains chromatin architecture in mouse liver cells.X chromosome reactivation in reprogramming and in development Mechanisms underlying the formation of induced pluripotent stem cells.MacroH2A1 downregulation enhances the stem-like properties of bladder cancer cells by transactivation of Lin28B Epigenetics of reprogramming to induced pluripotency.The characterization of macroH2A beyond vertebrates supports an ancestral origin and conserved role for histone variants in chromatin Histone variants and cellular plasticity Chromatin changes in reprogramming of mammalian somatic cells.Multiple Roles of MYC in Integrating Regulatory Networks of Pluripotent Stem Cells.Gene Resistance to Transcriptional Reprogramming following Nuclear Transfer Is Directly Mediated by Multiple Chromatin-Repressive Pathways.The let-7/LIN-41 pathway regulates reprogramming to human induced pluripotent stem cells by controlling expression of prodifferentiation genes.Organizing the genome with H2A histone variants.The epigenetics of early development: inferences from stem cells.New proteomic insights on the role of NPR-A in regulating self-renewal of embryonic stem cells.Reprogramming barriers and enhancers: strategies to enhance the efficiency and kinetics of induced pluripotency Erase and Rewind: Epigenetic Conversion of Cell Fate.H3K9me3-Dependent Heterochromatin: Barrier to Cell Fate Changes.Epo-induced erythroid maturation is dependent on Plcγ1 signaling.The histone variant macroH2A confers functional robustness to the intestinal stem cell compartment.Histone MacroH2A1: A Chromatin Point of Intersection between Fasting, Senescence and Cellular Regeneration.Histone Variant MacroH2A1 Plays an Isoform-Specific Role in Suppressing Epithelial-Mesenchymal Transition.

P2860

Q24338629-C3A65324-65FA-424E-871B-0222CD6C46F4 Q26765848-C5975AE9-2B57-45BE-9057-3C5ECD70E8A4 Q27003401-6622178F-2D72-45FC-A77C-E2C3F8AFBDF7 Q27008522-BF063928-6D31-4E38-B2D1-ADF09E86AF47 Q27027748-9C4F5AF7-752E-4FF1-8666-66A3AB95BB17 Q27314729-65E65A20-B2F9-4C7E-B868-B3896974FF86 Q28571328-3CA102F2-4E87-4ADF-9A4D-430BFED86461 Q30666181-DB40B1E8-C19E-4B4A-B93A-8FE00C43B40C Q33630867-23754CA1-C4B8-4247-AA47-E568FC8E468B Q33698689-FA29666C-FD2F-4BD2-A904-E6B3FA1A85AC Q33727273-E9E3C834-ADCE-41F9-844C-368A2966B88B Q33743684-EDE265EC-2CFE-4E31-8C39-637C7B3E94CC Q33957979-1F80A8B4-3D83-474D-87A3-F2E1CD16B455 Q34142046-D9E5D19D-152D-4F8B-9F97-B407E4784E24 Q34592847-6F3CDC85-9654-4992-974E-F0E68BA37CAA Q34803951-BC0C829F-C782-40B2-9DBA-B3127A4A7BDF Q35034392-5E246AB2-CE8A-4278-A386-113F584BBF6A Q35066333-7F5F3903-6ACA-46B9-8F47-727967317F26 Q35837673-AF87E9B7-0155-4F83-BCAE-5CC9A0C51539 Q36316839-8747E258-75E3-4C45-B62F-1BFE1DFAE8BD Q36396148-7CDF8B45-5DFE-42D7-8D62-E6BDA266C2BE Q36469676-7E00F449-95DF-4CB7-BE2D-B37BCD7B7CFF Q36686246-8E4C60F1-3434-431E-92AF-DCECFCBBB13B Q36700557-CDE1C371-8CED-4C7D-B67C-FD49A03775C5 Q37082652-89ED87D5-85FC-4F5D-B0F4-F8210A57F8C7 Q37417597-EE7E116C-23E4-424D-A961-683689800A4D Q37593671-F69C843F-DAD7-4AC0-8C8F-8A976C647E23 Q37622098-33292931-D44A-4006-9530-85AF6C6806DC Q37691760-DDC14D88-C23E-416C-A198-62229334B814 Q37695727-0AE8003E-E13A-42F7-93B7-18017D9DE177 Q38072728-CFC8D5AA-47A8-4E54-BA09-1AD0DCBC7A57 Q38154838-449E7A2C-B525-4DF8-A88B-DFB1E34D37E9 Q38477100-D9E54A95-A6FC-4877-A9D6-4A0ED7921CFB Q38632891-7E2B1740-94F3-42C8-AAEE-F3A17BFC4093 Q38640670-E3B16ECE-5D3A-4812-9F61-D68C7A7382D7 Q38671298-D67B01AE-877E-4C92-AB61-12D9E3E49D61 Q40386692-BB3DCF7B-EC3C-4016-A725-698DC278D33D Q41983765-832B5772-2C1B-4011-A5F6-A85812BA760A Q47155763-FF7E16A5-2E9C-4225-96D3-B2ED67DD6DAE Q49218448-395E2CAD-4144-4AB0-8AB7-249BE594FA2D

P2860

Histone variant macroH2A marks embryonic differentiation in vivo and acts as an epigenetic barrier to induced pluripotency.

http://www.wikidata.org/entity/Q36648238

description

2012 nî lūn-bûn

@nan

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

2012年论文

@zh

2012年论文

@zh-cn

name

Histone variant macroH2A marks ...... rrier to induced pluripotency.

@ast

Histone variant macroH2A marks ...... rrier to induced pluripotency.

@en

type

label

Histone variant macroH2A marks ...... rrier to induced pluripotency.

@ast

Histone variant macroH2A marks ...... rrier to induced pluripotency.

@en

prefLabel

Histone variant macroH2A marks ...... rrier to induced pluripotency.

@ast

Histone variant macroH2A marks ...... rrier to induced pluripotency.

@en

P1433

Q36648238-7E98E8AA-EA59-430F-8A4D-86372E32619F

P1476

Q36648238-F26DD362-7676-4C5C-9CE8-F7C754EB682E

P2093

Q36648238-172772DB-593C-401E-9754-F3110F3DBC41

Q36648238-3513F079-4F4A-43D0-9D7A-EB39B1CD5704

Q36648238-D70CA785-A3A7-4222-AAF8-8DD772529E92

P2860

Q36648238-179E8955-AE49-407B-A102-414E76F23641

Q36648238-1A5E411B-43DC-4F91-8462-964259FF97DE

Q36648238-1BEFAD9D-1D89-418B-9FBE-E0A7B8B032FD

Q36648238-1C33749C-51C6-463D-918E-DF999BF8C0AE

Q36648238-2654DEC8-A704-4B75-A557-02902FF9EFEE

Q36648238-31401E1D-7912-44BF-8024-7C8AE0EFCE78

Q36648238-3BE8C9EC-0FC5-4AEF-AFBB-F57DB2CCE858

Q36648238-3FFDC348-B11A-40A7-9860-7FA673298F6A

Q36648238-43033124-7899-447A-9D62-D1538FBCC1BC

Q36648238-465198C3-B88E-4C36-B043-14500513A872

P304

Q36648238-AF4B2DC6-4770-4806-878B-B14DF26E3144

P31

Q36648238-F75954FD-266E-47F6-A102-5CF0E82F5949

P356

Q36648238-36B9B6F8-7352-4ECD-B5BB-AA65305977A6

P407

Q36648238-E605FF9A-E0D3-4018-99BC-ABC91C4035A3

P433

Q36648238-B214A5D6-2D8C-45E5-A309-017B61777518

P478

Q36648238-3C68A167-2159-45BE-A041-656959F9E148

P50

Q36648238-383E9E36-24D0-46EE-B0A9-F70E1E3AA40C

Q36648238-45066887-F171-429C-B85C-1525F1123680

Q36648238-6F2548AF-588A-4F11-9185-DDFF21B37040

Q36648238-EE269694-3CA2-4F86-A92A-A0E5C2DF5018

Q36648238-F41122BA-855C-4100-8CC6-D20F2BB510C7

P577

Q36648238-9DFF77AC-53A1-4EB6-A5E2-9976C9C09008

P5875

Q36648238-24D2E7E0-491C-436A-B0D9-249E418A7439

P698

Q36648238-73B55FEF-FB91-4D97-A788-1CF91C574677

P932

Q36648238-5BFB0434-F240-425B-A20E-FD0AA7CA6CA9

P356

P1433

Journal of Cell Science

P1476

Histone variant macroH2A marks ...... rrier to induced pluripotency.

@en

P2093

Aliaksandra Radzisheuskaya

http://www.w3.org/2001/XMLSchema#string

Astrid Gillich

http://www.w3.org/2001/XMLSchema#string

Maryna Panamarova

http://www.w3.org/2001/XMLSchema#string

P2860

The histone variant macroH2A1 marks repressed autosomal chromatin, but protects a subset of its target genes from silencing

The histone variant macroH2A is an epigenetic regulator of key developmental genes

Chromatin dynamics during epigenetic reprogramming in the mouse germ line

Synergism of Xist RNA, DNA methylation, and histone hypoacetylation in maintaining X chromosome inactivation

Dynamic in vivo imaging and cell tracking using a histone fluorescent protein fusion in mice

A macrodomain-containing histone rearranges chromatin upon sensing PARP1 activation

Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors

The histone variant macroH2A interferes with transcription factor binding and SWI/SNF nucleosome remodeling

Histone macroH2A1 is concentrated in the inactive X chromosome of female mammals

Promotion of reprogramming to ground state pluripotency by signal inhibition

P304

6094-6104

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1242/JCS.113019

http://www.w3.org/2001/XMLSchema#string

P407

P433

Pt 24

http://www.w3.org/2001/XMLSchema#string

P478

125

http://www.w3.org/2001/XMLSchema#string

P50

Magdalena Żernicka-Goetz

Richard P Halley-Stott

P577

2012-10-17T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

232281436

http://www.w3.org/2001/XMLSchema#string

P698

23077180

http://www.w3.org/2001/XMLSchema#string

P932

3585521

http://www.w3.org/2001/XMLSchema#string